Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Steve K, Cho"'
Autor:
Hyunji Moon, Chanhyuk Min, Gayoung Kim, Deokhwan Kim, Kwanhyeong Kim, Sang-Ah Lee, Byeongjin Moon, Susumin Yang, Juyeon Lee, Seung-Joo Yang, Steve K. Cho, Gwangrog Lee, Chang Sup Lee, Chul-Seung Park, Daeho Park
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Calcium flux must be carefully controlled during the phagocytosis of apoptotic cells (efferocytosis), although how this occurs is not fully understood. Here, the authors show that the Cereblon E3 ligase regulates Orai1 degradation and subsequently SO
Externí odkaz:
https://doaj.org/article/e974b64c64804ac5944f1149649c6f51
Autor:
Dinesh K. Singh, Rahul K. Kollipara, Vamsidara Vemireddy, Xiao-Li Yang, Yuxiao Sun, Nanda Regmi, Stefan Klingler, Kimmo J. Hatanpaa, Jack Raisanen, Steve K. Cho, Shyam Sirasanagandla, Suraj Nannepaga, Sara Piccirillo, Tomoyuki Mashimo, Shan Wang, Caroline G. Humphries, Bruce Mickey, Elizabeth A. Maher, Hongwu Zheng, Ryung S. Kim, Ralf Kittler, Robert M. Bachoo
Publikováno v:
Cell Reports, Vol 18, Iss 4, Pp 961-976 (2017)
Efforts to identify and target glioblastoma (GBM) drivers have primarily focused on receptor tyrosine kinases (RTKs). Clinical benefits, however, have been elusive. Here, we identify an SRY-related box 2 (SOX2) transcriptional regulatory network that
Externí odkaz:
https://doaj.org/article/584c70e23319436aa0e06b23b2f7fe46
Publikováno v:
Canadian Journal of Gastroenterology and Hepatology, Vol 2019 (2019)
Background. Hepatocellular carcinoma (HCC) is one of the most common malignant cancers with a poor prognosis. Several commonly investigated immunohistochemical markers in resected HCC have potential prognostic value, but the prognostic utility of p53
Externí odkaz:
https://doaj.org/article/41a38ee0b95e44f98f892d5ade5c0eb1
Autor:
Robert M. Bachoo, Jerry W. Shay, Woodring E. Wright, Bruce E. Mickey, Christopher J. Madden, Kimmo J. Hatanpaa, Elizabeth A. Maher, Brian M. Mcellin, Steve K. Cho, Calin O. Marian
Supplementary Data from The Telomerase Antagonist, Imetelstat, Efficiently Targets Glioblastoma Tumor-Initiating Cells Leading to Decreased Proliferation and Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae43f6e6e24372b8857fed87bf6684d
https://doi.org/10.1158/1078-0432.22446050.v1
https://doi.org/10.1158/1078-0432.22446050.v1
Autor:
Robert M. Bachoo, Jerry W. Shay, Woodring E. Wright, Bruce E. Mickey, Christopher J. Madden, Kimmo J. Hatanpaa, Elizabeth A. Maher, Brian M. Mcellin, Steve K. Cho, Calin O. Marian
Purpose: Telomerase activity is one of the hallmarks of cancer and is a highly relevant therapeutic target. The effects of a novel human telomerase antagonist, imetelstat, on primary human glioblastoma (GBM) tumor-initiating cells were investigated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f35ea0c368c2cfe3b9f8729222e836a
https://doi.org/10.1158/1078-0432.c.6520634.v1
https://doi.org/10.1158/1078-0432.c.6520634.v1
Autor:
Samir M. Iqbal, Andrew D. Ellington, Robert Bachoo, Steve K. Cho, Na Li, Young-tae Kim, Yuan Wan
Exposing rare but highly malignant tumor cells that migrate from the primary tumor mass into adjacent tissue(s) or circulate in the bloodstream is critical for early detection and effective intervention(s). Here, we report on an aptamer-based strateg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c65906a2bccad09e9aedbb2e0b369a7
https://doi.org/10.1158/0008-5472.c.6500835.v1
https://doi.org/10.1158/0008-5472.c.6500835.v1
Autor:
Samir M. Iqbal, Andrew D. Ellington, Robert Bachoo, Steve K. Cho, Na Li, Young-tae Kim, Yuan Wan
Supplementary Video 1 from Surface-Immobilized Aptamers for Cancer Cell Isolation and Microscopic Cytology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b7919fd2fbc9b2abfeba390e35aca66
https://doi.org/10.1158/0008-5472.22384299
https://doi.org/10.1158/0008-5472.22384299
Autor:
Chang Woo Park, Seungje Jeon, Seong‐Hoon Kwon, Jun‐Hyung Jung, Jung Eun Seol, Chul‐Seung Park, Steve K. Cho, Do‐Kyeong Ko
Publikováno v:
Journal of Biophotonics. 16
By utilizing a multimodal nonlinear optical system that combines coherent anti-Stokes Raman scattering and second harmonic generation to investigate biological characteristics of dermal tissues ex vivo, we demonstrate the potential feasibility of usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::919aa16904a09136c4547e0d8f8e8d79
https://doi.org/10.1002/jbio.202200139
https://doi.org/10.1002/jbio.202200139
Autor:
Koushik Guchhait, Hyeon Seung Yoon, Seungheon Shin, Hyun-Su An, Hye Seung Nam, Francisco D. Yanqui-Rivera, Samara M. Oña, Miguel Á. Mendez, Seokjae Park, Eun-Kyoung Kim, Jong Yeon Hwang, Jee-Young Han, Doo Yong Chung, Daeho Park, Su-Geun Yang, Chul-Seung Park, Steve K. Cho
Publikováno v:
Cancer Research. 83:LB157-LB157
As the third enzyme of the pentose phosphate pathway (PPP), abnormally elevated levels of 6-phosphogluconate dehydrogenase (6PGD) have been documented in various human cancers. We demonstrate that reduced cereblon (CRBN) protein expression is the und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b845a2efcb86523a5c9efbf1d062904b
https://doi.org/10.1158/1538-7445.am2023-lb157
https://doi.org/10.1158/1538-7445.am2023-lb157
Autor:
Hong Phuong, Nguyen, Seungheon, Shin, Kyung-Ju, Shin, Phuong Hoa, Tran, Hyungsun, Park, Quang, De Tran, Mi-Hyun, No, Ji Su, Sun, Ki Woo, Kim, Hyo-Bum, Kwak, Seongju, Lee, Steve K, Cho, Su-Geun, Yang
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1870:119384
Adverse effects of spaceflight on the human body are attritubuted to microgravity and space radiation. One of the most sensitive organs affected by them is the eye, particularly the retina. The conditions that astronauts suffer, such as visual acuity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed3e162a378f3c10fa39457b761f4d3a
https://doi.org/10.1016/j.bbamcr.2022.119384
https://doi.org/10.1016/j.bbamcr.2022.119384