Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Steve Sideris"'
Autor:
Amanda H Kahn-Kirby, Akiko Amagata, Celine I Maeder, Janet J Mei, Steve Sideris, Yuko Kosaka, Andrew Hinman, Stephanie A Malone, Joel J Bruegger, Leslie Wang, Virna Kim, William D Shrader, Kevin G Hoff, Joey C Latham, Euan A Ashley, Matthew T Wheeler, Enrico Bertini, Rosalba Carrozzo, Diego Martinelli, Carlo Dionisi-Vici, Kimberly A Chapman, Gregory M Enns, William Gahl, Lynne Wolfe, Russell P Saneto, Simon C Johnson, Jeffrey K Trimmer, Matthew B Klein, Charles R Holst
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0214250 (2019)
BACKGROUND:Mitochondrial disease is a family of genetic disorders characterized by defects in the generation and regulation of energy. Epilepsy is a common symptom of mitochondrial disease, and in the vast majority of cases, refractory to commonly us
Externí odkaz:
https://doaj.org/article/8d6a4743a7c54e47b90913a261c70803
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 25K, Pharmacokinetic parameters of PKC412.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142f3edab434901c372ae690791ad537
https://doi.org/10.1158/2159-8290.22528442
https://doi.org/10.1158/2159-8290.22528442
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 528K, G�6976 inhibits EGFR mutant NSCLC cells independently of PKC inhibition.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d214e502c85c2ea75045588a3cbaf18c
https://doi.org/10.1158/2159-8290.22528460
https://doi.org/10.1158/2159-8290.22528460
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 142K, EGFR sequencing of the PC-9 ER clone.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b393712033171d96340c02807f748c6f
https://doi.org/10.1158/2159-8290.22528451.v1
https://doi.org/10.1158/2159-8290.22528451.v1
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 21K, Body weight measurement for EGFR T790M xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63abfacbcb1b8fee04af011cb0b6c75
https://doi.org/10.1158/2159-8290.22528445
https://doi.org/10.1158/2159-8290.22528445
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
XLSX file - 242K, Ambit kinome profiling with 0.5 μM G�6976.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::123fe209a3a1b72e9490e71f54d25c84
https://doi.org/10.1158/2159-8290.22528463.v1
https://doi.org/10.1158/2159-8290.22528463.v1
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 28K, PKC412 is the most selective EGFR T790M inhibitor tested versus EGFR wild-type.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ce89850a6f9e97571d24972b77a5f5
https://doi.org/10.1158/2159-8290.22528457
https://doi.org/10.1158/2159-8290.22528457
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
Approximately half of EGFR-mutant non–small cell lung cancer (NSCLC) patients treated with small-molecule EGFR kinase inhibitors develop drug resistance associated with the EGF receptor (EGFR) T790M “gatekeeper” substitution, prompting efforts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d720cf951858302908773bbba810a80
https://doi.org/10.1158/2159-8290.c.6545714.v1
https://doi.org/10.1158/2159-8290.c.6545714.v1
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
PDF file - 130K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7586586a1ec1c3fef87a4027bc16147a
https://doi.org/10.1158/2159-8290.22528436
https://doi.org/10.1158/2159-8290.22528436
Autor:
Jeff Settleman, Katerina Politi, Valentina Pirazzoli, Robert L. Yauch, Savita Ubhayakar, Hank La, Mark Merchant, Emily Chan, Shiva Malek, Steve Sideris, Xiaofen Ye, Lily Shao, Timothy P. Heffron, Gabriele Schaefer, Ho-June Lee
XLSX file - 109K, Tumor cell line profiling of G�6976 sensitivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de4a692e6b6b579b106c3c4b7ebe724
https://doi.org/10.1158/2159-8290.22528466
https://doi.org/10.1158/2159-8290.22528466