Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Steven A Buck"'
Autor:
Chengzhi Xie, Christina Drenberg, Holly Edwards, J Timothy Caldwell, Wei Chen, Hiroto Inaba, Xuelian Xu, Steven A Buck, Jeffrey W Taub, Sharyn D Baker, Yubin Ge
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79106 (2013)
Acute myeloid leukemia (AML) remains a challenging disease to treat and urgently requires new therapies to improve its treatment outcome. In this study, we investigated the molecular mechanisms underlying the cooperative antileukemic activities of pa
Externí odkaz:
https://doaj.org/article/87a3ed3a1db245feaeb470f0d47acbc5
Autor:
John Timothy Caldwell, Holly Edwards, Alan A Dombkowski, Steven A Buck, Larry H Matherly, Yubin Ge, Jeffrey W Taub
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68601 (2013)
It has been previously shown that acute myeloid leukemia (AML) patients with higher levels of GATA1 expression have poorer outcomes. Furthermore, pediatric Down syndrome (DS) patients with acute megakaryocytic leukemia (AMKL), whose blast cells almos
Externí odkaz:
https://doaj.org/article/b1d74a4ff5b541909f5627ced25f1d62
Autor:
Guan Wang, Holly Edwards, J Timothy Caldwell, Steven A Buck, William Y Qing, Jeffrey W Taub, Yubin Ge, Zhihong Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e76662 (2013)
High-risk neuroblastoma remains a therapeutic challenge with a long-term survival rate of less than 40%. Therefore, new agents are urgently needed to overcome chemotherapy resistance so as to improve the treatment outcome of this deadly disease. Hist
Externí odkaz:
https://doaj.org/article/a011d84d096a4cd4afdf4cac5b388ab8
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17138 (2011)
BACKGROUND: Pediatric acute myeloid leukemia (AML) remains a challenging disease to treat even with intensified cytarabine-based chemotherapy. Histone deacetylases (HDACs) have been reported to be promising therapeutic targets for treating AML. Howev
Externí odkaz:
https://doaj.org/article/06065f8e545a4d6aab266dd9e36a924a
Autor:
Ana C Xavier, Holly Edwards, Alan A Dombkowski, Tugce B Balci, Jason N Berman, Graham Dellaire, Chengzhi Xie, Steven A Buck, Larry H Matherly, Yubin Ge, Jeffrey W Taub
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27486 (2011)
Acute megakaryocytic leukemia (AMkL) in Down syndrome (DS) children is uniformly associated with somatic GATA1 mutations, which result in the synthesis of a shorter protein (GATA1s) with altered transactivation activity compared to the wild-type GATA
Externí odkaz:
https://doaj.org/article/cb472333e4c342d39a28ad9e72a23a6f
Autor:
Balazs Halmos, James Suh, Jane Liu, Manuel Doria, Jeffrey S. Ross, Sai-Hong Ignatius Ou, K. Cynthia Hsieh, Ranee Mehra, Vincent A. Miller, James A. Knost, Paul A. S. Fishkin, Philip J. Stephens, Garrett M. Frampton, Steven C. Buck, Alexa B. Schrock, Nir Peled, Nagla Abdel Karim, Siraj M. Ali, Jose A. Bufill, Rong Chen, Eduardo Braun, Shuyu D. Li
Publikováno v:
Journal of Thoracic Oncology. 12:932-942
Pulmonary sarcomatoid carcinoma (PSC) is a high-grade NSCLC characterized by poor prognosis and resistance to chemotherapy. Development of targeted therapeutic strategies for PSC has been hampered because of limited and inconsistent molecular charact
Publikováno v:
Journal of the Optical Society of America. A, Optics, image science, and vision. 35(4)
On bright surrounds, red-green-balanced yellow targets become greenish brown with decreased target luminance, and red-green-balanced brown targets become reddish yellow with increased target luminance. These effects imply luminance- and/or contrast-d
Autor:
Sérgio M. C. Nascimento, Steven L. Buck, Jan Kremers, John S. Werner, Rigmor C. Baraas, Delwin T. Lindsey, Michael A. Webster
Publikováno v:
Journal of the Optical Society of America. A, Optics, image science, and vision. 35(4)
This feature issue of the Journal of the Optical Society of America A (JOSA A) reflects the basic and applied research interests of members of the color vision community. Most of the articles stem from presentations at the 24th Biennial Symposium of
Autor:
Steven L. Buck
Publikováno v:
Journal of Vision. 19:35
Publikováno v:
Journal of the Optical Society of America. A, Optics, image science, and vision. 33(3)
Two experiments assessed mechanisms underlying brown induction by presenting a foveal target disk and concentric annular surround stimuli that varied in contrast relative to larger backgrounds. Stimuli were presented under monocular, binocular, and d