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Autor:
Maia M. Cherney, Richard A. Pfuetzner, John W. Little, Mark Paetzel, Yu Luo, Natalie C. J. Strynadka, Steve Mosimann, Elizabeth A. Frey, Baek Kim
Publikováno v:
Cell. 106:585-594
LexA repressor undergoes a self-cleavage reaction. In vivo, this reaction requires an activated form of RecA, but it occurs spontaneously in vitro at high pH. Accordingly, LexA must both allow self-cleavage and yet prevent this reaction in the absenc