Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Steve Cleverley"'
Publikováno v:
The Journal of Experimental Medicine
During the early stages of thymopoiesis, cell survival is controlled by cytokines that regulate the expression of antiapoptotic proteins such as Bcl-2. At the pre-T cell stage, a critical checkpoint for β chain selection is monitored by the tumor su
Publikováno v:
Nature Methods. 2:393-395
Surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS) represents the successful combination of retentate chromatography and mass spectrometry, and this technology is an integral part of Ciphergen's ProteinChip S
Publikováno v:
The EMBO Journal. 15:3923-3933
The transcription factor, Nuclear Factor of Activated T cells (NFAT) is a major target for p21ras and calcium signalling pathways in the IL-2 gene and is induced by p21ras signals acting in synergy with calcium/calcineurin signals. One p21ras effecto
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 878(2)
Immunoaffinity approaches remain invaluable tools for characterization and quantitation of biopolymers. Their application in separation science is often limited due to the challenges of immunoassay development. Typical end-point immunoassays require
Autor:
Laila Samady, Robert S. Coffin, C. E. Lilley, Yvonne McGrath, Steve Cleverley, Emanuela Costigliola, Jill Smith, David S. Latchman, Luci P. MacCormac, Benny Chain
Publikováno v:
Journal of virology. 77(6)
Herpes simplex virus (HSV) infects dendritic cells (DC) efficiently but with minimal replication. HSV, therefore, appears to have evolved the ability to enter DC even though they are nonpermissive for virus growth. This provides a potential utility f
Publikováno v:
Oncogene. 19(1)
In vitro studies in model cell lines have implicated the GTPase Rho in the control of diverse cellular responses including the control of the actin cytoskeleton and the regulation of cell cycle progression. It is also reported that the transformation
Autor:
Steve Cleverley, Stefan Henning
Publikováno v:
Immunologic research. 20(1)
Almost a decade ago, the small GTPase Ras was shown to be activated in response to antigen receptor triggering in T cells. Since then, Ras has been further characterized as a central molecule for the regulation of signal transduction pathways in lymp
Publikováno v:
Current Biology. 9(12):657-S1
Development of thymocytes can be staged according to the levels of expression of the cell-surface markers CD4, CD8, CD44, CD25 and CD2. Thymocyte development is regulated by a complex signalling network [1], one component of which is the GTPase Rho.
Publikováno v:
Publishers Weekly. 2/25/2013, Vol. 260 Issue 8, p27-137. 94p. 40 Color Photographs.
Publikováno v:
Optician; 3/22/2013 Supplement, p12-74, 44p