Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Steve Busch"'
Autor:
Kameran Wong, Ray Wickenheiser, Rachel Oefelein, Swathi Kumar, Mandi Van Buren, Steve Kramer, Steve Busch
Publikováno v:
Forensic Science International: Synergy, Vol 6, Iss , Pp 100370- (2023)
Externí odkaz:
https://doaj.org/article/c3fb52f101ff476fa04ef389d61edd96
Autor:
Diane E. Gunson, Phil Bentley, Michael Hayes, Elizabeth Skuba, Peter Hoffmann, Dan Lapadula, Steve Busch, Lori Martin, Michael Keselica
Publikováno v:
Toxicologic Pathology. 45:76-83
This article describes acute toxicity data in cynomolgus monkeys following oral treatment with vildagliptin, a dipeptidyl peptidase-4 inhibitor. Acute toxicity symptoms in cynomolgus monkeys include edema formation of the extremities, tails, and face
Autor:
Nick Flavahan, Linda Longo, Pierre Moulin, Wei Zhou, Valerie Dubost, Pritam S. Sahota, Lori Martin, Robert H. Spaet, Serafino Pantano, Heidi A. Schoenfeld, Bryan Burkey, Dan Lapadula, Virendar K. Kaushik, Phil Bentley, Salah-Dine Chibout, Peter Hoffmann, Michael Hayes, Steve Busch
Publikováno v:
Toxicologic Pathology. 42:684-695
The purpose of this article is to characterize skin lesions in cynomolgus monkeys following vildagliptin (dipeptidyl peptidase-4 inhibitor) treatment. Oral vildagliptin administration caused dose-dependent and reversible blister formation, peeling an
Autor:
Armin Wolf, Francois Pognan, Nandita Shangari, Lee Anne McLean, Elba Cruz, Parul Patel, Salah-Dine Chibout, Shruthi Sampath, Pierre Moulin, Steve Busch, Chiara Buono, Albert Reising, Maya Gurnani
Publikováno v:
Toxicological Sciences
Toxicological Sciences; Vol 126
Toxicological Sciences; Vol 126
Lens explant cultures were used to assess the mechanism of drug-induced cataractogenic potential of NVS001, a peroxisome proliferator-activated receptor delta (PPARδ) agonist, which resulted in cataract in all treated animals during a 13-week rat st
Publikováno v:
SAE International Journal of Engines. 2:40-47
Publikováno v:
International Journal of Leadership in Education. 12:73-84
The purpose of the study was to investigate whether Exemplary, Recognized and Acceptable schools differ in their school climates, as measured by the 10 dimensions of the Organizational Health Inventory. Significant differences were found on all 10 di
Autor:
Paul B. Rothman, Steve Busch, Charles A. Powell, Jerome S. Brody, Jeanine D'Armiento, Mariana Capurro, Jennifer Lange, Han Kim, Jorge Filmus, Alain C. Borczuk, Guoliang Xu
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 29:694-701
Recently, we used gene expression profiling of lung adenocarcinoma and paired normal tissue from smokers and nonsmokers to identify genes and molecular pathways associated with cigarette smoking and lung carcinogenesis. The gene encoding Glypican 3,
Autor:
Steve Busch, Charles DeLisi, Charles A. Powell, Avrum Spira, William G. Richards, Jerome S. Brody, Adnan Derti, Raphael Bueno, Sudhir Sahasrabudhe, Yangde Chen, Gang Liu, Alain C. Borczuk, David J. Sugarbaker
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 29:157-162
Adenocarcinoma (AC) has become the most frequent type of lung cancer in men and women, and is the major form of lung cancer in nonsmokers. Our goal in this paper was to determine if AC in smokers and nonsmokers represents the same genetic disease. We
Autor:
Michael C. Milone, Elizabeth Skuba, Daher Ibrahim Aibo, LeeAnne Talbot, Regina M. Young, Lori Martin, Vijay Bhoj, Steve Busch, Saar Gill, Jennifer Marlowe, Timothy K. MacLachlan, Linda Dong, Olga Shestova, Celeste Richardson, Xiaorui Yao
Publikováno v:
Molecular Therapy. 24:S158
The CAR-T platform has provided an exceptionally potent means to treat cancers that have proven resistant to standard treatments. This potency, however, can work against normal tissue as well. Some clinical trials have identified adverse consequences
Autor:
Michael Merz, André Cordier, Pierre Moulin, Jonathan G. Moggs, David J. Heard, Michele Leonard, Francois Pognan, Page Bouchard, Steve Busch, Salah-Dine Chibout, Michael Kammüller, Dominique Brees
Publikováno v:
Expert opinion on drug metabolismtoxicology. 8(9)
Following a US National Academy of Sciences report in 2007 entitled "Toxicity Testing of the 21st Century: a Vision and a Strategy," significant advances within translational drug safety sciences promise to revolutionize drug discovery and developmen