Membrane-type 1 Matrix Metalloproteinase Modulates Tissue Homeostasis by a Non-proteolytic Mechanism

Autor: Mukundan Attur, Cuijie Lu, Xiaodong Zhang, Tianzhen Han, Cassidy Alexandre, Cristina Valacca, Shuai Zheng, Sarina Meikle, Branka Brukner Dabovic, Evelyne Tassone, Qing Yang, Victoria Kolupaeva, Shoshana Yakar, Steven Abramson, Paolo Mignatti

Publikováno v: iScience, Vol 23, Iss 12, Pp 101789- (2020)

Summary: Membrane-type 1 matrix metalloproteinase (MT1-MMP, MMP-14), a transmembrane proteinase with a short cytoplasmic tail, is a major effector of extracellular matrix remodeling. Genetic silencing of MT1-MMP in mouse (Mmp14−/−) and man causes

Externí odkaz: https://doaj.org/article/c75bb8befb1a45eeb5542b86036af6fd

A Preliminary Evaluation of Students' Learning and Performance Outcomes in an Accelerated 3-Year MD Pathway Program

Autor: Joan Cangiarella, Kinga Eliasz, Adina Kalet, Elisabeth Cohen, Steven Abramson, Colleen Gillespie

Publikováno v: J Grad Med Educ

Background Little outcome data exist on 3-year MD (3YMD) programs to guide residency program directors (PDs) in deciding whether to select these graduates for their programs. Objective To compare performance outcomes of 3YMD and 4-year MD (4YMD) stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70b4b4920519edbceeda5329074fc2c7
https://europepmc.org/articles/PMC8848877/

Contributors

Autor: Steven Abramson, KaiNan An, Felipe Andrade, Stacy P. Ardoin, Anne Barton, Robert P. Baughman, Dorcas E. Beaton, Helen M. Beere, Javier Beltran, David Bending, Robert M. Bennett, Bonnie L. Bermas, George Bertsias, Nina Bhardwaj, Johannes W.J. Bijlsma, Linda K. Bockenstedt, Maarten Boers, Eric Boilard, Francesco Boin, Dimitrios T. Boumpas, David L. Boyle, Sean Bradley, Matthew Brown, Maya Buch, Christopher D. Buckley, Ralph C. Budd, Nathalie Burg, Christopher M. Burns, Amy C. Cannella, John D. Carter, Eliza F. Chakravarty, Soumya D. Chakravarty, Christopher Chang, Joseph S. Cheng, Christopher P. Chiodo, Sharon Chung, Leslie G. Cleland, Stanley Cohen, Robert A. Colbert, Paul P. Cook, Joseph E. Craft, Leslie J. Crofford, Bruce N. Cronstein, Mary K. Crow, Cynthia S. Crowson, Kirsty L. Culley, Gaye Cunnane, Maria Dall'Era, Erika Darrah, John M. Davis, Cosimo De Bari, Francesco Dell'Accio, Betty Diamond, Paul E. Di Cesare, Rajiv Dixit, Joost P.H. Drenth, Michael L. Dustin, Hani S. El-Gabalawy, Musaab Elmamoun, Alan R. Erickson, Doruk Erkan, Stephen Eyre, Antonis Fanouriakis, David T. Felson, Max Field, Andrew Filer, Gary S. Firestein, Felicity G. Fishman, Oliver FitzGerald, John P. Flaherty, César E. Fors, Karen A. Fortner, Sherine E. Gabriel, Philippe Gasque, M. Eric Gershwin, Heather S. Gladue, Mary B. Goldring, Steven R. Goldring, Yvonne M. Golightly, Stuart Goodman, Siamon Gordon, Walter Grassi, Douglas R. Green, Adam Greenspan, Peter Gregersen, Christine Grimaldi, Luiza Guilherme, Rula A. Hajj-Ali, Dominik R. Haudenschild, David B. Hellmann, Rikard Holmdahl, Joyce J. Hsu, James I. Huddleston, Alan P. Hudson, Thomas W.J. Huizinga, Gene G. Hunder, Maura D. Iversen, Johannes W.G. Jacobs, Ho Jen, Joanne M. Jordan, Joseph L. Jorizzo, Jorge Kalil, Kenton Kaufman, William S. Kaufman, Arthur Kavanaugh, Robert T. Keenan, Tony Kenna, Darcy A. Kerr, Alisa E. Koch, Dwight H. Kono, Peter Korsten, Deborah Krakow, Svetlana Krasnokutsky, Floris P.J.G. Lafeber, Robert G.W. Lambert, Nancy E. Lane, Carol A. Langford, Daniel M. Laskin, Gerlinde Layh-Schmitt, Lela A. Lee, Tzielan C. Lee, Michael D. Lockshin, Carlos J. Lozada, Ingrid E. Lundberg, Raashid Luqmani, Frank P. Luyten, Reuven Mader, Walter Maksymowych, Joseph A. Markenson, Scott David Martin, Eric L. Matteson, Laura McGregor, Iain B. McInnes, Elizabeth K. McNamara, Ted R. Mikuls, Mark S. Miller, Pedro Azevedo Ming, Kevin G. Moder, Paul A. Monach, Vaishali R. Moulton, Kanneboyina Nagaraju, Amanda E. Nelson, Peter A. Nigrovic, Kiran Nistala, James R. O'Dell, Yasunori Okada, Mikkel Østergaard, Miguel Otero, Bradley M. Palmer, Richard S. Panush, Stanford L. Peng, Shiv Pillai, Michael H. Pillinger, Annette Plüddemann, Gregory R. Polston, Steven A. Porcelli, Mark D. Price, Ann M. Reed, John D. Reveille, Angela B. Robinson, Philip Robinson, William H. Robinson, Goris Roosendaal, Antony Rosen, James T. Rosenbaum, Andrew E. Rosenberg, Eric M. Ruderman, Kenneth G. Saag, Jane E. Salmon, Lisa R. Sammaritano, Jonathan Samuels, Christy I. Sandborg, Amr H. Sawalha, Amit Saxena, Georg Schett, Roger E.G. Schutgens, David C. Seldin, Binita Shah, Keith A. Sikora, Anna Simon, Dawd S. Siraj, Linda S. Sorkin, E. William St. Clair, Lisa K. Stamp, John H. Stone, Abel Suarez-Fueyo, Camilla I. Svensson, Nadera J. Sweiss, Carrie R. Swigart, Zoltán Szekanecz, Stephen Tait, Antoine Tanne, Peter C. Taylor, Robert Terkeltaub, Argyrios N. Theofilopoulos, Thomas S. Thornhill, Kathryn S. Torok, Michael J. Toth, Elaine C. Tozman, Leendert A. Trouw, George C. Tsokos, Peter Tugwell, Zuhre Tutuncu, Shivam Upadhyaya, Annette H.M. Van, Sjef van der Linden, Jos W.M. Van, Jacob M. Van, Heather Van Meter, Ronald F. van Vollenhoven, Lize F.D. van Vulpen, John Varga, Samera Vaseer, Raul Vasquez-Castellanos, Douglas J. Veale, Richard J. Wakefield, Mark S. Wallace, Ruoning Wang, Tingting Wang, David M. Warshaw, Lucy R. Wedderburn, Victoria P. Werth, Fredrick M. Wigley, David Wofsy, Frank A. Wollheim, Elisabeth Wondimu, Cyrus Wong, Robert L. Wortmann, Edward Yelin, Ahmed Zayat, Yong-Rui Zou, Robert B. Zurier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::349a5ec844200bfaa349c3866d042477
https://doi.org/10.1016/b978-0-323-31696-5.00129-7

T1rho MRI of menisci in patients with osteoarthritis at 3 Tesla: a preliminary study

Autor: Ligong, Wang, Gregory, Chang, Jenny, Bencardino, James S, Babb, Svetlana, Krasnokutsky, Steven, Abramson, Ravinder R, Regatte

Publikováno v: Journal of magnetic resonance imaging : JMRI. 40(3)

To compare and assess subregional, compartmental, and whole T1rho values of menisci in patients with doubtful-minimal (Kellgren-Lawrence [KL] grade 1-2) as compared to moderate-severe (KL3-4) osteoarthritis (OA) and healthy controls at 3 Tesla (T).Fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1de60cf63da94c45d02b508361d6e994
https://pubmed.ncbi.nlm.nih.gov/24395433

Biomarkers in osteoarthritis

Autor: Steven, Abramson, Svetlana, Krasnokutsky

Publikováno v: Bulletin of the NYU hospital for joint diseases. 64(1-2)

Osteoarthritis (OA) can be a progressive disabling disease, which results from the pathological imbalance of degradative and reparative processes, with concomitant inflammatory changes. The synovium, bone, and cartilage are each well established site

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4455728e86d2e8b6ce1c28afdb2ecd44
https://pubmed.ncbi.nlm.nih.gov/17121495