Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Steven, Gerondakis"'
Autor:
Barbara C. Mindt, Sai Sakktee Krisna, Claudia U. Duerr, Mathieu Mancini, Lara Richer, Silvia M. Vidal, Steven Gerondakis, David Langlais, Jörg H. Fritz
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Group 2 innate lymphoid cells (ILC2s) play a key role in the initiation and orchestration of early type 2 immune responses. Upon tissue damage, ILC2s are activated by alarmins such as IL-33 and rapidly secrete large amounts of type 2 signature cytoki
Externí odkaz:
https://doaj.org/article/71c35d55ad3341a481a892ff468e1673
Autor:
Devy Deliyanti, Dean M. Talia, Tong Zhu, Mhairi J. Maxwell, Alex Agrotis, Jack R. Jerome, Emily M. Hargreaves, Steven Gerondakis, Margaret L. Hibbs, Fabienne Mackay, Jennifer L. Wilkinson-Berka
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The local immune responses in the eye are attenuated to preserve sight. Surprisingly, Deliyanti et al. show that regulatory T cells (Tregs) take an active role in protecting the eye from neovascularization in oxygen-induced retinopathy, and that inte
Externí odkaz:
https://doaj.org/article/50f3675a81e5466f9c5075205f5d2ecb
Autor:
Lloyd A Pereira, Honor J Hugo, Jordane Malaterre, Xu Huiling, Secondo Sonza, Alina Cures, Damian F J Purcell, Paul A Ramsland, Steven Gerondakis, Thomas J Gonda, Robert G Ramsay
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122919 (2015)
MYB transcriptional elongation is regulated by an attenuator sequence within intron 1 that has been proposed to encode a RNA stem loop (SLR) followed by a polyU tract. We report that NFκBp50 can bind the SLR polyU RNA and promote MYB transcriptional
Externí odkaz:
https://doaj.org/article/58f830945ef84465895b95b19a73adef
Autor:
Devy, Deliyanti, Dean M, Talia, Tong, Zhu, Mhairi J, Maxwell, Alex, Agrotis, Jack R, Jerome, Emily M, Hargreaves, Steven, Gerondakis, Margaret L, Hibbs, Fabienne, Mackay, Jennifer L, Wilkinson-Berka
Publikováno v:
Nature communications. 8(1)
Neovascular retinopathies are major causes of vision loss; yet treatments to prevent the condition are inadequate. The role of regulatory T cells in neovascular retinopathy is unknown. Here we show that in retinopathy regulatory T cells are transient