Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Steve Dunham"'
Autor:
Mark C. Sulavik, Debra Hanna, Bill Dunkle, Li Ann Wang, V. Hayden Thomas, Laura A. Skerlos, Tong Zhu, Chris Limberakis, Zhigang Wang, Amy Whitton, Michael Kuhn, C. Kendall Stover, Jeff Ohren, John A. Shelly, J.V.N. Vara Prasad, Steve Dunham, H. James Harwood, Michael D. Huband, J. Richard Miller, Shawn Mehrens, Alla Karnovsky, Susan Buist, W. Thomas Mueller, Jia Y. Liu, Steve Vanderroest, Craig Banotai, Adam Ogden, Lakshmi Narasimhan, Matthew Bowman, Igor Mochalkin
Publikováno v:
Proceedings of the National Academy of Sciences. 106:1737-1742
As the need for novel antibiotic classes to combat bacterial drug resistance increases, the paucity of leads resulting from target-based antibacterial screening of pharmaceutical compound libraries is of major concern. One explanation for this lack o
Publikováno v:
Analytical Biochemistry. 385:321-325
Bacterial resistance to antibiotic therapy remains a worldwide problem. In Pseudomonasaeruginosa, rates of efflux confer inherent resistance to many antimicrobial agents, including fluoroquinolones, due to a high level of expression and a relatively
Autor:
Steve Dunham
Excel at editing!The editor's job encompasses much more than correcting commas and catching typos. Your chief mission is to help writers communicate effectively--which is no small feat. Whether you edit books, magazines, newspapers, or online publica
Autor:
Christie G. Brouillette, Steve Dunham, Karen Siegel, Mark E. Snow, Irina I. Protasevich, J. Ronald Rubin, Rocco Gogliotti
Publikováno v:
Biochemistry. 43:13380-13389
The antibacterial target enoyl-acyl carrier protein (ACP) reductase is a homotetrameric enzyme that catalyzes the last reductive step of fatty acid biosynthesis. In the present paper, four 2-(2-hydroxyphenoxy)phenol inhibitors, wherein the 4-position
Autor:
Janet M. Daly, Steve Dunham
Publikováno v:
Veterinary Record. 179:51-51
CANINE parvovirus remains a significant disease of domestic dogs despite the availability of safe and effective vaccines. Canine parvovirus (CPV-2) first emerged in the 1970s as a result of interspecies transmission. The original CPV-2 strain was rap
Autor:
Rajeshwar Singh, E. Themis Joannides, Brian M. Watson, H. D. Hollis Showalter, Steve Dunham, Tuan P. Tran, Dai Q. Nguyen, Michael D. Huband, Michael Stier, Stephen J. Gracheck, Jia Yeu Liu, John M. Domagala, Joseph P. Sanchez, Joel C. Bronstein, Debra Hanna, Jeffrey W. Gage, Martin A. Shapiro, Edmund L. Ellsworth
Publikováno v:
Journal of medicinal chemistry. 49(22)
The 3-aminoquinzolinediones represent a new series of antibacterial agents structurally related to the fluoroquinolones. They are inhibitors of bacterial gyrase and topoisomerase IV and demonstrate clinically useful antibacterial activity against fas