Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Steve Horner"'
Publikováno v:
Regulatory Toxicology and Pharmacology. 65:334-343
An analysis of target organ toxicities in first time in man (FTiM) toxicity studies for 77 AstraZeneca candidate drugs (CDs) was conducted across a range of therapy areas. In the rodent, the most frequently affected organ was the liver followed by ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc8e16339f4b1b6624b204136b310e3
https://doi.org/10.1016/j.yrtph.2013.02.002
https://doi.org/10.1016/j.yrtph.2013.02.002
Autor:
Steve Horner, James G. Eberhart
Publikováno v:
Journal of Chemical Education. 87:608-612
A simple technique appropriate for introductory materials science courses is outlined for the calculation of bond energies in metals from lattice energies. The approach is applied to body-centered cubic (bcc), face-centered cubic (fcc), and hexagonal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f684a3e5823e5390db5912eb98cbcb0b
https://doi.org/10.1021/ed100189v
https://doi.org/10.1021/ed100189v
Autor:
Duncan Armstrong, Peter Cotton, Helen Prior, Chris Lawrence, Graham Betton, Ruth A. Roberts, Paul A. Duffy, Steve Horner, Karen Philp, Nick McMahon, Judith Horner
Publikováno v:
European Journal of Cancer Supplements. 5:143-151
Cancer chemotherapeutic drugs, by their very nature of targeting robust and often rapidly dividing cells, inherently carry more toxicological burden and risk than drugs aimed at treating more benign disease. However, clinical oncologists have a conti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f944d819f107dfcce4ff874fae92c8c
https://doi.org/10.1016/s1359-6349(07)70034-4
https://doi.org/10.1016/s1359-6349(07)70034-4
Autor:
Salvatore L. Battaglia, April W. Simon, Lynn G. Tarkington, Phillip P Brown, Michael J. Mack, Steve Horner, Steven D. Culler, Edmund R. Becker
Publikováno v:
The Annals of Thoracic Surgery. 74:2113-2119
Background It has been well documented that women have higher morbidity and mortality rates than men following coronary artery bypass graft (CABG) surgery. In view of this evidence, we investigated the following question: compared with on-pump CABG s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::095a6d7b93ded6e6f39b70852a1961b4
https://doi.org/10.1016/s0003-4975(02)03988-7
https://doi.org/10.1016/s0003-4975(02)03988-7
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 70(1)
We have previously reported the profile of toxic effects with respect to target organs (defined as organs showing histopathological changes) observed in rodent and non-rodent toxicity studies conducted prior to first time in man (FTIM) for 77 AstraZe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892f2768192cdbc512fc8adf99050ab4
https://pubmed.ncbi.nlm.nih.gov/25020275
https://pubmed.ncbi.nlm.nih.gov/25020275
Publikováno v:
Toxicology Letters. 229:S237-S238
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76ee5009dfbc996942ab6fee855106d1
https://doi.org/10.1016/j.toxlet.2014.06.794
https://doi.org/10.1016/j.toxlet.2014.06.794
Autor:
Steve Horner, William Burton Elliot, Alexander Randall Sandoval, Stephen Thomas Grayson, Patricio Alban
Publikováno v:
All Days.
This paper gives the details and results of a successful workover program conducted offshore California in 2006. The wells are highly deviated, producing oil, gas, and water from natural fractures. Analysis from a new production-logging tool, coupled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5b50b5a86bbf2220d91bd5de8032be2
https://doi.org/10.2118/110693-ms
https://doi.org/10.2118/110693-ms
Autor:
Iraj Ershaghi, Steve Horner
Venoco Inc, intends to re-develop the Monterey Formation, a Class III basin reservoir, at South Ellwood Field, Offshore Santa Barbara, California. Well productivity in this field varies significantly. Cumulative Monterey production for individual wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7c1ebe9f0e7303bcb8b371932ba2fb
https://doi.org/10.2172/820687
https://doi.org/10.2172/820687
Publikováno v:
All Days.
The Monterey Formation in the oilfields of California Offshore represents a unique flow system where the major fractures and faults serve as conduits and a system of microfractures supports these major channels. A rendering of the seismic and sub-sei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9ccfe6f93dfc354da2d98c0bb70a1c9
https://doi.org/10.2118/77739-ms
https://doi.org/10.2118/77739-ms
Publikováno v:
All Days.
Accurate production profiling in the fractured Monterey wells of offshore California is a challenging endeavor. Deviated wells, three-phase flow, and the unpredictable nature of production from natural fractures, makes possible almost any type of flo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e210a03e8a81b7c580eb0c6016ad600
https://doi.org/10.2118/76749-ms
https://doi.org/10.2118/76749-ms