Výsledky vyhledávání - "Steve D. Levin"

Abstract 4550: CD80 vIgD-Fc proteins combine checkpoint antagonism and costimulatory signaling for potent antitumor immunity

Autor: Stacey R. Dillon, Ryan Swanson, Steve D. Levin, Martin F. Wolfson, Mark F. Maurer, Chelsea J. Gudgeon, Chris L. Navas, Joseph L. Kuijper, Katherine E. Lewis, Michael Kornacker

Publikováno v: Cancer Research. 78:4550-4550

Introduction: PD-1 pathway antagonists have revealed the importance of checkpoint pathways in regulating antitumor immunity, but an existing immune response is generally required for clinical efficacy. Specific T cell costimulation through CD28 is ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b8eea358913e2c204111044461c5dd5
https://doi.org/10.1158/1538-7445.am2018-4550

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Analysis of the role of MKK-4/Sek-1 in T cell development and apoptosis

Autor: Leonard I. Zon, Katherine A. Forbush, Jose Alberola-Ila, Steve D. Levin, Roger M. Perlmutter, Greg Barton

Publikováno v: International Immunology. 10:1077-1082

The stress-activated protein kinases (SAPK) are a group of dual-specificity kinases with potential roles in the control of apoptosis and proliferation. In most cells they are regulated through phosphorylation by MKK-4. We have investigated the role o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01e54e7572ca3f371796999101e4395
https://doi.org/10.1093/intimm/10.8.1077

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