Výsledky vyhledávání - "Steve J. Elliman"

Akademický článek

Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease

Autor: Samantha F. H. de Witte, Ana M. Merino, Marcella Franquesa, Tanja Strini, Johanna A. A. van Zoggel, Sander S. Korevaar, Franka Luk, Madhu Gargesha, Lisa O’Flynn, Debashish Roy, Steve J. Elliman, Philip N. Newsome, Carla C. Baan, Martin J. Hoogduijn

Publikováno v: Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-12 (2017)

Abstract Background Mesenchymal stromal cells (MSC) possess immunomodulatory properties and low immunogenicity, both crucial properties for their development into an effective cellular immunotherapy. They have shown benefit in clinical trials targeti

Externí odkaz: https://doaj.org/article/f6f80968f8ee4d479319109521a6dbe4

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MALDI‐IMS as a Tool to Determine the Myocardial Response to Syndecan‐2‐Selected Mesenchymal Stromal Cell Application in an Experimental Model of Diabetic Cardiomyopathy

Autor: Oliver Klein, Steve J. Elliman, Kathleen Pappritz, Lisa O'Flynn, Timothy O'Brien, Sophie Van Linthout, Fengquan Dong, Nazha Hamdani, Carsten Tschöpe, Árpád Kovács

Purpose: Mesenchymal stromal cells (MSC) are an attractive tool for treatment of diabetic cardiomyopathy. Syndecan-2/CD362 has been identified as a functional marker for MSC isolation. Imaging mass spectrometry (IMS) allows for the characterization o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a7fece137cdc018343457dcba3bdb3
https://refubium.fu-berlin.de/handle/fub188/34368

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Aging of bone marrow- and umbilical cord-derived mesenchymal stromal cells during expansion

Autor: Hannie Douben, Annelies de Klein, Martin J. Hoogduijn, Tanja Strini, Philip N. Newsome, Eleonora E. Lambert, Carla C. Baan, Samantha F.H. de Witte, Steve J. Elliman, Ana Merino, Lisa O'Flynn

Publikováno v: Cytotherapy, 19(7), 798-807. Informa Healthcare
de Witte, S F H, Lambert, E E, Merino, A, Strini, T, Douben, H J C W, O'Flynn, L, Elliman, S J, de Klein, A J E M M, Newsome, P N, Baan, C C & Hoogduijn, M J 2017, ' Aging of bone marrow– and umbilical cord–derived mesenchymal stromal cells during expansion ', Cytotherapy, vol. 19, no. 7, pp. 798-807 . https://doi.org/10.1016/j.jcyt.2017.03.071
Cytotherapy, 19(7), 798-807. Elsevier Inc.

Background aims Mesenchymal stromal cells (MSCs) are used as experimental immunotherapy. Extensive culture expansion is necessary to obtain clinically relevant cell numbers, although the impact on MSCs stability and function is unclear. This study in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c58d456013e0bd2eecb183d5512650c
https://doi.org/10.1016/j.jcyt.2017.03.071

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Epigenetic changes in umbilical cord mesenchymal stromal cells upon stimulation and culture expansion

Autor: Karin Boer, Steve J. Elliman, Ana Merino, Philip N. Newsome, Lisa O'Flynn, Carla C. Baan, Martin J. Hoogduijn, Joyce B. J. van Meurs, Sander S. Korevaar, Samantha F.H. de Witte, Fleur S. Peters

Publikováno v: Cytotherapy, 20(7), 919-929. Informa Healthcare
De Witte, S F H, Peters, F S, Merino, A, Korevaar, S S, Van Meurs, J B J, O'Flynn, L, Elliman, S J, Newsome, P N, Boer, K, Baan, C C & Hoogduijn, M J 2018, ' Epigenetic changes in umbilical cord mesenchymal stromal cells upon stimulation and culture expansion ', Cytotherapy, vol. 20, no. 7, pp. 919-929 . https://doi.org/10.1016/j.jcyt.2018.05.005
Cytotherapy, 20(7), 919-929. Elsevier Inc.

Background Mesenchymal stromal cells (MSCs) are studied for their immunotherapeutic potential. Prior to therapeutic use, MSCs are culture expanded to obtain the required cell numbers and, to improve their efficacy, MSCs may be primed in vitro. Cultur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8dd52bbc04a1de2f01cac60e3475014
https://research.vumc.nl/en/publications/240559cb-2df5-48de-a6f9-0757190c9d09

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Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells

Autor: Philip N. Newsome, Carla C. Baan, Madhu Gargesha, Sander S. Korevaar, Lisa O'Flynn, Anusha S. Shankar, Steve J. Elliman, Jesus M. Sierra Parraga, Michiel G. H. Betjes, Samantha F.H. de Witte, Ana Merino, Martin J. Hoogduijn, Franka Luk, Debashish Roy

Publikováno v: Stem Cells, 36(4), 602-615. Wiley-Blackwell
de Witte, S F H, Luk, F, Sierra Parraga, J M, Gargesha, M, Merino, A, Korevaar, S S, Shankar, A S, O'Flynn, L, Elliman, S J, Roy, D, Betjes, M G H, Newsome, P N, Baan, C C & Hoogduijn, M J 2018, ' Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells ', Stem Cells, vol. 36, no. 4, pp. 602-615 . https://doi.org/10.1002/stem.2779

Mesenchymal stem or stromal cells (MSC) are under investigation as a potential immunotherapy. MSC are usually administered via intravenous infusion, after which they are trapped in the lungs and die and disappear within a day. The fate of MSC after t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d465d2f8e28c5462a83ac18cf5da147
https://pubmed.ncbi.nlm.nih.gov/29341339

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Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease

Autor: Franka Luk, Steve J. Elliman, Martin J. Hoogduijn, Ana Merino, Madhu Gargesha, Debashish Roy, Sander S. Korevaar, Tanja Strini, Philip N. Newsome, Johanna A. A. van Zoggel, Lisa O'Flynn, Carla C. Baan, Samantha F.H. de Witte, Marcella Franquesa

Publikováno v: De Witte, S F H, Merino, A M, Franquesa, M, Strini, T, Van Zoggel, J A A, Korevaar, S S, Luk, F, Gargesha, M, O'Flynn, L, Roy, D, Elliman, S J, Newsome, P N, Baan, C C & Hoogduijn, M J 2017, ' Cytokine treatment optimises the immunotherapeutic effects of umbilical cord-derived MSC for treatment of inflammatory liver disease ', Stem Cell Research and Therapy, vol. 8, no. 1, 140 . https://doi.org/10.1186/s13287-017-0590-6
Stem Cell Research & Therapy
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-12 (2017)
STEM CELL RESEARCH & THERAPY, 8:140. BioMed Central Ltd.
Stem Cell Research and Therapy, 8(1):140. BioMed Central

Background Mesenchymal stromal cells (MSC) possess immunomodulatory properties and low immunogenicity, both crucial properties for their development into an effective cellular immunotherapy. They have shown benefit in clinical trials targeting liver

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66ec2f3d6aff4d6e03dcca6b3466d32
https://research.vumc.nl/en/publications/5b64c345-1a27-46ad-9945-1b6235af6885

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