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pro vyhledávání: '"Steve J. Sullivan"'
Publikováno v:
Molecular pain. 18
Neurostimulation therapies are frequently used in patients with chronic pain conditions. They emerged from Gate Control Theory (GCT), which posits that Aβ-fiber activation recruits superficial dorsal horn (SDH) inhibitory networks to “close the ga
Autor:
Steve J. Sullivan, Andrei D. Sdrulla
Publikováno v:
J Neurosci
The superficial dorsal horn (SDH) of the spinal cord represents the first site of integration between innocuous and noxious somatosensory stimuli. According to gate control theory, diverse populations of excitatory and inhibitory interneurons within
Autor:
Robert F. Miller, Manuel Esguerra, Ryuichi Konno, Steve J. Sullivan, Eric C. Gustafson, Catherine W. Morgans, Merve Tekmen
Publikováno v:
Journal of Neurophysiology. 110:2718-2726
d-serine is present in the vertebrate retina and serves as a coagonist for the N-methyl-d-aspartate (NMDA) receptors of ganglion cells. Although the enzyme d-amino acid oxidase (DAO) has been implicated as a pathway for d-serine degradation, its role
Autor:
Steve J. Sullivan, Robert F. Miller
Publikováno v:
Journal of Neurophysiology. 108:1044-1051
NMDA receptor (NMDAR) activation requires coincident binding of the excitatory neurotransmitter glutamate and a coagonist, either glycine or d-serine. Changes in NMDAR currents during neural transmission are typically attributed to glutamate release
Autor:
Manuel Esguerra, Gabriel E. Romero, Steve J. Sullivan, Joseph T. Coyle, Robert J. Wickham, Robert F. Miller
Publikováno v:
The Journal of Physiology. 589:5997-6006
Glycine and/or D-serine are obligatory coagonists of the N-methyl-D-aspartate receptor (NMDAR). Serine racemase, the D-serine-synthesizing enzyme, is expressed by astrocytes and Muller cells of the retina, but little is known about its role in retina
Autor:
Robert F. Miller, Steve J. Sullivan
Publikováno v:
Journal of Neurochemistry. 115:1681-1689
J. Neurochem. (2010) 115, 1681–1689. Abstract The N-methyl-d-aspartate receptor (NMDAR) co-agonist d-serine is important in a number of different processes in the CNS, ranging from synaptic plasticity to disease states, including schizophrenia. d-s
Autor:
Steve J, Sullivan, Manuel, Esguerra, Robert J, Wickham, Gabriel E, Romero, Joseph T, Coyle, Robert F, Miller
Publikováno v:
The Journal of physiology. 589(Pt 24)
Glycine and/or D-serine are obligatory coagonists of the N-methyl-D-aspartate receptor (NMDAR). Serine racemase, the D-serine-synthesizing enzyme, is expressed by astrocytes and Müller cells of the retina, but little is known about its role in retin
Autor:
Steve J, Sullivan, Robert F, Miller
Publikováno v:
Journal of neurochemistry. 115(6)
The N-methyl-D-aspartate receptor (NMDAR) co-agonist D-serine is important in a number of different processes in the CNS, ranging from synaptic plasticity to disease states, including schizophrenia. D-serine appears to be the major co-agonist acting