The effect of different strains of Helicobacter pylori on platelet aggregation

Autor: Paul A Corcoran, John C Atherton, Steve W Kerrigan, Torkel Wadstrom, Frank E Murray, Richard M Peek, Desmond J Fitzgerald, Dermot M Cox, Michael F Byrne

Publikováno v: Canadian Journal of Gastroenterology, Vol 21, Iss 6, Pp 367-370 (2007)

BACKGROUND AND AIMS: Helicobacter pylori is the major causative agent in peptic ulcer disease and is strongly implicated in the development of gastric cancer. It has also been linked, less strongly, to cardiovascular disease. The mechanisms by which

Externí odkaz: https://doaj.org/article/997c1255dab14642b0d1d93494860954

Molecular Cross-Talk between Integrins and Cadherins Leads to a Loss of Vascular Barrier Integrity during SARS-CoV-2 Infection

Autor: Danielle Nader, Steve W. Kerrigan

Publikováno v: Viruses, Vol 14, Iss 5, p 891 (2022)

The vascular barrier is heavily injured following SARS-CoV-2 infection and contributes enormously to life-threatening complications in COVID-19. This endothelial dysfunction is associated with the phlogistic phenomenon of cytokine storms, thrombotic

Externí odkaz: https://doaj.org/article/c7375034f8184eda9fa321ea7c1abf42

Oral hygiene as a risk factor in infective endocarditis

Autor: Angela H. Nobbs, Richard G. Mears, Steve W. Kerrigan, Howard F. Jenkinson, Jennifer A Haworth

Publikováno v: Haworth, J A, Mears, R G, Jenkinson, H F, Kerrigan, S W & Nobbs, A H 2017, ' Oral hygiene as a risk factor in infective endocarditis ', Dental Update, vol. 44, no. 9, pp. 877-890 . < https://www.dental-update.co.uk/articleMatchListArticle.asp?aKey=1739 >
University of Bristol-PURE

There are many known associations between oral and systemic diseases. This review paper summarizes the proposed mechanisms underlying the links between dental disease and cardiovascular disease before introducing recent research regarding bacteria-pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f590dfa917f4243db83313a179f808aa
https://doi.org/10.12968/denu.2017.44.9.877

Clinical controversies in abdominal sepsis. Insights for critical care settings

Autor: Ignacio Martin-Loeches, Jan J. De Waele, Marc Leone, Massimo Sartelli, Steve W. Kerrigan, Jean-François Timsit, Sharon Einav, Luciano Cesar Pontes Azevedo

Publikováno v: Journal of Critical Care
Journal of Critical Care, WB Saunders, 2019, 53, pp.53-58. ⟨10.1016/j.jcrc.2019.05.023⟩
Journal of Critical Care, 2019, 53, pp.53-58. ⟨10.1016/j.jcrc.2019.05.023⟩

Sepsis is a deadly condition in which the outcome is associated with prompt and adequate recognition, intensive supportive care, antibiotic administration and source control. This last item makes abdominal sepsis a unique treatment challenge. Althoug

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0af339fd27a357779f74530e69c57c
https://hal-amu.archives-ouvertes.fr/hal-02481893

Concerted functions of Streptococcus gordonii surface proteins PadA and Hsa mediate activation of human platelets and interactions with extracellular matrix

Autor: Jennifer A, Haworth, Howard F, Jenkinson, Helen J, Petersen, Catherine R, Back, Jane L, Brittan, Steve W, Kerrigan, Angela H, Nobbs

Publikováno v: Haworth, J, Jenkinson, H, Petersen, H, Back, C, Brittan, J, Kerrigan, S & Nobbs, A 2017, ' Concerted functions of Streptococcus gordonii surface proteins PadA and Hsa mediate activation of human platelets and interactions with extracellular matrix ', Cellular Microbiology, vol. 19, no. 1, e12667 . https://doi.org/10.1111/cmi.12667
Cellular Microbiology

Summary A range of Streptococcus bacteria are able to interact with blood platelets to form a thrombus (clot). Streptococcus gordonii is ubiquitous within the human oral cavity and amongst the common pathogens isolated from subjects with infective en

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8ebc271d6e7d56d88802e7b7f4b748
https://research-information.bris.ac.uk/ws/files/107708244/Haworth_et_al_2017_Cellular_Microbiology.pdf