Výsledky vyhledávání - "Steve P. Bernier"

Akademický článek

Completion of draft bacterial genomes by long-read sequencing of synthetic genomic pools

Autor: Hooman Derakhshani, Steve P. Bernier, Victoria A. Marko, Michael G. Surette

Publikováno v: BMC Genomics, Vol 21, Iss 1, Pp 1-11 (2020)

Abstract Background Illumina technology currently dominates bacterial genomics due to its high read accuracy and low sequencing cost. However, the incompleteness of draft genomes generated by Illumina reads limits their application in comprehensive g

Externí odkaz: https://doaj.org/article/0120bb1e767144ddb08f701154e52fa8

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Akademický článek

Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Gluten triggers celiac disease in genetically predisposed individuals, but additional unknown mechanisms are required. Here, the authors show that proteases from Pseudomonas aeruginosa can modulate inflammatory pathways that are relevant to the devel

Externí odkaz: https://doaj.org/article/87da3a2758a84144a45120e2dbe4b18e

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Akademický článek

Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to ColitisSummary

Autor: Yun Han Kwon, Huaqing Wang, Emmanuel Denou, Jean-Eric Ghia, Laura Rossi, Michelle E. Fontes, Steve P. Bernier, Md. Sharif Shajib, Suhrid Banskota, Stephen M. Collins, Michael G. Surette, Waliul I. Khan

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 709-728 (2019)

Background & Aims: Serotonin (5-hydroxytryptamine [5-HT]) is synthesized mainly within enterochromaffin (EC) cells in the gut, and tryptophan hydroxylase 1 (Tph1) is the rate-limiting enzyme for 5-HT synthesis in EC cells. Accumulating evidence sugge

Externí odkaz: https://doaj.org/article/277aef30894e466383b247fb23fca29b

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Akademický článek

Cyanide toxicity to Burkholderia cenocepacia is modulated by polymicrobial communities and environmental factors

Autor: Steve P. Bernier, Matthew L. Workentine, Xiang eLi, Nathan A. Magarvey, George A. O'Toole, Michael G Surette

Publikováno v: Frontiers in Microbiology, Vol 7 (2016)

Microbes within polymicrobial communities can establish positive and negative interactions that have the potential to influence the overall behaviour of the community. Pseudomonas aeruginosa and species of the Burkholderia cepacia complex (Bcc) can c

Externí odkaz: https://doaj.org/article/3051991078f444dea93af63447be9e57

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Akademický článek

Aerial Exposure to the Bacterial Volatile Compound Trimethylamine Modifies Antibiotic Resistance of Physically Separated Bacteria by Raising Culture Medium pH

Autor: Sylvie Létoffé, Bianca Audrain, Steve P. Bernier, Muriel Delepierre, Jean-Marc Ghigo

Publikováno v: mBio, Vol 5, Iss 1 (2014)

ABSTRACT Bacteria release a wide diversity of small bioactive molecules that often correspond to secondary metabolites. Among them, volatile molecules produced under various growth conditions were shown to mediate cross-kingdom interactions with plan

Externí odkaz: https://doaj.org/article/2bfc0bc928c74163b3af99f38089f8ba

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Modulation of Gut Microbiota Composition by Serotonin Signaling Influences Intestinal Immune Response and Susceptibility to Colitis

Autor: Laura Rossi, Waliul I. Khan, Jean-Eric Ghia, Steve P. Bernier, Stephen M. Collins, Emmanuel Denou, Suhrid Banskota, Md. Sharif Shajib, Michelle E. Fontes, Huaqing Wang, Yun Han Kwon, Michael G. Surette

Publikováno v: Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 4, Pp 709-728 (2019)
Cellular and Molecular Gastroenterology and Hepatology

Background & Aims Serotonin (5-hydroxytryptamine [5-HT]) is synthesized mainly within enterochromaffin (EC) cells in the gut, and tryptophan hydroxylase 1 (Tph1) is the rate-limiting enzyme for 5-HT synthesis in EC cells. Accumulating evidence sugges

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d7b958a4788fee643381de67358945
https://doi.org/10.1016/j.jcmgh.2019.01.004

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Completion of draft bacterial genomes by long-read sequencing of synthetic genomic pools

Autor: Michael G. Surette, Victoria A. Marko, Hooman Derakhshani, Steve P. Bernier

Publikováno v: BMC Genomics
BMC Genomics, Vol 21, Iss 1, Pp 1-11 (2020)

Background Illumina technology currently dominates bacterial genomics due to its high read accuracy and low sequencing cost. However, the incompleteness of draft genomes generated by Illumina reads limits their application in comprehensive genomics a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9788d787c437b6e339d5d57b25c4d313
https://pubmed.ncbi.nlm.nih.gov/32727443

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Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2019, 10 (1), ⟨10.1038/s41467-019-09037-9⟩
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-09037-9⟩
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Nature Communications 1 (10), . (2019)

Microbe-host interactions are generally homeostatic, but when dysfunctional, they can incite food sensitivities and chronic diseases. Celiac disease (CeD) is a food sensitivity characterized by a breakdown of oral tolerance to gluten proteins in gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f7339d9babb57ded865cdb3f6de8dc6
https://hal.inrae.fr/hal-02626218/document

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Duodenal Bacteria From Patients With Celiac Disease and Healthy Subjects Distinctly Affect Gluten Breakdown and Immunogenicity

Autor: Elena F. Verdu, Steve P. Bernier, Alexandra R. Herrán, Alberto Caminero, Chad W. Johnston, Amy K. Russell, Heather J. Galipeau, Jennifer Jury, Michael G. Surette, Justin L. McCarville, Javier Casqueiro, Detlef Schuppan, Jason A. Tye-Din, Nathan A. Magarvey

Publikováno v: Gastroenterology. 151:670-683

Background & Aims Partially degraded gluten peptides from cereals trigger celiac disease (CD), an autoimmune enteropathy occurring in genetically susceptible persons. Susceptibility genes are necessary but not sufficient to induce CD, and additional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::521dac7de57936f3b54cbdbc6edc2e26
https://doi.org/10.1053/j.gastro.2016.06.041

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The Mla Pathway Plays an Essential Role in the Intrinsic Resistance of Burkholderia cepacia Complex Species to Antimicrobials and Host Innate Components

Autor: Steve P. Bernier, Susie Son, Michael G. Surette

Publikováno v: Journal of Bacteriology. 200

Antibiotic resistance is a threat to our modern society, and new strategies leading to the identification of new molecules or targets to combat multidrug-resistant pathogens are needed. Species of the genus Burkholderia, including the Burkholderia ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec0b293b3e2291e033d13da527417fa0
https://doi.org/10.1128/jb.00156-18

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