Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Steve Rowley"'
Autor:
Joonil Jung, Joon Sang Lee, Mark A. Dickson, Gary K. Schwartz, Axel Le Cesne, Andrea Varga, Rastilav Bahleda, Andrew J. Wagner, Edwin Choy, Maja J. de Jonge, Madelyn Light, Steve Rowley, Sandrine Macé, James Watters
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-7 (2016)
Pre-clinical studies have shown that TP53 mutations can account for acquired resistance to HDM2 antagonists. This study provides clinical evidence for the emergence of TP53mutations in circulating cell-free DNA, seen in 5 out of 20 de-differentiated
Externí odkaz:
https://doaj.org/article/260fdcaadef641d3801dbcc9cba2ac83
Autor:
Robert Gray, George W. Sledge, Paraic A. Kenny, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith A. Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
PDF file - 20K, Triple negative lower expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678128d80f481dd1f76cc3424094e403
https://doi.org/10.1158/1078-0432.22444041.v1
https://doi.org/10.1158/1078-0432.22444041.v1
Autor:
Robert Gray, George W. Sledge, Paraic A. Kenny, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith A. Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
Purpose: To conduct an exploratory analysis of the relationship between gene expression and recurrence in patients with operable triple-negative breast cancer (TNBC) treated with adjuvant doxorubicin-containing chemotherapy.Experimental Design: RNA w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2a1b307a4b9efefe8a0f54214a88417
https://doi.org/10.1158/1078-0432.c.6520047
https://doi.org/10.1158/1078-0432.c.6520047
Autor:
Robert Gray, George W. Sledge, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
Purpose: To perform an exploratory analysis of the relationship between gene expression and recurrence in operable hormone receptor (HR)–positive, human epidermal growth factor receptor 2 (HER2)–normal breast cancer patients treated with adjuvant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::643479c1683533945739aa25fe326a54
https://doi.org/10.1158/1078-0432.c.6517813
https://doi.org/10.1158/1078-0432.c.6517813
Autor:
Robert Gray, George W. Sledge, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
Supplementary Data from Relationship between Topoisomerase 2A RNA Expression and Recurrence after Adjuvant Chemotherapy for Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18650a49d46adff23b7ba64f40980162
https://doi.org/10.1158/1078-0432.22440490
https://doi.org/10.1158/1078-0432.22440490
Autor:
Robert Gray, George W. Sledge, Paraic A. Kenny, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith A. Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
XLS file - 31K, Patient characteristics by GRB7 expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aca49751437550bb5c121bed149fe42
https://doi.org/10.1158/1078-0432.22444047.v1
https://doi.org/10.1158/1078-0432.22444047.v1
Autor:
Robert Gray, George W. Sledge, Paraic A. Kenny, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith A. Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
PDF file - 72K, Box plots (with center line at the median and box edges at the quartiles) showing the raw distribution of GRB7, ERBB2, KRT19 and PHB expression for the triple negative (TN) subset, hormone receptor negative (HR-), HER2-positive (HER2+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb2edb95da7855efadefd5624c45c08
https://doi.org/10.1158/1078-0432.22444050.v1
https://doi.org/10.1158/1078-0432.22444050.v1
Autor:
Robert Gray, George W. Sledge, Paraic A. Kenny, Nancy E. Davidson, Silvana Martino, Lawrence N. Shulman, Edith A. Perez, Steve Rowley, Roberto Bugarini, Frederick L. Baehner, Sunil Badve, Diana Brassard, Steven Shak, Barrett H. Childs, Lori J. Goldstein, Joseph A. Sparano
PDF file - 49K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5366446e3763094a53327640bf938d7b
https://doi.org/10.1158/1078-0432.22444053.v1
https://doi.org/10.1158/1078-0432.22444053.v1
Autor:
Hannah L. Archibald, Steve Rowley, Faria M. Siddiqui, Sukhvinder Sidhu, Aaron N. Hata, Madelyn Light, Jeffrey A. Engelman, James Watters, Joon Sang Lee, Maria Gomez-Caraballo, Joonil Jung, Laurent Debussche, Ruslan I. Sadreyev, Fei Ji
Publikováno v:
Oncogene
There are currently no effective targeted therapies for KRAS mutant cancers. Therapeutic strategies that combine MEK inhibitors with agents that target apoptotic pathways may be a promising therapeutic approach. We investigated combining MEK and MDM2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::115f96e271e86bb97406eb44fcaa7ce3
https://doi.org/10.1038/onc.2017.258
https://doi.org/10.1038/onc.2017.258
Autor:
Bailin Zhang, Jing Zhang, Shujia Dai, Zhuyan Guo, Zhihu Ding, Jennifer Buell, Emma Wang, Steve Rowley, Jack Pollard, Dietmar Hoffmann, May Cindhuchao, Fangxian Sun, Jane Cheng, Alexei Protopopov, Stephane Poirier, Karen Wong, Amanda Lennon, Chandra Sekhar Pedamallu, Bridget Zhou, Joern Hopke, Laurent Debussche, Monsif Bouaboula, Malvika Koundinya
Publikováno v:
Cancer Research. 80:1377-1377
Despite the significant clinical success of the Immuno-Oncology treatment of microsatellite instability (MSI) patients, there remains huge unmet medical need because of mechanisms of resistance. Through an effort to analyze publicly available large-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29bea52ff38daf57e04f8636a6c9e16a
https://doi.org/10.1158/1538-7445.am2020-1377
https://doi.org/10.1158/1538-7445.am2020-1377