Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Steven, Lotz"'
Retraction Notice to: NPTX1 Regulates Neural Lineage Specification from Human Pluripotent Stem Cells
Autor:
Nathan C. Boles, Sarah E. Hirsch, Sheila Le, Barbara Corneo, Fadi Najm, Andrew P. Minotti, Qingjie Wang, Steven Lotz, Paul J. Tesar, Christopher A. Fasano
Publikováno v:
Cell Reports, Vol 43, Iss 1, Pp 113625- (2024)
Externí odkaz:
https://doaj.org/article/7d0dbdd8172d4352a1d70f452496b269
Autor:
Taylor Bertucci, Shravani Kakarla, Max A. Winkelman, Keith Lane, Katherine Stevens, Steven Lotz, Alexander Grath, Daylon James, Sally Temple, Guohao Dai
Publikováno v:
APL Bioengineering, Vol 7, Iss 3, Pp 036107-036107-17 (2023)
During embryonic development, endothelial cells (ECs) undergo vasculogenesis to form a primitive plexus and assemble into networks comprised of mural cell-stabilized vessels with molecularly distinct artery and vein signatures. This organized vascula
Externí odkaz:
https://doaj.org/article/298466156c8b467783a1161fb7d5c0cf
Autor:
Elizabeth S. Fisher, Matthew A. Amarante, Natasha Lowry, Steven Lotz, Farhad Farjood, Sally Temple, Caitlin E. Hill, Thomas R. Kiehl
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-20 (2022)
Abstract Background Immune cells play crucial roles after spinal cord injury (SCI). However, incomplete knowledge of immune contributions to injury and repair hinders development of SCI therapies. We leveraged single-cell observations to describe key
Externí odkaz:
https://doaj.org/article/39f8184c71e8442786c7940482032cd2
Autor:
Mythily Ganapathi, Nathan C. Boles, Carol Charniga, Steven Lotz, Melissa Campbell, Sally Temple, Randall H. Morse
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Abstract The ability of isolated neural stem cells (NSCs) to proliferate as neurospheres is indicative of their competence as stem cells, and depends critically on the polycomb group (PcG) member Bmi1: knockdown of Bmi1 results in defective prolifera
Externí odkaz:
https://doaj.org/article/bb6451d396854ca396639407b1055802
Autor:
Stella M K, Glasauer, Susan K, Goderie, Jennifer N, Rauch, Elmer, Guzman, Morgane, Audouard, Taylor, Bertucci, Shona, Joy, Emma, Rommelfanger, Gabriel, Luna, Erica, Keane-Rivera, Steven, Lotz, Susan, Borden, Aaron M, Armando, Oswald, Quehenberger, Sally, Temple, Kenneth S, Kosik
Publikováno v:
Stem Cell Reports. 17:2127-2140
Mutations in the MAPT gene that encodes tau lead to frontotemporal dementia (FTD) with pathology evident in both cerebral neurons and glia. Human cerebral organoids (hCOs) from individuals harboring pathogenic tau mutations can reveal the earliest do
Autor:
James A. Gregory, Emily Hoelzli, Rawan Abdelaal, Catherine Braine, Miguel Cuevas, Madeline Halpern, Natalie Barretto, Nadine Schrode, Güney Akbalik, Kristy Kang, Esther Cheng, Kathryn Bowles, Steven Lotz, Susan Goderie, Celeste M. Karch, Sally Temple, Alison Goate, Kristen J. Brennand, Hemali Phatnani
Publikováno v:
Cells, Vol 9, Iss 6, p 1406 (2020)
Genetic and genomic studies of brain disease increasingly demonstrate disease-associated interactions between the cell types of the brain. Increasingly complex and more physiologically relevant human-induced pluripotent stem cell (hiPSC)-based models
Externí odkaz:
https://doaj.org/article/051c6b7b3fc94f27b8244d1722c52ff2
Autor:
Nathan C. Boles, Sarah E. Hirsch, Sheila Le, Barbara Corneo, Fadi Najm, Andrew P. Minotti, Qingjie Wang, Steven Lotz, Paul J. Tesar, Christopher A. Fasano
Publikováno v:
Cell Reports, Vol 6, Iss 4, Pp 724-736 (2014)
Neural induction is the first fundamental step in nervous system formation. During development, a tightly regulated niche modulates transient extracellular signals to influence neural lineage commitment. To date, however, the cascade of molecular eve
Externí odkaz:
https://doaj.org/article/95bbf450f8af451583aca65d7d5f7cb4
Autor:
Keith P. Lane, Kevin H. Strang, John F. Crary, Jesse D. Lai, Jacob C. Garza, Jacob A. Marsh, Sidhartha Mahali, Susan K. Goderie, Rebecca Chowdhury, Charles D. Chen, Sally Temple, Kathryn Bowles, Derian A. Pugh, Alison Goate, Nathan C. Boles, Stephen J. Haggarty, Justin K. Ichida, Taylor B. Bertucci, Celeste M. Karch, Kristen Whitney, Yiyuan Liu, Joshua E. Berlind, Silva Mc, Steven Lotz, Onanuga K
SUMMARYFrontotemporal dementia (FTD) due to MAPT mutation causes pathological accumulation of tau and glutamatergic cortical neuronal death by unknown mechanisms. We used human induced pluripotent stem cell (iPSC)-derived cerebral organoids expressin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e793e0899c0c7502147e6423449d206c
https://doi.org/10.1101/2021.02.03.429623
https://doi.org/10.1101/2021.02.03.429623
Autor:
Sidhartha Mahali, Derian A. Pugh, Kristen Whitney, Stephen J. Haggarty, Justin K. Ichida, Yiyuan Liu, Kathryn R. Bowles, Ronald E. Gordon, Alison Goate, Joshua E. Berlind, Steven Lotz, Susan K. Goderie, Nathan C. Boles, Kevin H. Strang, John F. Crary, Celeste M. Karch, Taylor B. Bertucci, M. Catarina Silva, Keith P. Lane, Jesse D. Lai, Jacob A. Marsh, Rebecca Chowdhury, Sally Temple, Jacob C. Garza, Cynthia Chen
Publikováno v:
Cell. 184(17)
Summary Frontotemporal dementia (FTD) because of MAPT mutation causes pathological accumulation of tau and glutamatergic cortical neuronal death by unknown mechanisms. We used human induced pluripotent stem cell (iPSC)-derived cerebral organoids expr
Autor:
Steven Lotz, Susan Goderie, Nicolas Tokas, Sarah E Hirsch, Faizzan Ahmad, Barbara Corneo, Sheila Le, Akhilesh Banerjee, Ravi S Kane, Jeffrey H Stern, Sally Temple, Christopher A Fasano
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56289 (2013)
An essential aspect of stem cell culture is the successful maintenance of the undifferentiated state. Many types of stem cells are FGF2 dependent, and pluripotent stem cells are maintained by replacing FGF2-containing media daily, while tissue-specif
Externí odkaz:
https://doaj.org/article/0a405e644030427d8c9ac37aa9fb1d98