Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Steve Hibbert"'
Autor:
Grace Auld, Christine Girges, Huw R. Morris, Vincenzo Libri, John Dickson, Monty Silverdale, Alison J. Yarnall, Patricia Limousin, Simon S. Skene, Silvia Del Din, Lynn Rochester, Kashfia Chowdhury, Steve Hibbert, Michele T.M. Hu, Gordon W Duncan, Dilan Athauda, Alexa King, Christine Lo, Camille Carroll, Marisa Chau, Thomas Foltynie, Ray Chaudhuri, Kate Maclagan, Rachel J. Gibson, Nirosen Vijiaratnam, Rachael Hunter
Publikováno v:
BMJ Open
IntroductionParkinson’s disease (PD) is a common neurodegenerative disorder with substantial morbidity. No disease-modifying treatments currently exist. The glucagon like peptide-1 receptor agonist exenatide has been associated in single-centre stu
Autor:
Luca Zampedri, Kate Maclagan, Thomas Foltynie, Kashfia Chowdhury, Iciar Aviles-Olmos, Simon S. Skene, Dilan Athauda, Patricia Limousin, Natalia Budnik, Steve Hibbert
Publikováno v:
Journal of Parkinson's Disease. 8:247-258
Background Exenatide is a GLP-1 receptor agonist that was recently studied for potential disease-modifying effects in a randomised, placebo-controlled clinical trial in patients with moderate stage Parkinson’s disease, and showed positive effects o
Autor:
Nigel H. Greig, Dawn Letchford, Martha Bajwa-Joseph, Dilan Athauda, Simon S. Skene, Natalia Budnik, Iciar Aviles-Olmos, Luca Zampedri, Andrew J. Lees, Patricia Limousin, Yazhou Li, Thomas Foltynie, Kashfia Chowdhury, Kate Maclagan, Susan Tebbs, John Dickson, Thomas T. Warner, Steve Hibbert
Publikováno v:
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Summary Background Exenatide, a glucagon-like peptide-1 (GLP-1) receptor agonist, has neuroprotective effects in preclinical models of Parkinson's disease. We investigated whether these effects would be apparent in a clinical trial. Methods In this s
Autor:
Alastair Windsor, Sara McCartney, Jonny Vlahos, Charles Murray, Caron Innes, Farooq Rahman, Jade Dyer, Mairead Tennent, Richard Pollok, Richard Beable, Roman Jastrub, Deborah Scrimshaw, Antony Higginson, Anisur Rahman, Anne Miles, Steve Morris, C Alexakis, Fergus Thursby-Pelham, Andrew Plumb, Hannah Lambie, Nicola Gibbons, Sue Tebbs, Peter Wylie, Anthony O'Connor, Pranitha Veeramalla, Arun Gupta, Adriana Martinez, A Slater, Steve Hibbert, Stuart Bloom, Roser Vega, Laura L. Quinn, Phillip Lung, Rajapandian Ilangovan, Ilan Jacobs, R Greenhalgh, Roger Lapham, Francois Porte, Anita Wale, Rachel Baldwin-Cleland, Niall Power, Doris Quartey, Manuel Rodriguez-Justo, Zainib Shabir, Harbir S. Sidhu, Simon Travis, Damian Tolan, Ian Zealley, Shonit Punwani, Hameed Rafiee, Stuart A. Taylor, Craig Mowat, Ailsa Hart, Mani Naghibi, Evgenia Mainta, Simona de Caro, PJ Hamlin, James Pilcher, Steve Halligan, Simona Fourie, Joey Clemente, Susan Mallett, Claire Ward, Wivijin Piga, Nigel Scott, Uday Patel, Helen Bungay, Shameer Mehta, Teresita Beeston, Maggie Betts, Richard Ellis, Gillian Duncan, Rachel Hyland, Morgan Moorghen, Gauraang Bhatnagar, Ian Johnston
Publikováno v:
The Lancet. Gastroenterology & Hepatology
Magnetic resonance enterography (MRE) and ultrasound are used to image Crohn's disease, but their comparative accuracy for assessing disease extent and activity is not known with certainty. Therefore, we did a multicentre trial to address this issue.
Autor:
Patricia Limousin, Steve Hibbert, Simon S. Skene, Dilan Athauda, Luca Zampedri, Kate Maclagan, Natalia Budnik, Thomas Foltynie, Iciar Aviles-Olmos, Kashfia Chowdhury
Publikováno v:
The European journal of neuroscience. 49(3)
Exenatide, a glucagon-like peptide-1 agonist and a licensed treatment for Type 2 diabetes significantly reduced deterioration in motor symptoms in patients with Parkinson’s disease in a randomized, placebo-controlled trial. In addition, there were
Autor:
Paul J. Sheridan, Alan Bernjak, Scott E. Williams, Robert A. Fawdry, Jenny Freeman, Elaine Chow, Simon Heller, Steve Hibbert
Publikováno v:
Diabetes
Recent trials of intensive glycemic control suggest a possible link between hypoglycemia and excess cardiovascular mortality in patients with type 2 diabetes. Hypoglycemia might cause arrhythmias through effects on cardiac repolarization and changes
Publikováno v:
Applied Surface Science. 172:135-143
The cleanability of stainless steel using a starch soil was investigated using X-ray photoelectron spectroscopy and atomic force microscopy. Two cleaning regimes were examined: high pressure spray system removed absorbed material much more effectivel
Autor:
J. C. Edwards, Anneli C. Brisley, Per Krüger, Rudolf Knes, Steve Hibbert, Caroline S. Nunnerley, J. M. Davies, Alan J. Paul, Robert F. Sunderland
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 174:287-295
The use of plasma treatment for the modification of polystyrene microtiter wells has been evaluated by contact angle measurements, X-ray photoelectron spectroscopy (XPS), and time-of-flight secondary ion mass spectrometry (ToF-SIMS). The contact angl
Autor:
Paul Roberts, Simon Cotterill, Mike Griffiths, Denise Tritton, Anna Kelsey, Chris Mitchell, Steve Hibbert, Helen Middleton, Nick Bown, Simon Larkins
Publikováno v:
Medical and pediatric oncology. 38(1)
Background Tumor genetic features reported to correlate with adverse outcome in Wilms tumor include karyotype complexity, losses of material from the short arm of chromosome 1 and from the long arms of chromosomes 11, 16 and 22 and gain of material f
Autor:
Steve Hibbert
Publikováno v:
New Scientist. 213:29