Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Steve Mangos"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2497 (2024)
The field of nephrology has recently directed a considerable amount of attention towards the stimulator of interferon genes (STING) molecule since it appears to be a potent driver of chronic kidney disease (CKD). STING and its activator, the cyclic G
Externí odkaz:
https://doaj.org/article/9ad7653551fa48a5aa078d21e50b28e8
Autor:
Shivangi Agarwal, Kwi Hye Koh, Nicholas J. Tardi, Chuang Chen, Ranadheer Reddy Dande, Joao Pedro WerneckdeCastro, Yashwanth Reddy Sudhini, Cristina Luongo, Domenico Salvatore, Beata Samelko, Mehmet M. Altintas, Steve Mangos, Antonio Bianco, Jochen Reiser
Publikováno v:
EBioMedicine, Vol 72, Iss , Pp 103617- (2021)
ABSTRACT: Background: Nephrotic syndrome (NS) is associated with kidney podocyte injury and may occur as part of thyroid autoimmunity such as Graves’ disease. Therefore, the present study was designed to ascertain if and how podocytes respond to an
Externí odkaz:
https://doaj.org/article/ac26f616b0024f88b24df376bf577abf
Autor:
Xueping Fan, Qinggang Li, Anna Pisarek-Horowitz, Hila Milo Rasouly, Xiangling Wang, Ramon G. Bonegio, Hang Wang, Margaret McLaughlin, Steve Mangos, Raghu Kalluri, Lawrence B. Holzman, Iain A. Drummond, Dennis Brown, David J. Salant, Weining Lu
Publikováno v:
Cell Reports, Vol 2, Iss 1, Pp 52-61 (2012)
Robo2 is the cell surface receptor for the repulsive guidance cue Slit and is involved in axon guidance and neuronal migration. Nephrin is a podocyte slit-diaphragm protein that functions in the kidney glomerular filtration barrier. Here, we report t
Externí odkaz:
https://doaj.org/article/1211909f88b1494e88ef9ad6bb5cba52
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0115639 (2015)
Actin microridges form labyrinth like patterns on superficial epithelial cells across animal species. This highly organized assembly has been implicated in mucus retention and in the mechanical structure of mucosal surfaces, however the mechanisms th
Externí odkaz:
https://doaj.org/article/6bfe309d7aaf40d1838765829adfb898
Autor:
Aleksandr Vasilyev, Yan Liu, Sudha Mudumana, Steve Mangos, Pui-Ying Lam, Arindam Majumdar, Jinhua Zhao, Kar-Lai Poon, Igor Kondrychyn, Vladimir Korzh, Iain A Drummond
Publikováno v:
PLoS Biology, Vol 7, Iss 1, p e9 (2009)
Tissue organization in epithelial organs is achieved during development by the combined processes of cell differentiation and morphogenetic cell movements. In the kidney, the nephron is the functional organ unit. Each nephron is an epithelial tubule
Externí odkaz:
https://doaj.org/article/22287944532b43d5a94406c17a9a43b5
Autor:
Onur K. Polat, Elena Isaeva, Yashwanth R. Sudhini, Brenna Knott, Ke Zhu, Manuel Noben, Varsha Suresh Kumar, Nicole Endlich, Steve Mangos, Tejasree Vallapu Reddy, Beata Samelko, Changli Wei, Mehmet M. Altintas, Stuart E. Dryer, Sanja Sever, Alexander Staruschenko, Jochen Reiser
Publikováno v:
Kidney International. 103:1056-1062
Autor:
Andre Paredes, Panayiotis Tsiampas, Steve Mangos, Rachana Patil, Timothy Koh, Michael Donoghue, Enrico Benedetti, Amelia Bartholomew
Publikováno v:
Medical Research Archives. 10
Background: Neutrophils participate in a cooperative defense strategy with macrophages following tissue injury. Application of low dose electromagnetic radiation via 635 nm wavelength can enhance macrophage recruitment to the wound, decrease tissue l
Autor:
Steve Mangos, Domenico Salvatore, Jochen Reiser, Ranadheer Reddy Dande, Kwi Hye Koh, Antonio C. Bianco, Chuang Chen, Joao Pedro WerneckdeCastro, Yashwanth Reddy Sudhini, Cristina Luongo, Nicholas J. Tardi, Beata Samelko, Shivangi Agarwal, Mehmet M. Altintas
Publikováno v:
EBioMedicine
EBioMedicine, Vol 72, Iss, Pp 103617-(2021)
EBioMedicine, Vol 72, Iss, Pp 103617-(2021)
Background: Nephrotic syndrome (NS) is associated with kidney podocyte injury and may occur as part of thyroid autoimmunity such as Graves’ disease. Therefore, the present study was designed to ascertain if and how podocytes respond to and regulate
Autor:
Vasil Peev, Eunsil Hahm, Hyun Lee, Nicholas J. Tardi, Ranadheer R. Dande, Mehmet M. Altintas, Cao Yanxia, Beata Samelko, Kamalika Mukherjee, Steve Mangos, Jochen Reiser, Vincent P. Schmitz, Kwi Hye Koh, Ha Won Lee, David Cimbaluk
Publikováno v:
Journal of Clinical Investigation. 129:1713-1726
Soluble urokinase receptor (suPAR) is a circulatory molecule that activates αvβ3 integrin on podocytes, causes foot process effacement, and contributes to proteinuric kidney disease. While active integrin can be targeted by antibodies and small mol
Autor:
David Benavidez, Andre D. Paredes, Steve Mangos, Enrico Benedetti, Rachana Patil, Michael Donoghue, Amelia Bartholomew, Jun Cheng
Publikováno v:
Photobiomodulation, Photomedicine, and Laser Surgery. 37:45-52
Objective: The aim of our study was to quantify the effect of doses delivered by a He:Ne laser on individual macrophage kinetics, tissue oxidative stress, and wound closure using real-time...