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Autor:
Peilin Yu, Susan H. Hardin, Brent A. Mulder, Steve Anaya, Richard C. Willson, Keun Woo Lee, James M. Briggs, Jason C. Murphy, Anvy Nguyen, Xiaolian Gao
Publikováno v:
Nucleic Acids Research
The mechanism by which HIV-1 reverse transcriptase (HIV-RT) discriminates between the correct and incorrect nucleotide is not clearly understood. Chemically modified nucleotides containing 1-aminonaphthalene-5-sulfonate (ANS) attached to their gamma-