Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Steve A. Edgley"'
Publikováno v:
The Journal of Neuroscience
Early evolution of the motor cortex included development of connections to brainstem reticulospinal neurons; these projections persist in primates. In this study, we examined the organization of corticoreticular connections in five macaque monkeys (o
Publikováno v:
Brain
Damage to the corticospinal tract is a leading cause of motor disability, for example in stroke or spinal cord injury. Some function usually recovers, but whether plasticity of undamaged ipsilaterally descending corticospinal axons and/or brainstem p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180db13008ca2313f76093b21138b9e7
Publikováno v:
The Journal of Neuroscience
Renshaw cells mediate recurrent inhibition between motoneurons within the spinal cord. The function of this circuit is not clear; we previously suggested based on computational modeling that it may cancel oscillations in muscle activity around 10 Hz,
Publikováno v:
The Journal of Physiology. 591:1045-1062
Key points • The lateral reticular nucleus (LRN) sends dense mossy fibre projections to the cerebellum. We report that LRN neurons convey timing signals that, along with measurements of force and distance, are needed for the cerebellum to organise
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 36(9)
Previous anatomical work in primates has suggested that only corticospinal axons originating in caudal primary motor cortex ("new M1") and area 3a make monosynaptic cortico-motoneuronal connections with limb motoneurons. By contrast, the more rostral
Publikováno v:
The Journal of Neuroscience. 31:11208-11219
Strong experimental evidence implicates the corticospinal tract in voluntary control of the contralateral forelimb. Its potential role in controlling the ipsilateral forelimb is less well understood, although anatomical projections to ipsilateral spi
Autor:
Steve A. Edgley, Oivier Frey, Tian Zhao, Nico F. de Rooij, Tahl Holtzman, Peter D. van der Wal, Jeffrey W. Dalley, Vanessa Sivam
Publikováno v:
The Journal of Physiology. 589:3837-3854
Despite a wealth of in vitro and modelling studies it remains unclear how neuronal populations in the cerebellum interact in vivo. We address the issue of how the cerebellar input layer processes sensory information, with particular focus on the gran
Autor:
Steve A. Edgley, Elzbieta Jankowska
Publikováno v:
European Journal of Neuroscience. 32:881-893
A first step towards understanding the operation of a neural network is identification of the populations of neurons that contribute to it. Our aim here is to reassess the basis for subdivision of adult mammalian spinal interneurons that mediate refl
Autor:
Steve A. Edgley, Wei Xu
Publikováno v:
European Journal of Neuroscience. 32:591-597
Golgi cells are important players in the function of the cerebellar cortex, controlling the flow of incoming information from mossy fibres to the granule cells, which excite other cortical neurons. We recently showed that in anaesthetized rats most G
Publikováno v:
Journal of Neuroscience. 30:8920-8934
The classically conditioned eyeblink response in the rabbit is one of the best-characterized behavioral models of associative learning. It is cerebellum dependent, with many studies indicating that the hemispheral part of Larsell's cerebellar cortica