Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Steve Zaldua"'
Autor:
Rima Rebiai, Emily Rue, Steve Zaldua, Duc Nguyen, Giuseppe Scesa, Martin Jastrzebski, Robert Foster, Bin Wang, Xuntian Jiang, Leon Tai, Scott T. Brady, Richard van Breemen, Maria I. Givogri, Mark S. Sands, Ernesto R. Bongarzone
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Krabbe Disease (KD) is a lysosomal storage disorder characterized by the genetic deficiency of the lysosomal enzyme β-galactosyl-ceramidase (GALC). Deficit or a reduction in the activity of the GALC enzyme has been correlated with the progressive ac
Externí odkaz:
https://doaj.org/article/ebdde43cc35d4f9e87b3d663556551e0
Autor:
Sarah B. Scheinman, Steve Zaldua, Adedoyin Dada, Kateryna Krochmaliuk, Katherine Dye, Felecia M. Marottoli, Gregory R. J. Thatcher, Leon M. Tai
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Evidence suggests that angiotensin receptor blockers (ARBs) could be beneficial for Alzheimer’s disease (AD) patients independent of any effects on hypertension. However, studies in rodent models directly testing the activity of ARB treatment on be
Externí odkaz:
https://doaj.org/article/fb542f03343d4d58bac9899b5cd12600
Autor:
Steve Zaldua, Frederick C. Damen, Rohan Pisharody, Riya Thomas, Kelly D. Fan, Giri K. Ekkurthi, Sarah B. Scheinman, Sami Alahmadi, Felecia M. Marottoli, Simon Alford, Kejia Cai, Leon M. Tai
Publikováno v:
Heliyon, Vol 6, Iss 5, Pp e03919- (2020)
APOE4 is a major genetic risk factor for Alzheimer's disease and high amyloid-β (Aβ) levels in the brain are a pathological hallmark of the disease. However, the contribution of specific APOE-modulated Aβ-dependent and Aβ-independent functions to
Externí odkaz:
https://doaj.org/article/06357e93928d40f2a899d980172f381e
Autor:
Steve Zaldua, Adedoyin Dada, Gregory R. J. Thatcher, Kateryna Krochmaliuk, Katherine Dye, Felecia M. Marottoli, Leon M. Tai, Sarah B. Scheinman
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Evidence suggests that angiotensin receptor blockers (ARBs) could be beneficial for Alzheimer’s disease (AD) patients independent of any effects on hypertension. However, studies in rodent models directly testing the activity of ARB treatment on be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::262f8ca5aa297adb7aca884a9c952739
https://doi.org/10.3389/fnins.2021.628403
https://doi.org/10.3389/fnins.2021.628403
Autor:
Riya Thomas, Kejia Cai, Felecia M. Marottoli, Sarah B. Scheinman, Rohan Pisharody, Leon M. Tai, Kelly D. Fan, Frederick C. Damen, Simon Alford, Sami Alahmadi, Giri K. Ekkurthi, Steve Zaldua
Publikováno v:
Heliyon
Heliyon, Vol 6, Iss 5, Pp e03919-(2020)
Heliyon, Vol 6, Iss 5, Pp e03919-(2020)
APOE4 is a major genetic risk factor for Alzheimer's disease and high amyloid-β (Aβ) levels in the brain are a pathological hallmark of the disease. However, the contribution of specific APOE-modulated Aβ-dependent and Aβ-independent functions to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0034e1c5b16ac1a8115b581245f2fbe1
http://europepmc.org/articles/PMC7251379
http://europepmc.org/articles/PMC7251379
Publikováno v:
Molecular nutritionfood research. 64(12)
Scope Currently available omega-3 fatty acid supplements do not enrich the docosahexaenoic acid (DHA) of the adult brain because they are absorbed as triacylglycerol, whereas the transporter at the blood brain barrier requires lysophosphatidylcholine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30a58a4738cadddf6b4fed9ea04e49a
https://pubmed.ncbi.nlm.nih.gov/32304625
https://pubmed.ncbi.nlm.nih.gov/32304625
Autor:
Mercedes Priego, Scott T. Brady, Kuei Y. Tseng, Rohan Pisharody, Kelly D. Fan, Leon M. Tai, Felecia M. Marottoli, Gerardo Morfini, Eden Flores-Barrera, Steve Zaldua, Giri K. Ekkurthi
Publikováno v:
Mol Neurobiol
Recent evidence indicates that disruption of epidermal growth factor (EGF) signaling by mutant huntingtin (polyQ-htt) may contribute to the onset of behavioral deficits observed in Huntington’s disease (HD) through a variety of mechanisms, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef4581b35de1e0cfd80aa65af8e7392d
https://pubmed.ncbi.nlm.nih.gov/31104296
https://pubmed.ncbi.nlm.nih.gov/31104296