Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Steve F. Abcouwer"'
Publikováno v:
BioTechniques, Vol 24, Iss 5, Pp 803-808 (1998)
14CO2 capture is commonly used to evaluate the cellular oxidation rate of respiratory substrates. A modification of the established 14CO2-capture method was developed that enables the use of cells in adherent culture and easy analysis of multiple sam
Externí odkaz:
https://doaj.org/article/1d8deffcb6d64fe39e11b707db40b923
Publikováno v:
BioTechniques, Vol 24, Iss 2, Pp 216-218 (1998)
Externí odkaz:
https://doaj.org/article/71fdca6ef4a645f1894faccffdb3b4bb
Control of protein synthesis in insulin-responsive tissues has been well characterized, but relatively little is known about how this process is regulated in nervous tissues. The retina exhibits a relatively high protein synthesis rate, coinciding wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3162fd12eb530479a271fee0c6da97ea
https://europepmc.org/articles/PMC4572451/
https://europepmc.org/articles/PMC4572451/
Autor:
Lorraine M. Deck, Waylon M. Weber, Steve F. Abcouwer, David L. Vander Jagt, Robert E. Royer, Ekaterina V. Bobrovnikova-Marjon, C. Nathaniel Roybal, Lucy A. Hunsaker
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:2450-2461
The transcription factor NFkappaB (NFkappaB) is up-regulated in many cancer cells where it contributes to development of the pro-survival, anti-apoptotic state. The natural product curcumin is a known inhibitor of activation of NFkappaB. Enone analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d543b1257b4ec66537ecbb19598525
https://doi.org/10.1016/j.bmc.2005.11.035
https://doi.org/10.1016/j.bmc.2005.11.035
Publikováno v:
Bioorganic & Medicinal Chemistry. 13:3811-3820
The natural product curcumin (diferuloylmethane, 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione), obtained from the spice turmeric, exhibits numerous biological activities including anti-cancer, anti-inflammatory, and anti-angiogenesis a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fbf111eb5eaec8cdf15615eb4c20eb
https://doi.org/10.1016/j.bmc.2005.03.035
https://doi.org/10.1016/j.bmc.2005.03.035
Autor:
C. Nathaniel Roybal, Olena Barbash, Steve F. Abcouwer, Lucy A. Hunsaker, David L. Vander Jagt
Publikováno v:
Journal of Biological Chemistry. 280:20331-20339
Aberrant retinal expression of vascular endothelial growth factor (VEGF) leading to neovascularization is a central feature of age-related macular degeneration and diabetic retinopathy, two leading causes of vision loss. Oxidative stress is suggested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4ddddb561e0bc7b9b0687a0f7ed2f12
https://doi.org/10.1074/jbc.m411275200
https://doi.org/10.1074/jbc.m411275200
Autor:
Philip L. Marjon, Ekaterina V. Bobrovnikova-Marjon, Olena Barbash, David L. Vander Jagt, Steve F. Abcouwer
Publikováno v:
Cancer Research. 64:4858-4869
Vascular endothelial growth factor (VEGF) and interleukin-8/CXCL8 (IL-8) are prominent pro-angiogenic and pro-metastatic proteins that represent negative prognostic factors in many types of cancer. Hypoxia is thought to be the primary environmental c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fab567adef7f5ce2dd6e69f1f99c2cf
https://doi.org/10.1158/0008-5472.can-04-0682
https://doi.org/10.1158/0008-5472.can-04-0682
Publikováno v:
The Journal of Nutrition. 131:2467S-2474S
Whether on the scale of a single cell, organ or organism, glutamine homeostasis is to a large extent determined by the activities of glutaminase (GA, EC 3.5.1.2) and glutamine synthetase (GS, EC 6.3.1.2), the two enzymes that are the focus of this re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5370cc1d600eeb476bd64c4e501e4a83
https://doi.org/10.1093/jn/131.9.2467s
https://doi.org/10.1093/jn/131.9.2467s
Publikováno v:
Journal of Biological Chemistry. 274:28645-28651
The expression of the growth arrest- and DNA damage-inducible genes, GADD45 and GADD153/CHOP (C/EBP-homologous protein), as well as GRP78 (glucose-regulated protein of 78 kDa) was examined in several human breast cell lines subjected to acute glutami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c98a8aa8baa103fb88a6629ae2888f2a
https://doi.org/10.1074/jbc.274.40.28645
https://doi.org/10.1074/jbc.274.40.28645
Publikováno v:
Nutrition. 15:687-696
Chemotherapy causes severe host immune depression and consequently increases susceptibility to infection. Dietary glutamate (GLU) serves as a stable substrate for the formation of glutamine (GLN), which is an important fuel and metabolic precursor fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ffc97968bc314a0c5069b2b48e70b0
https://doi.org/10.1016/s0899-9007(99)00153-7
https://doi.org/10.1016/s0899-9007(99)00153-7