Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Steven, Cardinale"'
Autor:
Cecilia Gutierrez-Perez, Charles Puerner, Jane T. Jones, Sandeep Vellanki, Elisa M. Vesely, Mark A. Xatse, Andre F. C. Viera, Carissa P. Olsen, Keren O. Attiku, Steven Cardinale, Steven M. Kwasny, Narendran G-Dayanandan, Timothy J. Opperman, Robert A. Cramer
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Contemporary antifungal therapies utilized to treat filamentous fungal infections are inhibited by intrinsic and emerging drug resistance. Consequently, there is an urgent need to develop novel antifungal compounds that are effective against
Externí odkaz:
https://doaj.org/article/6c6f0dfdb29846f4968aadcda7933aa2
Autor:
Jamal Chauhan, Steven Cardinale, Lei Fang, Jing Huang, Steven M Kwasny, M Ross Pennington, Kelly Basi, Robert diTargiani, Benedict R Capacio, Alexander D MacKerell, Timothy J Opperman, Steven Fletcher, Erik P H de Leeuw
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164515 (2016)
Recently we described a novel di-benzene-pyrylium-indolene (BAS00127538) inhibitor of Lipid II. BAS00127538 (1-Methyl-2,4-diphenyl-6-((1E,3E)-3-(1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)pyryl-1-ium) tetrafluoroborate is the first small molecul
Externí odkaz:
https://doaj.org/article/3b20d0e6c31f4ac6bf0d0a03d1cf8c71
Autor:
Jay, Chauhan, Wenbo, Yu, Steven, Cardinale, Timothy J, Opperman, Alexander D, MacKerell, Steven, Fletcher, Erik Ph, de Leeuw
Publikováno v:
Drug Design, Development and Therapy
Background The bacterial cell envelope is comprised of the cell membrane and the cell wall. The bacterial cell wall provides rigidity to the cell and protects the organism from potential harmful substances also. Cell wall biosynthesis is an important
Autor:
Chamanie Amaratunga, Manickam Sugumaran, Timothy Scott, Steven Cardinale, Kaliappan Nellaiappan
Publikováno v:
Archives of Biochemistry and Biophysics. 378:393-403
Tyrosinase initiates melanogenesis in a variety of organisms. The nature of melanin formed is modified subsequently by dopachrome isomerase and other melanogenic proteins. Earlier, we reported the partial purification of dopachrome isomerase (decarbo
Publikováno v:
Journal of Biological Chemistry. 271:11035-11038
Hemolymph of fifth instar Manduca sexta larvae collected under non-sterile conditions exhibited the presence of a novel high molecular weight protein complex, which was absent from the hemolymph collected aseptically. The high molecular weight comple