Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Steve Fogal"'
Autor:
Emma K. Haley, Diane Mierz, Mark Panzenbeck, Steve Fogal, M. Lamine Mbow, Mederbek Matmusaev, Susan Lukas, Svenja Mayer-Wrangowski, Miller Craig Andrew, Jie Zheng, F. James King, Clemens Braun, Fergus R. Byrne, Joerg Ermann, Donna Terenzio, Li Li, Felix Jost, Jay S. Fine, Lori Patnaude, Naitee Ting, Alex P. Klimowicz, Jane Chime, Tom Simpson, Peng Hsiao, David Csordas
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 321(5)
Mouse and human data implicate the NOD1 and NOD2 sensors of the intestinal microbiome and the associated signal transduction via the receptor interacting protein kinase 2 (RIPK2) as a potential key signaling node for the development of inflammatory b
Autor:
Michael Dziegelewski, David Presky, Susan van Tongeren, Steve Fogal, Rachel Kroe-Barrett, Helen Wu, Sanjaya Singh, Tobias Litzenberger, Scott Brodeur, Gale Hansen, Christine Grimaldi, Eliud Sepuldeva, Zhong-Fu Huang, Dongmei Liu, Hua Li, Kerry-Leigh Ralph, Lee Frego, Jennifer Ahlberg
Publikováno v:
International Journal of Pharmaceutics. 609:121162
Antibodies targeting the CD40-CD40L pathway have great potential for treating autoimmune diseases like rheumatoid arthritis, systemic lupus erythematosus (SLE), lupus nephritis (LN), and inflammatory bowel diseases (IBD). However, in addition to the
Autor:
Donna Terenzio, Fergus R. Byrne, Susan Lukas, Emma K. Haley, Joerg Ermann, Jie Zheng, Felix Jost, Frank Li, Naitee Ting, Mark Panzenbeck, Frank J. King, David Csordas, Miller Craig Andrew, Svenja Mayer-Wrangowski, Jane Chime, Steve Fogal, Clemens Braun, Mederbek Matmusaev, Jay S. Fine, Diane Mierz, Alexander C. Klimowicz
Publikováno v:
Gastroenterology. 160:S-326
Autor:
Louise K. Modis, Yong Wang, Stephanie M. Ng, Sulagna Sanyal, Brian Nicholas Cook, Lemieux Rene M, Melissa Hill-Drzewi, Younggi Choi, Wei Xu, Kristina Gueneva-Boucheva, Diva Sze-Ming Chan, Lori Patnaude, Edward Pack, Eugene R. Hickey, Michael B. Fisher, Can Mao, Horan Joshua Courtney, Lynne Canne Bannen, Steve Fogal, Morrison B. Mac, Shawn Anderson
Publikováno v:
Bioorganicmedicinal chemistry letters. 24(20)
The discovery of a new series of selective S1P1 agonists is described. This series of piperazinyl-oxadiazole derivatives was rapidly optimized starting from high-throughput screening hit 1 to afford potent and selective lead compound 10d. Further SAR