Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Steve F Bronk"'
Autor:
Satoshi Kurita, Justin L Mott, Sophie C Cazanave, Christian D Fingas, Maria E Guicciardi, Steve F Bronk, Lewis R Roberts, Martin E Fernandez-Zapico, Gregory J Gores
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18330 (2011)
TRAIL is a promising therapeutic agent for human malignancies. TRAIL often requires mitochondrial dysfunction, referred to as the Type II death receptor pathway, to promote cytotoxicity. However, numerous malignant cells are TRAIL resistant due to in
Externí odkaz:
https://doaj.org/article/6eea11e93bee4a96bbdff2b0f692bbfb
Autor:
Gregory J. Gores, Alphonse E. Sirica, Frank A. Sinicrope, Steve F. Bronk, Nathan W. Werneburg, Boris R.A. Blechacz, Rory L. Smoot
Supplementary Figure 2 from A Bax-Mediated Mechanism for Obatoclax-Induced Apoptosis of Cholangiocarcinoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a180b460bf1ffd34966148f2a0fa22a
https://doi.org/10.1158/0008-5472.22384004.v1
https://doi.org/10.1158/0008-5472.22384004.v1
Autor:
Gregory J. Gores, Alphonse E. Sirica, Frank A. Sinicrope, Steve F. Bronk, Nathan W. Werneburg, Boris R.A. Blechacz, Rory L. Smoot
Supplementary Figure Legends 1-2 from A Bax-Mediated Mechanism for Obatoclax-Induced Apoptosis of Cholangiocarcinoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fbdf8636e047692d9111ff2ab6bf4ac
https://doi.org/10.1158/0008-5472.22384001.v1
https://doi.org/10.1158/0008-5472.22384001.v1
Autor:
Gregory J. Gores, Alphonse E. Sirica, Frank A. Sinicrope, Steve F. Bronk, Nathan W. Werneburg, Boris R.A. Blechacz, Rory L. Smoot
Supplementary Figure 1 from A Bax-Mediated Mechanism for Obatoclax-Induced Apoptosis of Cholangiocarcinoma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597e739746cb54855f8b41941562a7e8
https://doi.org/10.1158/0008-5472.22384007
https://doi.org/10.1158/0008-5472.22384007
Autor:
Lorena Loarca, Lorena Marcano Bonilla, Nicholas F. LaRusso, Maria J. Lorenzo Pisarello, Eugene W. Krueger, Gregory J. Gores, Guang Shi, Anuradha Krishnan, Christy E. Trussoni, Bing Huang, Leslie Morton, Robert C. Huebert, Steve F. Bronk, Patrick L. Splinter, Thiago M. De Assuncao, Nidhi Jalan-Sakrikar, Steve P. O'Hara
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Primary sclerosing cholangitis (PSC) is an incurable, fibroinflammatory biliary disease for which there is no effective pharmacotherapy. We recently reported cholangiocyte senescence as an important phenotype in PSC while others showed that portal ma
Autor:
Bart van de Sluis, Grace G. Nelson, Sameh A. Youssef, Erin Hurley, Raul O. Fierro Velasco, Ines Sturmlechner, Alain de Bruin, Jazeel F. Limzerwala, Janine H. van Ree, Gregory J. Gores, Daniel R. O'Brien, Erik Jan van Deursen, Lewis R. Roberts, Floris Foijer, Hilda van den Bos, Jean Pierre A. Kocher, Steve F. Bronk, Cheng Zhang, Khaled Aziz, Hu Li, Diana C.J. Spierings, Karthik B. Jeganathan, Jan M. van Deursen
Publikováno v:
Gastroenterology, 157(1). W B SAUNDERS CO-ELSEVIER INC
Gastroenterology, 157(1), 210. W.B. Saunders Ltd
Gastroenterology
Gastroenterology, 157(1), 210. W.B. Saunders Ltd
Gastroenterology
BACKGROUND & AIMS: The CCNE1 locus, which encodes cyclin E1, is amplified in many types of cancer cells and is activated in hepatocellular carcinomas (HCCs) from patients infected with hepatitis B virus or adeno-associated virus type 2, due to integr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::770ac0061154c8a71213667f3c9d4d1a
https://research.rug.nl/en/publications/4be5d7e1-cfb8-4caa-a000-06d093199aad
https://research.rug.nl/en/publications/4be5d7e1-cfb8-4caa-a000-06d093199aad
Publikováno v:
Gastroenterology. 156:S-188
Publikováno v:
Gastroenterology. 156:S-1198
Autor:
Gregory J. Gores, Yunhao Zhao, Michael Pollak, Chadi Zakaria, Masahiro Morita, Mamatha Bhat, Tommy Alain, Nahum Sonenberg, Nataliya Razumilava, Maritza Jaramillo, Domenick Zammit, Tyson E. Graber, Akiko Yanagiya, Peter Metrakos, Steve F. Bronk
Publikováno v:
Oncotarget
Oncotarget, Impact journals, 2016, ⟨10.18632/oncotarget.10671⟩
Oncotarget, Impact journals, 2016, ⟨10.18632/oncotarget.10671⟩
International audience; Metformin inhibits the mammalian target of rapamycin complex 1 (mTORC1) signaling pathway, which is frequently upregulated in hepatocellular carcinoma (HCC). Metformin has also been shown to induce apoptosis in this cancer. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd2756a94873df596b2fc658dd8f4dd2
https://hal-pasteur.archives-ouvertes.fr/pasteur-01350841/file/10671-162277-2-PB.pdf
https://hal-pasteur.archives-ouvertes.fr/pasteur-01350841/file/10671-162277-2-PB.pdf
Autor:
Steve F. Bronk, Gregory J. Gores, Gary Thomas, Laurel Thomas, Nathan W. Werneburg, Maria Eugenia Guicciardi, Jimmy D. Dikeakos
Publikováno v:
Journal of Biological Chemistry. 287:24427-24437
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis of liver cancer cell lines requires death receptor-5 (DR5)-dependent permeabilization of lysosomal membranes. Ligated DR5 triggers recruitment of the proapoptotic prote