Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Steve W. Turner"'
Publikováno v:
Breathe, Vol 15, Iss 4, Pp 306-316 (2019)
Exhaled nitric oxide fraction (FENO) values can be easily measured using portable analysers and are a surrogate marker of airway eosinophilia. FENO may be useful in diagnosing and monitoring conditions characterised by airway eosinophilia, i.e. asthm
Externí odkaz:
https://doaj.org/article/7604713c5f3e4708b809e54603b4807d
Autor:
Richard Thomas, Holly Tibble, Laura J Bonnett, Luke Daines, David Price, Steff C Lewis, Hilary Pinnock, Andy Boyd, Aziz Sheikh, Steve W Turner
Publikováno v:
Wellcome Open Research, Vol 8 (2023)
Introduction: Accurately diagnosing asthma can be challenging. We aimed to derive and validate a prediction model to support primary care clinicians assess the probability of an asthma diagnosis in children and young people. Methods: The derivation d
Externí odkaz:
https://doaj.org/article/09f7e997b1eb43cf89175093c147cc30
Autor:
Raquel Granell, John A Curtin, Sadia Haider, Negusse Tadesse Kitaba, Sara A Mathie, Lisa G Gregory, Laura L Yates, Mauro Tutino, Jenny Hankinson, Mauro Perretti, Judith M Vonk, Hasan S Arshad, Paul Cullinan, Sara Fontanella, Graham C Roberts, Gerard H Koppelman, Angela Simpson, Steve W Turner, Clare S Murray, Clare M Lloyd, John W Holloway, Adnan Custovic, on behalf of UNICORN and Breathing Together investigators
Publikováno v:
eLife, Vol 12 (2023)
Background: Many genes associated with asthma explain only a fraction of its heritability. Most genome-wide association studies (GWASs) used a broad definition of ‘doctor-diagnosed asthma’, thereby diluting genetic signals by not considering asth
Externí odkaz:
https://doaj.org/article/ef3714c583a24ddeb37692801c1faf88
Autor:
Luke Daines, Laura J Bonnett, Holly Tibble, Andy Boyd, Richard Thomas, David Price, Steve W Turner, Steff C Lewis, Aziz Sheikh, Hilary Pinnock
Publikováno v:
Wellcome Open Research. 8:195
Introduction: Accurately diagnosing asthma can be challenging. We aimed to derive and validate a prediction model to support primary care clinicians assess the probability of an asthma diagnosis in children and young people. Methods: The derivation d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f16e3a8aed7072d6030f99d58b1974
https://doi.org/10.12688/wellcomeopenres.19078.1
https://doi.org/10.12688/wellcomeopenres.19078.1
Autor:
David Miller, Steve W Turner, Daniella Spiteri-Cornish, Neil McInnes, Alison Scaife, Peter J Danielian, Graham Devereux, Garry M Walsh
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78321 (2013)
INTRODUCTION:Little is known about how neonatal airway epithelial cell phenotype impacts on respiratory disease in later life. This study aimed to establish a methodology to culture and characterise neonatal nasal epithelial cells sampled from health
Externí odkaz:
https://doaj.org/article/c0c227b88f734d609b98d1cdab830e37
Autor:
Omar Jabado, Richard J. Roberts, Gintaras Deikus, Michael C. Chao, Steve W. Turner, Anjali Mandlik, Bojan Losic, Diana Munera, Brigid M. Davis, Milind Mahajan, Vipin Kumar, Khai Luong, Gang Fang, Zhixing Feng, Jonas Korlach, Tyson A. Clark, Andrew Chess, Onureena Banerjee, David I. Friedman, Iain A. Murray, Matthew K. Waldor, Alona Keren-Paz, Eric E. Schadt
Publikováno v:
Nature Biotechnology. 30:1232-1239
Single-molecule real-time (SMRT) DNA sequencing allows the systematic detection of chemical modifications such as methylation but has not previously been applied on a genome-wide scale. We used this approach to detect 49,311 putative 6-methyladenine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e588c4fc04eb91000741928e92faa066
https://doi.org/10.1038/nbt.2432
https://doi.org/10.1038/nbt.2432
Autor:
Steve W. Turner
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 7:541-544
Asthma is a chronic respiratory condition affecting many adults and children. An association between asthma and raised gaseous nitric oxide in the exhaled breath was first reported in 1993. In the absence of an objective test for diagnosing and monit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa9959df8f6c516f3d8320dbb32d0ef9
https://doi.org/10.2174/138955707780619635
https://doi.org/10.2174/138955707780619635
Autor:
Steve, Cunningham, Aryelly, Rodriguez, Tim, Adams, Kathleen A, Boyd, Isabella, Butcher, Beth, Enderby, Morag, MacLean, Jonathan, McCormick, James Y, Paton, Fiona, Wee, Huw, Thomas, Kay, Riding, Steve W, Turner, Chris, Williams, Emma, McIntosh, Steff C, Lewis, Allan, Walker
Publikováno v:
Cunningham, S, Rodriguez, A, Adams, T, Boyd, K A, Butcher, I, Enderby, B, MacLean, M, McCormick, J, Paton, J Y, Wee, F, Thomas, H, Riding, K, Turner, S W, Williams, C & McIntosh, E & Lewis, S C 2015, ' Oxygen saturation targets in infants with bronchiolitis (BIDS): a double-blind, randomised, equivalence trial ', The Lancet, vol. 386, no. 9998, pp. 1041-1048 . https://doi.org/10.1016/S0140-6736(15)00163-4
Lancet (London, England)
Lancet (London, England)
Background: The American Academy of Pediatrics recommends a permissive hypoxaemic target for an oxygen saturation of 90% for children with bronchiolitis, which is consistent with the WHO recommendations for targets in children with lower respiratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50305b7c9a3c49d51922c90e52f1e3ca
https://hdl.handle.net/20.500.11820/78166e76-0ad6-4481-bff1-0c0618d39596
https://hdl.handle.net/20.500.11820/78166e76-0ad6-4481-bff1-0c0618d39596
Autor:
Vaida, Taminskiene, Somnath, Mukhopadhyay, Colin, Palmer, Anil, Mehta, Jon, Ayres, Arunas, Valiulis, Steve W, Turner
Publikováno v:
Pediatric pulmonology. 51(5)
Asthma affects children's quality of life (QoL) but factors associated with QoL are not well understood. Our hypothesis was that there are factors linked to QoL which are amenable to treatment or environmental modification.QoL was ascertained in a st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7170a00500a65bcc77fcf2cf3d6cb19
https://pubmed.ncbi.nlm.nih.gov/26669689
https://pubmed.ncbi.nlm.nih.gov/26669689
Autor:
Emily J, Pringle, Helen B, Richardson, David, Miller, Daniella S, Cornish, Graham S, Devereux, Garry M, Walsh, Steve W, Turner
Publikováno v:
Pediatric pulmonology. 47(12)
The present study was designed to test the hypothesis that airway epithelial cell (AEC) mediator release is similar in upper and lower airway AEC in children.Nasal and bronchial AEC were collected by brushings from children scheduled for general anes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7268d85351315edcad32ee981bf22079
https://pubmed.ncbi.nlm.nih.gov/23024038
https://pubmed.ncbi.nlm.nih.gov/23024038