Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Steve J, Matthews"'
Autor:
Paul Murphy, Yingqi Xu, Sarah L. Rouse, Ellis G. Jaffray, Anna Plechanovová, Steve J. Matthews, J. Carlos Penedo, Ronald T. Hay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
RNF4 is a prototypical single-subunit E3 enzyme that can bind both substrate and ubiquitin-loaded E2. Here, the authors show that the RNF4 N-terminal region, although lacking a defined secondary structure, maintains a compact global conformation to f
Externí odkaz:
https://doaj.org/article/c9de74e062a44078a1b0ae8e8b67bf15
Autor:
Maria Andreasen, Georg Meisl, Jonathan D. Taylor, Thomas C. T. Michaels, Aviad Levin, Daniel E. Otzen, Matthew R. Chapman, Christopher M. Dobson, Steve J. Matthews, Tuomas P. J. Knowles
Publikováno v:
mBio, Vol 10, Iss 1 (2019)
ABSTRACT A wide range of bacterial pathogens have been shown to form biofilms, which significantly increase their resistance to environmental stresses, such as antibiotics, and are thus of central importance in the context of bacterial diseases. One
Externí odkaz:
https://doaj.org/article/ba447dbb4f3b48ca9ad7f0012ba4af9b
Autor:
Gabrielle J. Grundy, Luis M. Polo, Zhihong Zeng, Stuart L. Rulten, Nicolas C. Hoch, Pathompong Paomephan, Yingqi Xu, Steve M. Sweet, Alan W. Thorne, Antony W. Oliver, Steve J. Matthews, Laurence H. Pearl, Keith W. Caldecott
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
Chromosomal single-strand DNA breaks occur frequently and require repair to avoid disease outcomes. Here, the authors show that in bird cells, PARP3 accelerates this repair, and use structural biology and cell biology techniques to reveal details of
Externí odkaz:
https://doaj.org/article/f4adc148d44f418d9df058242e7f3bd6
Autor:
Natalia Pakharukova, James A Garnett, Minna Tuittila, Sari Paavilainen, Mamou Diallo, Yingqi Xu, Steve J Matthews, Anton V Zavialov
Publikováno v:
PLoS Pathogens, Vol 11, Iss 11, p e1005269 (2015)
Gram-negative pathogens express fibrous adhesive organelles that mediate targeting to sites of infection. The major class of these organelles is assembled via the classical, alternative and archaic chaperone-usher pathways. Although non-classical sys
Externí odkaz:
https://doaj.org/article/890e3eec6e5d43c4989447c8f1f34c69
Autor:
Aurélie Mousnier, Gunnar N. Schroeder, Charlotte A. Stoneham, Ernest C. So, James A. Garnett, Lu Yu, Steve J. Matthews, Jyoti S. Choudhary, Elizabeth L. Hartland, Gad Frankel
Publikováno v:
mBio, Vol 5, Iss 4 (2014)
ABSTRACT Legionella pneumophila, the causative agent of Legionnaires’ disease, uses the Dot/Icm type IV secretion system (T4SS) to translocate more than 300 effectors into host cells, where they subvert host cell signaling. The function and host ce
Externí odkaz:
https://doaj.org/article/91b280abc8474731a3f8955074231210
Autor:
Zhihao, Wang, Siyu, Zhao, Yanqing, Li, Kaining, Zhang, Fei, Mo, Jiye, Zhang, Yajing, Hou, Langchong, He, Zhijun, Liu, Yawen, Wang, Yingqi, Xu, Hongliang, Wang, Martin, Buck, Steve J, Matthews, Bing, Liu
Publikováno v:
Journal of molecular biology. 433(3)
Regulation of bacterial stress responding σ
Autor:
Aline, Tabib-Salazar, Nancy, Mulvenna, Konstantin, Severinov, Steve J, Matthews, Sivaramesh, Wigneshweraraj
Publikováno v:
Journal of molecular biology. 431(20)
The parasitic life cycle of viruses involves the obligatory subversion of the host's macromolecular processes for efficient viral progeny production. Viruses that infect bacteria, bacteriophages (phages), are no exception and have evolved sophisticat
Autor:
Aline, Tabib-Salazar, Bing, Liu, Declan, Barker, Lynn, Burchell, Udi, Qimron, Steve J, Matthews, Sivaramesh, Wigneshweraraj
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 115(23)
Viruses that infect bacteria (phages) represent the most abundant living entities on the planet, and many aspects of our fundamental knowledge of phage–bacteria relationships have been derived in the context of exponentially growing bacteria. In th
Autor:
Shih-Ting, Wang, Yiyang, Lin, Nevena, Todorova, Yingqi, Xu, Manuel, Mazo, Subinoy, Rana, Vincent, Leonardo, Nadav, Amdursky, Christopher D, Spicer, Bruce D, Alexander, Alison A, Edwards, Steve J, Matthews, Irene, Yarovsky, Molly M, Stevens
Publikováno v:
Chemistry of Materials
A comprehensive understanding of the mechanisms of interaction between proteins or peptides and nanomaterials is crucial for the development of nanomaterial-based diagnostics and therapeutics. In this work, we systematically explored the interactions
Autor:
Alan Roberts, Richard I. Corfield, Steve J. Matthews, Evan-Kåre Hansen, Nick Kusznir, Robert J. Hooper
Publikováno v:
Petroleum Geoscience. 15:27-43
The post-Jurassic bathymetric and subsidence history of the Mid-Norwegian Atlantic margin (More and Voring basins) has been investigated using the technique of 3D-flexural backstripping. Eleven mapped horizons from seabed to the Base Cretaceous have