Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Steve C. Almo"'
Autor:
Joshua E. Drumm, Kaixia Mi, Patrick Bilder, Meihao Sun, Jihyeon Lim, Helle Bielefeldt-Ohmann, Randall Basaraba, Melvin So, Guofeng Zhu, JoAnn M. Tufariello, Angelo A. Izzo, Ian M. Orme, Steve C. Almo, Thomas S. Leyh, John Chan
Publikováno v:
PLoS Pathogens, Vol 5, Iss 9 (2009)
Externí odkaz:
https://doaj.org/article/c0fc356f1d6e4b838d49ad94795b1744
Autor:
Lisa N Glass, Ganduri Swapna, Sivagami Sundaram Chavadi, JoAnn M Tufariello, Kaixia Mi, Joshua E Drumm, TuKiet T Lam, Guofeng Zhu, Chenyang Zhan, Catherine Vilchéze, Jesus Arcos, Yong Chen, Lijun Bi, Simren Mehta, Steven A Porcelli, Steve C Almo, Syun-Ru Yeh, William R Jacobs, Jordi B Torrelles, John Chan
Publikováno v:
PLoS Pathogens, Vol 13, Iss 7, p e1006515 (2017)
We have previously shown that the Mycobacterium tuberculosis universal stress protein Rv2623 regulates mycobacterial growth and may be required for the establishment of tuberculous persistence. Here, yeast two-hybrid and affinity chromatography exper
Externí odkaz:
https://doaj.org/article/6d48c6ed73d94b888c9e8814f3059ad9
Native mass spectrometry detection of ligand-protein complexes allowed rapid detection of natural product binders of apo and calcium-bound S100A4 (a member of the metal binding protein S100 family), T cell/transmembrane, immunoglobulin (Ig), and muci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f98c2e959a4d91b6105ac71b3f1b569
https://europepmc.org/articles/PMC6195442/
https://europepmc.org/articles/PMC6195442/
Autor:
Guofeng Zhu, Jordi B. Torrelles, Catherine Vilchèze, Sivagami Sundaram Chavadi, Simren Mehta, Lijun Bi, Ganduri Swapna, William R. Jacobs, Steven A. Porcelli, Kaixia Mi, TuKiet T. Lam, Syun-Ru Yeh, JoAnn M. Tufariello, Chenyang Zhan, John Chan, Jesus Arcos, Steve C. Almo, Lisa N. Glass, Joshua E. Drumm, Yong Chen
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 13, Iss 7, p e1006515 (2017)
PLoS Pathogens, Vol 13, Iss 7, p e1006515 (2017)
We have previously shown that the Mycobacterium tuberculosis universal stress protein Rv2623 regulates mycobacterial growth and may be required for the establishment of tuberculous persistence. Here, yeast two-hybrid and affinity chromatography exper
Publikováno v:
Journal of Molecular Biology. 426:945-961
Secreted and cell-surface-localized members of the immunoglobulin superfamily (IgSF) play central roles in regulating adaptive and innate immune responses and are prime targets for the development of protein-based therapeutics. An essential activity
Autor:
Dmitry A. Rodionov, Matthew W. Vetting, Andrei L. Osterman, Irina A. Rodionova, Steve C. Almo, Xiaoqing Li
Publikováno v:
The FASEB Journal. 30
Autor:
Keith Clinch, Vern L. Schramm, Douglas R. Crump, Meng-Chiao Ho, Emilio F. Merino, Peter C. Tyler, Keith Z. Hazleton, Maria B. Cassera, Steve C. Almo, Irving Rosario
Publikováno v:
Chemistry & Biology. 19(6):721-730
Summary Plasmodium falciparum , the primary cause of deaths from malaria, is a purine auxotroph and relies on hypoxanthine salvage from the host purine pool. Purine starvation as an antimalarial target has been validated by inhibition of purine nucle
Autor:
Josef Thalhamer, Arnulf Hartl, Peter Valent, Steve C. Almo, Rudolf Valenta, Alexander A. Fedorov, Walter Keller, Petra Verdino, Tanja Ball, Jolanta Kopec, Wolfgang R. Sperr, Margarete Focke, Susanne Vrtala
Publikováno v:
Europe PubMed Central
Scopus-Elsevier
Scopus-Elsevier
On the basis of IgE epitope mapping data, we have produced three allergen fragments comprising aa 1–33, 1–57, and 31–110 of the major timothy grass pollen allergen Phl p 6 aa 1–110 by expression in Escherichia coli and chemical synthesis. Cir
Autor:
R. Thirumuruhan, Chenyang Zhan, Udupi A. Ramagopal, Steve C. Almo, Babu A. Manjasetty, Mark R. Chance, Wuxian Shi, Alexander A. Fedorov, Andras Fiser, Elena V. Fedorov
Publikováno v:
Acta Crystallographica Section F Structural Biology and Crystallization Communications. 61:959-963
The three-dimensional crystallographic structure of the ybeY protein from Escherichia coli (SwissProt entry P77385) is reported at 2.7 A resolution. YbeY is a hypothetical protein that belongs to the UPF0054 family. The structure reveals that the pro
Autor:
Andras Muhlrad, Andrey A. Bobkov, Emil Reisler, Dmitry S. Kudryashov, Steve C. Almo, Y. Michael Peyser
Publikováno v:
Journal of Molecular Biology. 342:1559-1567
Cofilin/ADF affects strongly the structure of actin filaments and especially the intermolecular contacts of the DNase I binding loop (D-loop) in subdomain 2. In G-actin, the D-loop is cleaved by subtilisin between Met47 and Gly48, while in F-actin th