Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Steve McClellan"'
Autor:
Jianfeng Li, Silvia Garavaglia, Zhaofeng Ye, Andrea Moretti, Olga V. Belyaeva, Alison Beiser, Md Ibrahim, Anna Wilk, Steve McClellan, Alla V. Klyuyeva, Kelli R. Goggans, Natalia Y. Kedishvili, E. Alan Salter, Andrzej Wierzbicki, Marie E. Migaud, Steven J. Mullett, Nathan A. Yates, Carlos J. Camacho, Menico Rizzi, Robert W. Sobol
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Using in silico modeling, Li et al. identify a selective inhibitor for aldehyde dehydrogenase isoform ALDH1A3, which is highly expressed in mesenchymal glioma stem cells and therefore a potential drug target. They solve the structure of the ALDH1A3/M
Externí odkaz:
https://doaj.org/article/d4ab4bd6ea5d4fe5ac3e294cb177d517
Autor:
Erhong Meng, Aparna Mitra, Kaushlendra Tripathi, Michael A Finan, Jennifer Scalici, Steve McClellan, Luciana Madeira da Silva, Eddie Reed, Lalita A Shevde, Komaraiah Palle, Rodney P Rocconi
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107142 (2014)
Aldehyde dehydrogenase (ALDH) expressing cells have been characterized as possessing stem cell-like properties. We evaluated ALDH+ ovarian cancer stem cell-like properties and their role in platinum resistance.Isogenic ovarian cancer cell lines for p
Externí odkaz:
https://doaj.org/article/744a1d9d22674ad3ab032a5f867ba08e
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13213 (2010)
BACKGROUND: The presence of conceptus alloantigens necessitates changes in maternal immune function. One player in this process may be the macrophage. In the cow, there is large-scale recruitment of macrophages expressing CD68 and CD14 to the uterine
Externí odkaz:
https://doaj.org/article/0f12b563254d40988514fd211e7b8f89
Publikováno v:
Journal of Manipulative and Physiological Therapeutics. 44:372-377
Objective The purpose of this study was to evaluate the relationship between treatment escalation and spinal manipulation in a retrospective cohort of people diagnosed with musculoskeletal disorders of the cervical spine. Methods We used retrospectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3798ca4024ef9cb203e3093134cb1906
https://doi.org/10.1016/j.jmpt.2021.03.001
https://doi.org/10.1016/j.jmpt.2021.03.001
Autor:
Steve McClellan
Publikováno v:
Towards a New Political Economy of Agriculture ISBN: 9780429269493
Towards a New Political Economy of Agriculture
Towards a New Political Economy of Agriculture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::686b54c9e784eaf225b6582fd90704c3
https://doi.org/10.4324/9780429269493-14
https://doi.org/10.4324/9780429269493-14
Autor:
Jianfeng, Li, Kate, M Saville, Md, Ibrahim, Xuemei, Zeng, Steve, McClellan, Anusha, Angajala, Alison, Beiser, Joel F, Andrews, Mai, Sun, Christopher A, Koczor, Jennifer, Clark, Faisal, Hayat, Mikhail V, Makarov, Anna, Wilk, Nathan A, Yates, Marie E, Migaud, Robert W, Sobol
Publikováno v:
NAR Cancer
Elevated expression of the DNA damage response proteins PARP1 and poly(ADP-ribose) glycohydrolase (PARG) in glioma stem cells (GSCs) suggests that glioma may be a unique target for PARG inhibitors (PARGi). While PARGi-induced cell death is achieved w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc7420e3ec2c356d6b1e84245cd0b3ed
https://pubmed.ncbi.nlm.nih.gov/34806016
https://pubmed.ncbi.nlm.nih.gov/34806016
Autor:
Adam B. Keeton, Rebecca Barber, Antonio Ward, Ileana V. Aragon, Alla Musiyenko, Joel Andrews, Wito Richter, Annelise M. Wilhite, Steve McClellan, Kevin Lee, Gary A. Piazza, Luciana Madeira da Silva, Jennifer Scalici, Elaine Gavin, Kristy L. Berry, Xi Chen
Publikováno v:
Cancer Research. 81:1213-1213
Objective: A leading theory for ovarian carcinogenesis proposes that the inflammation associated with incessant ovulation is a driver of oncogenesis. Consistent with this theory, epidemiological studies have shown that nonsteroidal anti-inflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffb0460fddc46028d6d5cb7dca57bc4f
https://doi.org/10.1158/1538-7445.am2021-1213
https://doi.org/10.1158/1538-7445.am2021-1213
Autor:
Kevin F. Spratt, Ronald Donelson, Eric Gatmaitan, J Mark Miller, W Steve McClellan, Richard Gray
Publikováno v:
J Man Manip Ther
Objectives: The escalating cost of low back pain (LBP) care has not improved outcomes. Our purpose: to compare costs between LBP care guided by a quality-assured mechanical assessment (MC) and usual community care (CC). Study Design: Administrative c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2009aed6b26d56cf1cb80226443795d4
https://pubmed.ncbi.nlm.nih.gov/31104572
https://pubmed.ncbi.nlm.nih.gov/31104572
Autor:
Seema Singh, Arun Bhardwaj, Bin Wang, Sanjeev K. Srivastava, Sumit Arora, Nikhil Tyagi, Steve McClellan, Joel Andrews, Ajay P. Singh
Publikováno v:
British Journal of Cancer
Background: Previously, miR-345 was identified as one of the most significantly downregulated microRNAs in pancreatic cancer (PC); however, its functional significance remained unexplored. Methods: miR-345 was overexpressed in PC cells by stable tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d61334d19a8d9a2ede1e30692b159d9
https://doi.org/10.1038/bjc.2015.252
https://doi.org/10.1038/bjc.2015.252
Autor:
Steve McClellan, Kenya Honda, Johnny Lightcap, Amit Reddy, Andrew Y. Koh, Arthur E. Frankel, Rose L. Szabady, Bruce L. Roberts, Sachin Kumar Deshmukh
Publikováno v:
Journal of Clinical Oncology. 37:e14195-e14195
e14195 Background: Immune checkpoint inhibitor therapy, ICT, achieves remissions in melanoma patients but factors modulating response are not well defined. Our group (Frankel et al. Neoplasia 2017) and others have identified specific gut microbiota a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60a20476b0733316cbbb47b5aa2df9fe
https://doi.org/10.1200/jco.2019.37.15_suppl.e14195
https://doi.org/10.1200/jco.2019.37.15_suppl.e14195