Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Steve Steinway"'
Autor:
Maame Efua S. Sampah, Hannah Moore, Raheel Ahmad, Johannes Duess, Peng Lu, Carla Lopez, Steve Steinway, Daniel Scheese, Zachariah Raouf, Koichi Tsuboi, Jeffrey Ding, Connor Caputo, Madison McFarland, William B. Fulton, Sanxia Wang, Meghan Wang, Thomas Prindle, Vered Gazit, Deborah C. Rubin, Samuel Alaish, Chhinder P. Sodhi, David J. Hackam
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Short bowel syndrome (SBS) leads to severe morbidity and mortality. Intestinal adaptation is crucial in improving outcomes. To understand the human gene pathways associated with adaptation, we perform single-cell transcriptomic analysis of h
Externí odkaz:
https://doaj.org/article/dd561572beec437e9141bc2d050317a4
Autor:
Chhinder P. Sodhi, Raheel Ahmad, Hongpeng Jia, William B. Fulton, Carla Lopez, Andres J. Gonzalez Salazar, Asuka Ishiyama, Maame Sampah, Steve Steinway, Sanxia Wang, Thomas Prindle, Menghan Wang, David L. Steed, Howard Wessel, Ziv Kirshner, Larry R. Brown, Peng Lu, David J. Hackam
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 323:G265-G282
Necrotizing enterocolitis (NEC) is the leading cause of death from gastrointestinal disease in premature infants and is steadily rising in frequency. Patients who develop NEC have a very high mortality, illustrating the importance of developing novel
Publikováno v:
Cancer Research. 72:1087-1087
Hepatocellular carcinoma (HCC) patients with an active HGF/c-Met signaling pathway have a significantly worse prognosis. Although targeting strategies using MET tyrosine kinase inhibitors (TKI) are in Phase I/II testing for HCC, monotherapy using TKI
Publikováno v:
Gastroenterology. 140:S-14
Publikováno v:
Cancer Research. 71:1465-1465
Intro: Epithelial-to-mesenchymal transition (EMT) is drives metastasis in hepatocellular carcinoma (HCC). The micro-RNA 200 family blocks EMT by targeting Zeb1, a suppressors of E-cadherin. We investigated a dynamic network model of EMT to predict me