Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Steve Swenson"'
Autor:
Catalina Silva-Hirschberg, Hannah Hartman, Samantha Stack, Steve Swenson, Radu O. Minea, Michael A. Davitz, Thomas C. Chen, Axel H. Schönthal
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Background: Mycosis fungoides (MF) and Sézary syndrome (SS) are subtypes of primary cutaneous lymphomas and represent complex diseases regarding their physiopathology and management. Depending on the stage of the disease, different treatment regimen
Externí odkaz:
https://doaj.org/article/6f8923ff18ae4271b600c5369da99084
Autor:
Steve Swenson, Radu O. Minea, Cao Duc Tuan, Thu-Zan Thein, Thomas C. Chen, Francis S. Markland
Publikováno v:
Molecules, Vol 23, Iss 11, p 2918 (2018)
We developed a bacterial expression system to produce a recombinant disintegrin, vicrostatin (VCN), whose structure is based on a natural disintegrin isolated from southern copperhead snake venom. Our goal is to develop VCN for potential clinical tra
Externí odkaz:
https://doaj.org/article/0500811d701f4fb1977ce3622aa02ba3
Publikováno v:
Cancers; Volume 14; Issue 24; Pages: 6065
Many patients with acute myeloid leukemia (AML) are still dying from this disease. In the past, the alkylating agent temozolomide (TMZ) has been investigated for AML and found to be partially effective; however, the presence of O6-methylguanine DNA m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c734bef4da2db03bb3afe012672eb88d
Autor:
Axel H, Schönthal, Steve, Swenson, Phillip A, Bonney, Naveed, Wagle, Vincent F, Simmon, Anna J, Mathew, Kyle M, Hurth, Thomas C, Chen
Publikováno v:
Journal of Neurosurgery: Case Lessons. 4
BACKGROUND Intranasal delivery of NEO100, a pharmaceutical-grade version of the natural monoterpene perillyl alcohol (POH), is undergoing clinical phase IIa testing as a treatment for glioblastoma (GBM). However, so far there is no evidence that intr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::122f4fd18b234b267d87a1a610ac61af
https://doi.org/10.3171/case22215
https://doi.org/10.3171/case22215
Autor:
Nazleen Mohseni, Hee-Yeon Cho, Yong-Mi Kim, Thomas C. Chen, Axel H. Schönthal, Hye Na Kim, Radu O. Minea, Steve Swenson
Publikováno v:
Cancers
Cancers, Vol 13, Iss 3385, p 3385 (2021)
Volume 13
Issue 14
Cancers, Vol 13, Iss 3385, p 3385 (2021)
Volume 13
Issue 14
Simple Summary Many patients are still dying from acute myeloid leukemia (AML). Initial treatment of this blood-borne cancer consists of chemotherapy, usually with the agent cytarabine (AraC). However, the cancer cells can become drug resistant and u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d783fe30a1452a831e6c1f31c9f22d2
http://europepmc.org/articles/PMC8305595
http://europepmc.org/articles/PMC8305595
Autor:
Thu Zan Thein, Florence M. Hofman, Nagore I. Marín-Ramos, Neloni R Wijeratne, Hee-Yeon Cho, Steve Swenson, Thomas C. Chen, Weijun Wang, Jonathan E. Katz, Axel H. Schönthal
Publikováno v:
Neuro-oncology Advances
Background NEO212 is a novel small-molecule anticancer agent that was generated by covalent conjugation of the natural monoterpene perillyl alcohol (POH) to the alkylating agent temozolomide (TMZ). It is undergoing preclinical development as a therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad2eb9bca3c790dc31a7ca9424b0ced
https://pubmed.ncbi.nlm.nih.gov/33392507
https://pubmed.ncbi.nlm.nih.gov/33392507
Autor:
Florence M. Hofman, Kristen L. Chen, Catalina Silva-Hirschberg, Steve Swenson, Weijun Wang, Thomas C. Chen, Anupam Singh, Axel H. Schönthal
Publikováno v:
Oncotarget
Despite new treatments introduced over the past several years, metastatic melanoma remains difficult to cure. Although melanoma in situ (MIS) has better prognosis, it relies heavily on thorough surgical excision, where ill-defined margins can pose a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52a213c6ffb54a6fc07b09795059e74e
https://doi.org/10.18632/oncotarget.26443
https://doi.org/10.18632/oncotarget.26443
Autor:
Ryan Park, Steve Swenson, Li-Peng Yap, Francis S. Markland, Hossein Jadvar, Ivetta Vorobyova, Kai Chen
Publikováno v:
Amino Acids
A novel recombinant disintegrin, vicrostatin (VCN), displays high binding affinity to a broad range of human integrins in substantial competitive biological advantage over other integrin-based antagonists. In this study, we synthesized a new (64)Cu-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a970c33a868b383a37569faf56414599
https://europepmc.org/articles/PMC6881555/
https://europepmc.org/articles/PMC6881555/
Autor:
Axel H. Schönthal, Hannah Hartman, Steve Swenson, Thomas C. Chen, Michael A Davitz, Radu O. Minea, Catalina Silva-Hirschberg, Samantha Stack
Publikováno v:
Therapeutic Advances in Medical Oncology
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Therapeutic Advances in Medical Oncology, Vol 11 (2019)
Background: Mycosis fungoides (MF) and Sézary syndrome (SS) are subtypes of primary cutaneous lymphomas and represent complex diseases regarding their physiopathology and management. Depending on the stage of the disease, different treatment regimen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad097493650e1cc49c07c683f84953f
https://pubmed.ncbi.nlm.nih.gov/31839810
https://pubmed.ncbi.nlm.nih.gov/31839810
Autor:
Thomas C. Chen, Francis S. Markland, Cao Duc Tuan, Thu-Zan Thein, Radu O. Minea, Steve Swenson
Publikováno v:
Molecules, Vol 23, Iss 11, p 2918 (2018)
Molecules
Volume 23
Issue 11
Molecules
Volume 23
Issue 11
We developed a bacterial expression system to produce a recombinant disintegrin, vicrostatin (VCN), whose structure is based on a natural disintegrin isolated from southern copperhead snake venom. Our goal is to develop VCN for potential clinical tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f2075b42d9506657b9ead4ad9a57eec
https://www.mdpi.com/1420-3049/23/11/2918
https://www.mdpi.com/1420-3049/23/11/2918