Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Steven A. Baumeister"'
Autor:
Jürgen, Dinges, Kimba L, Ashworth, Irini, Akritopoulou-Zanze, Irini, Akritopolou-Zanze, Lee D, Arnold, Steven A, Baumeister, Peter F, Bousquet, George A, Cunha, Steven K, Davidsen, Stevan W, Djuric, Vijaya J, Gracias, Michael R, Michaelides, Paul, Rafferty, Thomas J, Sowin, Kent D, Stewart, Zhiren, Xia, Henry Q, Zhang
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:4266-4271
A series of 1,4-dihydroindeno[1,2-c]pyrazoles with a 3-thiophene substituent carrying a urea-type side chain were identified as potent multitargeted (VEGFR and PDGFR families) receptor tyrosine kinase inhibitors. A KDR homology model suggested that t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28684c9797329826d7cfb032e78b7827
https://doi.org/10.1016/j.bmcl.2006.05.066
https://doi.org/10.1016/j.bmcl.2006.05.066
Autor:
Jürgen Dinges, David A. Betebenner, Mark G. Bures, Philip J. Hajduk, Irini Zanze, Steven W. Elmore, Mary K. Joseph, Steven A. Baumeister, Stephen W. Fesik, Wang Shen, David G. Nettesheim, Shelley K. Landis, Andrew M. Petros, Sheela A. Thomas, David J. Augeri, Saul H. Rosenberg, Wang Xilu, Haichao Zhang
Publikováno v:
Journal of Medicinal Chemistry. 49:656-663
The antiapoptotic proteins Bcl-x(L) and Bcl-2 play key roles in the maintenance of normal cellular homeostasis. However, their overexpression can lead to oncogenic transformation and is responsible for drug resistance in certain types of cancer. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd5d8794ba4c78441c7a9ede6d41db9b
https://doi.org/10.1021/jm0507532
https://doi.org/10.1021/jm0507532
Autor:
Steven K. Davidsen, George A. Cunha, Henry Q. Zhang, Jürgen Dinges, Michael R. Michaelides, Lee D. Arnold, Vijaya Gracias, Zhiren Xia, Peter F. Bousquet, Paul Rafferty, Stevan W. Djuric, Steven A. Baumeister, Kent D. Stewart, Irini Akritopoulou-Zanze, Thomas J. Sowin, Kimba L. Ashworth
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:3516
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e1901913aa21b31cb30db679e0630cf
https://doi.org/10.1016/j.bmcl.2007.05.001
https://doi.org/10.1016/j.bmcl.2007.05.001