Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Steve Wiltshire"'
Polymorphisms associated with normal memory variation also affect memory impairment in schizophrenia
Autor:
Steve Wiltshire, Assen Jablensky, Johanna C. Badcock, Luba Kalaydjieva, Kirsten Peters, Kim W. Carter, David Chandler, Milan Dragovic, Bharti Morar
Publikováno v:
Genes, Brain and Behavior. 10:410-417
Neurocognitive dysfunction is a core feature of schizophrenia with particularly prominent deficits in verbal episodic memory. The molecular basis of this memory impairment is poorly understood and its relatedness to normal variation in memory perform
Autor:
Eleftheria Zeggini, C J Groves, Stephen O'Rahilly, Desmond G. Johnston, Graham A. Hitman, Mark I. McCarthy, Mark Walker, Timothy M. Frayling, Katharine R. Owen, J C Levy, Steve Wiltshire, C.F. Liew, Andrew T. Hattersley
Publikováno v:
Diabetologia. 47:2168-2175
AIMS/HYPOTHESIS: Stearoyl-CoA desaturase (SCD) is emerging as a key regulator of lipid and carbohydrate metabolism. Scd-null mice display a beneficial metabolic phenotype characterised by resistance to obesity, diabetes and hyperlipidaemia. The human
Autor:
James Xia, Heshu Huang, Linhua Fang, R. Murli Krishna, Lei Sun, Chang-Gong Liu, Jaymie Robin Sawyer, Girish Nallur, Barry Schweitzer, Chenghua Luo, Robert Marrero, Weiping Shao, Pamela E. Bechtel, Stephen F. Kingsmore, Steve Wiltshire, Melissa Ray
Publikováno v:
Biomedical Microdevices. 5:115-123
Microarrays are becoming the platform of choice for the analysis of complex genomes, transcriptomes and proteomes. For a number of applications, however, sample or analyte abundance constraints limit the usefulness of microarrays. Rolling circle ampl
Paraoxonase 2 (PON2) polymorphisms and development of renal dysfunction in type 2 diabetes: UKPDS 76
Autor:
J. Richmond, David Albert Fryburg, Mark I. McCarthy, Carole A. Cull, D. Meyer, Roberto A. Calle, P. Banerjee, Steve Wiltshire, James P. Mancuso, Steven G. Terra, K.I. Thorne, Rury R. Holman, Eleftheria Zeggini, Patrice M. Milos
Publikováno v:
Diabetologia. 49(12)
AIMS/HYPOTHESIS: Identification of variants predicting development of renal dysfunction would offer substantial clinical benefits. There is evidence that coding non-synonymous variants in the gene encoding paraoxonase 2 (PON2) are associated with nep
Autor:
Guannan Kuang, Csaba Pazmany, Mark Toews, Daniel J. Sexton, Kris Kopacz, Judith Jacques, Janja Cosic, Dina Wassaf, Robert Charles Ladner, Andrew E. Nixon, Jeremy Lambert, Steve Wiltshire, Shannon Hogan, Qi-Long Wu, Que Nguyen
Publikováno v:
Analytical biochemistry. 351(2)
A method was developed to rapidly identify high-affinity human antibodies from phage display library selection outputs. It combines high-throughput Fab fragment expression and purification with surface plasmon resonance (SPR) microarrays to determine
Publikováno v:
Genomics. 72(1)
Linkage and association of polymorphic markers in the chromosome 5q31-q33 cytokine cluster to atopy and asthma associated phenotypes have been reported by a number of groups. To investigate this region, 29 polymorphic markers were used to genotype a
Publikováno v:
Diabetic medicine : a journal of the British Diabetic Association. 18(3)
SUMMARY Aims The beta-cell ATP-sensitive potassium channel consists of two subunits, SUR1 and Kir6.2. Population association studies have shown that three variants in SUR1 and one in Kir6.2 are associated with Type 2 diabetes. These polymorphisms do
Publikováno v:
Journal of Allergy and Clinical Immunology. 109:S231-S231
Publikováno v:
Clinical Chemistry. 47:1929-1929
Allergen-specific IgE antibody in patient serum is used to predict an allergic response in individuals with concordant clinical history. For more than 30 years, in vitro assays for allergen-specific IgE have been used along with or in place of skin-p
Autor:
Kari Kukanskis, Shawn O’Malley, Jeremy Lambert, Steve Wiltshire, David Edgar, Stephen F. Kingsmore, Barry Schweitzer
Publikováno v:
Europe PubMed Central
First described in 1967, the radio allergo sorbent test (RAST) has been the standard technique for measuring allergen-specific IgE antibodies in serum (1). An updated version of the RAST test, termed CAP (Pharmacia), has been introduced (2). In clini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03ce26c4807f09719d903416da8367f
http://europepmc.org/abstract/med/11106333
http://europepmc.org/abstract/med/11106333