Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Steve R, Jordan"'
Autor:
Kate S, Ashton, Kristin L, Andrews, Marian C, Bryan, Marion C, Bryan, Jie, Chen, Kui, Chen, Michelle, Chen, Samer, Chmait, Michael, Croghan, Rod, Cupples, Christopher, Fotsch, Joan, Helmering, Steve R, Jordan, Robert J M, Kurzeja, Klaus, Michelsen, Lewis D, Pennington, Steve F, Poon, Glenn, Sivits, Gwyneth, Van, Steve L, Vonderfecht, Robert C, Wahl, Jiandong, Zhang, David J, Lloyd, Clarence, Hale, David J, St Jean
Publikováno v:
Journal of Medicinal Chemistry. 57:309-324
Small molecule activators of glucokinase have shown robust efficacy in both preclinical models and humans. However, overactivation of glucokinase (GK) can cause excessive glucose turnover, leading to hypoglycemia. To circumvent this adverse side effe
Autor:
Kate S. Ashton, Kristin L. Andrews, Marian C. Bryan, Jie Chen, Kui Chen, Michelle Chen, Samer Chmait, Michael Croghan, Rod Cupples, Christopher Fotsch, Joan Helmering, Steve R. Jordan, Robert J. M. Kurzeja, Klaus Michelsen, Lewis D. Pennington, Steve F. Poon, Glenn Sivits, Gwyneth Van, Steve L. Vonderfecht, Robert C. Wahl, Jiandong Zhang, David J. Lloyd, Clarence Hale, David J. St. Jean
Publikováno v:
Journal of Medicinal Chemistry. 57:2820-2820