Zobrazeno 1 - 10
of 111
pro vyhledávání: '"Steve Lawrence"'
Autor:
Laura Sibley, Charlotte Sarfas, Alexandra L. Morrison, Jessica Williams, Konstantinos Gkolfinos, Adam Mabbutt, William Eckworth, Steve Lawrence, Mike Dennis, Andrew White, Sally Sharpe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The BCG vaccine is given to millions of children globally but efficacy wanes over time and differences in the immune systems between infants and adults can influence vaccine efficacy. To this end, 34 rhesus macaques were vaccinated with BCG
Externí odkaz:
https://doaj.org/article/2c2a236866d34cea8189ad6904100b82
Autor:
Andrew D. White, Andy C. Tran, Laura Sibley, Charlotte Sarfas, Alexandra L. Morrison, Steve Lawrence, Mike Dennis, Simon Clark, Sirine Zadi, Faye Lanni, Emma Rayner, Alastair Copland, Peter Hart, Gil Reynolds Diogo, Matthew J. Paul, Miyoung Kim, Fergus Gleeson, Francisco J. Salguero, Mahavir Singh, Matthias Stehr, Simon M. Cutting, Juan I. Basile, Martin E. Rottenberg, Ann Williams, Sally A. Sharpe, Rajko Reljic
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Tuberculosis remains a major health threat globally and a more effective vaccine than the current Bacillus Calmette Guerin (BCG) is required, either to replace or boost it. The Spore-FP1 mucosal vaccine candidate is based on the fusion protein of Ag8
Externí odkaz:
https://doaj.org/article/5d6971450abd4bfbb64716fb58efad30
Autor:
Alexandra L. Morrison, Charlotte Sarfas, Laura Sibley, Jessica Williams, Adam Mabbutt, Mike J. Dennis, Steve Lawrence, Andrew D. White, Mark Bodman-Smith, Sally A. Sharpe
Publikováno v:
Vaccines, Vol 11, Iss 10, p 1604 (2023)
Intravenously (IV) delivered BCG provides superior tuberculosis (TB) protection compared with the intradermal (ID) route in non-human primates (NHPs). We examined how γδ T cell responses changed in vivo after IV BCG vaccination of NHPs, and whether
Externí odkaz:
https://doaj.org/article/8cdbb2b4d36443c98f5fbd9003c1ea1c
Autor:
Charlotte Sarfas, Andrew D. White, Laura Sibley, Alexandra L. Morrison, Jennie Gullick, Steve Lawrence, Mike J. Dennis, Philip D. Marsh, Helen A. Fletcher, Sally A. Sharpe
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
In many countries where tuberculosis (TB) is endemic, the Bacillus Calmette–Guérin (BCG) vaccine is given as close to birth as possible to protect infants and children from severe forms of TB. However, BCG has variable efficacy and is not as effec
Externí odkaz:
https://doaj.org/article/23a524431d8548a983dc1bcc98994a67
Autor:
Laura Sibley, Charlotte Sarfas, Alexandra L Morrison, Jessica J Williams, Konstantinos Gkolfinos, Adam Mabbutt, William Eckworth, Steve Lawrence, Mike Dennis, Andrew D White, Sally Sharpe
The BCG vaccine is given to millions of children globally but efficacy wanes over time and differences in the immune systems between infants and adults can influence vaccine efficacy. To this end, 34 rhesus macaques were vaccinated with BCG within se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8cf723a40aea8523354c2b471cb88c2
https://doi.org/10.21203/rs.3.rs-2890669/v1
https://doi.org/10.21203/rs.3.rs-2890669/v1
Publikováno v:
Oxoniensia 87 ISBN: 9781805430162
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::633446e8cc3fd430c07c905db5e32539
https://doi.org/10.2307/jj.1431187.13
https://doi.org/10.2307/jj.1431187.13
Relative age effects (RAEs) are a well-known phenomenon within youth sports. Although research consistently shows participation biases across the youth sporting domain, there appears to be a paucity of research focusing on interventions aimed at miti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44db42f3ff46b9adb13c35712438b206
https://doi.org/10.4324/9781003163572-10
https://doi.org/10.4324/9781003163572-10
Autor:
Stan Lun, C. Joy McIntosh, Jennifer L. Juengel, Steve Lawrence, Kenneth P. McNatty, Andrea Western
Publikováno v:
Biology of Reproduction. 79:889-896
Bone morphogenetic protein 15 (BMP15) and growth and differentiation factor 9 (GDF9) are secreted by the mammalian oocyte and are essential for ovarian follicular development, ovulation, and fertility. However, the secreted forms of the BMP15 and GDF
Autor:
Andrea Western, Karen L Reader, Kenneth P. McNatty, Sara J. Edwards, Jennifer L. Juengel, Stan Lun, Steve Lawrence
Publikováno v:
Endocrinology. 149:1026-1030
Growth and differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15, GDF9B) are oocyte-derived proteins essential for the growth and function of ovarian follicles. Moreover, ovine (o) GDF9 and oBMP15 cooperate to increase both (3)H-th
Publikováno v:
2015 Joint Rail Conference.
New and expanded passenger rail projects must deliver dependable scheduled service with affordable operations and maintenance (O&M) costs. Reliability, Availability, and Maintainability (RAM) characteristics of equipment, facilities, and rolling stoc