Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Steven A Tobery"'
Autor:
David K O'Brien, Wilson J Ribot, Donald J Chabot, Angelo Scorpio, Steven A Tobery, Tanya M Jelacic, Zhibin Wu, Arthur M Friedlander
Publikováno v:
PLoS Pathogens, Vol 18, Iss 9, p e1010851 (2022)
During infection, Bacillus anthracis bacilli encounter potent antimicrobial peptides (AMPs) such as defensins. We examined the role that B. anthracis capsule plays in protecting bacilli from defensins and other cationic AMPs by comparing their effect
Externí odkaz:
https://doaj.org/article/449889c9f71b4823a963f4ccffc61600
Autor:
Jennifer Chua, Joel A. Bozue, Christopher P. Klimko, Jennifer L. Shoe, Sara I. Ruiz, Christopher L. Jensen, Steven A. Tobery, Jared M. Crumpler, Donald J. Chabot, Avery V. Quirk, Melissa Hunter, David E. Harbourt, Arthur M. Friedlander, Christopher K. Cote
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 5, Pp 919-926 (2019)
For safety, designated Select Agents in tissues must be inactivated and viability tested before the tissue undergoes further processing and analysis. In response to the shipping of samples of “inactivated” Bacillus anthracis that inadvertently co
Externí odkaz:
https://doaj.org/article/ba56554c984b431ca3472bad3e9c2778
Autor:
Jennifer Chua, Ethan Nguyenkhoa, Sherry Mou, Steven A. Tobery, Arthur M. Friedlander, David DeShazer
Publikováno v:
Infect Immun
Burkholderia pseudomallei, the causative agent of melioidosis, is classified by the CDC as a tier 1 select agent, and work involving it must be performed in a biosafety level 3 (BSL-3) laboratory. Three BSL-2 surrogate strains derived from B. pseudom
Publikováno v:
ImmunoHorizons. 5:81-89
The capsule of Bacillus anthracis is composed of a d isomer poly-γ-glutamic acid polymer, which is especially nonstimulatory to dendritic cells, even more so than similar mixed d, l isomer polymers from nonpathogenic Bacillus species. Capsule is an
Autor:
Christopher P. Klimko, Chris W Schellhase, Nancy A. Twenhafel, Jeremy A. Miller, Christopher K. Cote, Donald J. Chabot, John R. Barr, Susham S. Ingavale, Mary E. Wright, Nicholas J. Vietri, Adrian R. Woolfitt, David P Fetterer, Anne E. Boyer, Brandon Somerville, Arthur M. Friedlander, Steven A. Tobery
Publikováno v:
J Infect Dis
Background Inhalational anthrax is rare and clinical experience limited. Expert guidelines recommend treatment with combination antibiotics including protein synthesis-inhibitors to decrease toxin production and increase survival, although evidence i
Autor:
Arthur M. Friedlander, Jared M. Crumpler, Melissa G. Hunter, Christopher P. Klimko, David E. Harbourt, Christopher K. Cote, Avery V. Quirk, Steven A. Tobery, Jennifer Chua, Jennifer L. Shoe, Donald J. Chabot, Christopher L. Jensen, Joel A. Bozue, Sara I. Ruiz
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 5, Pp 919-926 (2019)
For safety, designated Select Agents in tissues must be inactivated and viability tested before the tissue undergoes further processing and analysis. In response to the shipping of samples of “inactivated” Bacillus anthracis that inadvertently co
Publikováno v:
ImmunoHorizons. 5(2)
The capsule of
Autor:
Sylvia R. Trevino, Susan L. Welkos, Jennifer L. Dankmeyer, Christopher K. Cote, Patricia L. Worsham, Franco Rossi, Kei Amemiya, David M. Waag, Susham S. Ingavale, Xiankun Zeng, Taylor B. Chance, Steven J. Kern, David P Fetterer, Steven A. Tobery
Publikováno v:
Microbial pathogenesis. 155
Burkholderia mallei is a gram-negative obligate animal pathogen that causes glanders, a highly contagious and potentially fatal disease of solipeds including horses, mules, and donkeys. Humans are also susceptible, and exposure can result in a wide r
Autor:
J. Reinhardt, Joel A. Bozue, Steven A. Tobery, Susan L. Welkos, Alison D. O'Brien, Stephen C. Darnell, Patrick Sanz, L. Kaatz, A. D. Bassett, Farhang Alem, Christopher K. Cote
Publikováno v:
Journal of Medical Microbiology. 61:1380-1392
Current vaccine approaches to combat anthrax are effective; however, they target only a single protein [the protective antigen (PA) toxin component] that is produced after spore germination. PA production is subsequently increased during later vegeta
Autor:
Christopher K. Cote, Stephen F. Little, Wendy M. Webster, Steven A. Tobery, Joel A. Bozue, Wieslaw Swietnicki, Anthony Bassett
Publikováno v:
FEMS Microbiology Letters. 332:113-121
Yersinia pestis is the causative agent responsible for bubonic and pneumonic plague. The bacterium uses the pLcr plasmid-encoded type III secretion system to deliver virulence factors into host cells. Delivery requires ATP hydrolysis by the YscN ATPa