Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Steve A Ward"'
Autor:
David J Bell, Suzgo K Nyirongo, Mavuto Mukaka, Ed E Zijlstra, Christopher V Plowe, Malcolm E Molyneux, Steve A Ward, Peter A Winstanley
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1578 (2008)
In Malawi, there has been a return of Plasmodium falciparum sensitivity to chloroquine (CQ) since sulfadoxine-pyrimethamine (SP) replaced CQ as first line treatment for uncomplicated malaria. When used for prophylaxis, Amodiaquine (AQ) was associated
Externí odkaz:
https://doaj.org/article/827ae775f86b48e8bf74ea4dd2f16fe0
Publikováno v:
Progress in Disaster Science, Vol 12, Iss , Pp 100191- (2021)
A promising tsunami warning system outlined here links Total Electron Content (TEC) disturbances in the ionosphere detected by GNSS satellites to maps of inundated areas along the affected coastlines. This will be accomplished through a pipeline of e
Externí odkaz:
https://doaj.org/article/dff5e26b7f95422086df6338d4d6d6f2
Autor:
Samantha Donnellan, Shaun H Pennington, Alessandra Ruggiero, Carmen Martinez-Rodriguez, Marion Pouget, Jordan Thomas, Steve A Ward, Georgios Pollakis, Giancarlo A Biagini, William A Paxton
Mycobacterium tuberculosis and human immunodeficiency virus-1 (HIV-1) syndemic interactions are a major global health concern. Despite the clinical significance of coinfection, our understanding of the cellular pathophysiology and the therapeutic pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52582433eac0f3039d35d4d1be86167c
https://hdl.handle.net/11562/1085557
https://hdl.handle.net/11562/1085557
Autor:
Doris Shani, Saye Khoo, Henry C. Mwandumba, Derek J. Sloan, Steve A. Ward, Frank Kloprogge, Gertrude Banda, Nadia Kontogianni, Mercy Kamdolozi, Geraint Davies, Elizabeth L. Corbett
Publikováno v:
Open Forum Infectious Diseases
OPEN FORUM INFECTIOUS DISEASES
OPEN FORUM INFECTIOUS DISEASES
Background This study aims to explore relationships between baseline demographic covariates, plasma antibiotic exposure, sputum bacillary load, and clinical outcome data to help improve future tuberculosis (TB) treatment response predictions. Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970834d14df4340c6b655a969b5971c3
Autor:
Neill J. Liptrott, Usman Arshad, Shaun H. Pennington, Paul Curley, Andrew F. Hill, Paul M. O'Neill, Saye Khoo, Andrew Owen, Lee Tatham, Weiqian David Hong, Anthony Valentijn, Henry Pertinez, Ghaith Aljayyoussi, Steve A. Ward, Helen Box, Megan Neary, Christopher David, Rajith K. R. Rajoli, Patrick G. Bray, Steven Paul Rannard, Giancarlo A. Biagini, Joanne Sharp, Marta Boffito
Publikováno v:
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
British Journal of Clinical Pharmacology
medRxiv
Authorea, Inc.
British Journal of Clinical Pharmacology
medRxiv
Authorea, Inc.
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been declared a global pandemic by the World Health Organisation and urgent treatment and prevention strategies are needed. Many clinical trials have been initiated with exist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc7778a73fd15536c6c10511e20bea7
Autor:
Peter Horby, Janet T Scott, Steve A. Ward, Ian Goodfellow, Foday Sahr, Catrin E. Moore, Raman Sharma, Rapide-Tkm trial team, Luke Meredith, Jake Dunning
Publikováno v:
Access Microbiology. 2
TKM-130803 is a specific anti-EBOV therapeutic comprising of two small interfering RNAs (siRNA) siLpol-2 and siVP35-2. The pharmacokinetics (PK) of these siRNAs was defined in Ebola virus disease (EVD) patients. The relationship between PK and patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebaa792deaa578372af414f9ce1157c4
https://doi.org/10.1099/acmi.fis2019.po0042
https://doi.org/10.1099/acmi.fis2019.po0042
Autor:
Steve A. Ward, Foday Sahr, Peter Horby, Ian Goodfellow, Catrin E. Moore, Janet T Scott, Raman Sharma, Luke W. Meredith, Jake Dunning
Publikováno v:
EBioMedicine
EBioMedicine, Vol 52, Iss, Pp-(2020)
EBioMedicine, Vol 52, Iss, Pp-(2020)
Background: \ud TKM-130803 is a specific anti-EBOV therapeutic comprised of two small interfering RNAs (siRNA) siLpol-2 and siVP35-2. The pharmacokinetics (PK) of these siRNAs was defined in Ebola virus disease (EVD) patients, with reference to effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0e6a1fbd627698a13d5058d9b8e552
https://eprints.gla.ac.uk/209248/1/209248.pdf
https://eprints.gla.ac.uk/209248/1/209248.pdf
Autor:
Simon Kariuki, Titus K. Kwambai, Tao Chen, Menno R. Smit, Hannah C Slater, Aaron M. Samuels, Teun Bousema, Feiko O. ter Kuile, Duolao Wang, Ghaith Aljayyoussi, John E. Gimnig, Bernard O. Abong'o, Meghna Desai, Steve A. Ward, David Waterhouse, Penelope A. Phillips-Howard, Nabie Bayoh, Eric Ochomo
Publikováno v:
Lancet Infectious Diseases, 18, 6, pp. 615-639
Parasite
Smit, M R, Ochomo, E O, Aljayyoussi, G, Kwambai, T K, Abong'o, B O, Chen, T, Bousema, T, Slater, H C, Waterhouse, D, Bayoh, N M, Gimnig, J E, Samuels, A M, Desai, M R, Phillips-Howard, P A, Kariuki, S K, Wang, D, Ward, S A & ter Kuile, F O 2018, ' Safety and mosquitocidal efficacy of high-dose ivermectin when co-administered with dihydroartemisinin-piperaquine in Kenyan adults with uncomplicated malaria (IVERMAL) : a randomised, double-blind, placebo-controlled trial ', The Lancet Infectious Diseases, vol. 18, no. 6, pp. 615-626 . https://doi.org/10.1016/S1473-3099(18)30163-4
The Lancet Infectious Diseases, 18(6), 615-626. Lancet Publishing Group
Lancet Infectious Diseases, 18, 615-639
Parasite
Smit, M R, Ochomo, E O, Aljayyoussi, G, Kwambai, T K, Abong'o, B O, Chen, T, Bousema, T, Slater, H C, Waterhouse, D, Bayoh, N M, Gimnig, J E, Samuels, A M, Desai, M R, Phillips-Howard, P A, Kariuki, S K, Wang, D, Ward, S A & ter Kuile, F O 2018, ' Safety and mosquitocidal efficacy of high-dose ivermectin when co-administered with dihydroartemisinin-piperaquine in Kenyan adults with uncomplicated malaria (IVERMAL) : a randomised, double-blind, placebo-controlled trial ', The Lancet Infectious Diseases, vol. 18, no. 6, pp. 615-626 . https://doi.org/10.1016/S1473-3099(18)30163-4
The Lancet Infectious Diseases, 18(6), 615-626. Lancet Publishing Group
Lancet Infectious Diseases, 18, 615-639
Background: Ivermectin is being considered for mass drug administration for malaria due to its ability to kill mosquitoes feeding on recently treated individuals. However, standard, single doses of 150–200 μg/kg used for onchocerciasis and lymphat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c253d302d4460754faf1ad8d1960e40
https://doi.org/10.1016/s1473-3099(18)30163-4
https://doi.org/10.1016/s1473-3099(18)30163-4
Autor:
Gerry Davies, Alessandro Schipani, Elizabeth Molyneux, Steve A. Ward, Rachel Mlota, Fraction K. Dzinjalamala, Saye Khoo, Henry Pertinez, Joep J. van Oosterhout, Nuria Lopez
Publikováno v:
British Journal of Clinical Pharmacology. 81:679-687
AIMS Low rifampicin plasma concentrations can lead to treatment failure and increased risk of developing drug resistant tuberculosis. The objectives of this study were to characterize the population pharmacokinetics (popPK) of rifampicin in Malawian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04d56fce15bc3bcee396e326d20b6d38
https://doi.org/10.1111/bcp.12848
https://doi.org/10.1111/bcp.12848
Novel anti-Wolbachia drugs, a new approach in the treatment and prevention of veterinary filariasis?
Publikováno v:
Veterinary Parasitology. 279:109057
Filarial nematodes are tissue-dwelling parasitic worms that can cause a range of disfiguring pathologies in humans and potentially lethal infections of companion animals. The bacterial endosymbiont, Wolbachia, is present within most human and veterin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3eed70f17a48a8d33d033bd1b5dfbef
https://doi.org/10.1016/j.vetpar.2020.109057
https://doi.org/10.1016/j.vetpar.2020.109057