Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Steve Finegan"'
Autor:
Steve Finegan, Jennifer L. Liras, John Schafer, Gregory G. Stone, Sarah K. Wade, Ann G. Connolly, Rhonda Monahan, Katherine E. Brighty, Joan Duignan, Steven J. Brickner, Phuong Le, Ivan J. Samardjiev, Richard P. Zaniewski, Dennis Girard, Jon Bordner, Meghan Maloney
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:276-279
SAR studies and optimization of various modified Hygromycin A fluoroalkyl ethers, which led to the discovery of the highly potent 4'-(2-cyclopropyl-2-fluoroethyl ether) antibacterial CE-156811 (1) derived from truncation of the ribose ring and difluo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d31058e211b4e5cd78b92b592ecef72f
https://doi.org/10.1016/j.bmcl.2010.11.022
https://doi.org/10.1016/j.bmcl.2010.11.022
Autor:
Meghan Maloney, Steve Finegan, Dennis Girard, Gregory G. Stone, John Schafer, Sarah K. Wade, Phuong Le, Steven J. Brickner, Michael D. Huband, Joan Duignan, Richard P. Zaniewski
Publikováno v:
Antimicrobial agents and chemotherapy. 52(7)
We evaluated a novel truncated hygromycin A analog in which the furanose ring was replaced with a 2-fluoro-2-cyclopropylethyl substituent for its activity against multidrug resistant gram-positive bacteria and compared its activity to the activities
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54257226f2409edddbf8487000e85f25
https://pubmed.ncbi.nlm.nih.gov/18426902
https://pubmed.ncbi.nlm.nih.gov/18426902