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Autor:
Laura J. Bloem, Philip W. Iversen, Kenneth E. Gould, John N. Lorenz, Xiaohong Yu, Vivek J. Kadambi, Najia Jin, Steve H. Zuckerman, Xushan Wang, Michael E. Christe
Publikováno v:
Journal of molecular and cellular cardiology. 37(3)
Mixed lineage kinase 7 (MLK7) is a recently identified mitogen-activated protein kinase kinase kinase with enriched expression in skeletal muscle and heart. When over-expressed in cardiac myocytes, MLK7 activates both the p38 and c-Jun N-terminal kin