Zobrazeno 1 - 10 of 293 pro vyhledávání: '"Steve A Ward"'
1
Akademický článek
Tsunami Squares: Earthquake driven inundation mapping and validation by comparison to the Regional Ocean Modeling System
Autor: David P. Grzan, John B. Rundle, John M. Wilson, Tony Song, Steve N. Ward, Andrea Donnellan
Publikováno v: Progress in Disaster Science, Vol 12, Iss , Pp 100191- (2021)
A promising tsunami warning system outlined here links Total Electron Content (TEC) disturbances in the ionosphere detected by GNSS satellites to maps of inundated areas along the affected coastlines. This will be accomplished through a pipeline of e
Externí odkaz: https://doaj.org/article/dff5e26b7f95422086df6338d4d6d6f2
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3
A quantitative method for the study of HIV-1 and Mycobacterium tuberculosis co-infection
Autor: Samantha Donnellan, Shaun H Pennington, Alessandra Ruggiero, Carmen Martinez-Rodriguez, Marion Pouget, Jordan Thomas, Steve A Ward, Georgios Pollakis, Giancarlo A Biagini, William A Paxton
Mycobacterium tuberculosis and human immunodeficiency virus-1 (HIV-1) syndemic interactions are a major global health concern. Despite the clinical significance of coinfection, our understanding of the cellular pathophysiology and the therapeutic pha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52582433eac0f3039d35d4d1be86167c
https://hdl.handle.net/11562/1085557
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4
Akademický článek
Advances in Nephelometry through the Ecotech Aurora Nephelometer
Autor: Steve Chamberlain-Ward, Felicity Sharp
Publikováno v: The Scientific World Journal, Vol 11, Pp 2530-2535 (2011)
The challenge for instrument manufacturers is to continuously improve and evolve their instrumentation to keep pace with scientific research. One field where this is evident is atmospheric aerosol research. The variety in aerosol size, shape, chemica
Externí odkaz: https://doaj.org/article/92ab48df8de944fca0ba2bfa7b314e3a
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5
Longitudinal Pharmacokinetic-Pharmacodynamic Biomarkers Correlate With Treatment Outcome in Drug-Sensitive Pulmonary Tuberculosis: A Population Pharmacokinetic-Pharmacodynamic Analysis
Autor: Doris Shani, Saye Khoo, Henry C. Mwandumba, Derek J. Sloan, Steve A. Ward, Frank Kloprogge, Gertrude Banda, Nadia Kontogianni, Mercy Kamdolozi, Geraint Davies, Elizabeth L. Corbett
Publikováno v: Open Forum Infectious Diseases
OPEN FORUM INFECTIOUS DISEASES
Background This study aims to explore relationships between baseline demographic covariates, plasma antibiotic exposure, sputum bacillary load, and clinical outcome data to help improve future tuberculosis (TB) treatment response predictions. Methods
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970834d14df4340c6b655a969b5971c3
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6
Dose prediction for repurposing nitazoxanide in SARS-CoV-2 treatment or chemoprophylaxis
Autor: Neill J. Liptrott, Usman Arshad, Shaun H. Pennington, Paul Curley, Andrew F. Hill, Paul M. O'Neill, Saye Khoo, Andrew Owen, Lee Tatham, Weiqian David Hong, Anthony Valentijn, Henry Pertinez, Ghaith Aljayyoussi, Steve A. Ward, Helen Box, Megan Neary, Christopher David, Rajith K. R. Rajoli, Patrick G. Bray, Steven Paul Rannard, Giancarlo A. Biagini, Joanne Sharp, Marta Boffito
Publikováno v: BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
British Journal of Clinical Pharmacology
medRxiv
Authorea, Inc.
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been declared a global pandemic by the World Health Organisation and urgent treatment and prevention strategies are needed. Many clinical trials have been initiated with exist
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc7778a73fd15536c6c10511e20bea7
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7
Pharmacokinetics of TKM-130803 in Ebola virus disease in Sierra Leonean subjects
Autor: Peter Horby, Janet T Scott, Steve A. Ward, Ian Goodfellow, Foday Sahr, Catrin E. Moore, Raman Sharma, Rapide-Tkm trial team, Luke Meredith, Jake Dunning
Publikováno v: Access Microbiology. 2
TKM-130803 is a specific anti-EBOV therapeutic comprising of two small interfering RNAs (siRNA) siLpol-2 and siVP35-2. The pharmacokinetics (PK) of these siRNAs was defined in Ebola virus disease (EVD) patients. The relationship between PK and patien
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebaa792deaa578372af414f9ce1157c4
https://doi.org/10.1099/acmi.fis2019.po0042
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8
Pharmacokinetics of TKM-130803 in Sierra Leonean patients with Ebola virus disease: plasma concentrations exceed target levels, with drug accumulation in the most severe patients
Autor: Steve A. Ward, Foday Sahr, Peter Horby, Ian Goodfellow, Catrin E. Moore, Janet T Scott, Raman Sharma, Luke W. Meredith, Jake Dunning
Publikováno v: EBioMedicine
EBioMedicine, Vol 52, Iss, Pp-(2020)
Background: \ud TKM-130803 is a specific anti-EBOV therapeutic comprised of two small interfering RNAs (siRNA) siLpol-2 and siVP35-2. The pharmacokinetics (PK) of these siRNAs was defined in Ebola virus disease (EVD) patients, with reference to effic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c0e6a1fbd627698a13d5058d9b8e552
https://eprints.gla.ac.uk/209248/1/209248.pdf
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9
Safety and mosquitocidal efficacy of high-dose ivermectin when co-administered with dihydroartemisinin-piperaquine in Kenyan adults with uncomplicated malaria (IVERMAL): a randomised, double-blind, placebo-controlled trial
Autor: Simon Kariuki, Titus K. Kwambai, Tao Chen, Menno R. Smit, Hannah C Slater, Aaron M. Samuels, Teun Bousema, Feiko O. ter Kuile, Duolao Wang, Ghaith Aljayyoussi, John E. Gimnig, Bernard O. Abong'o, Meghna Desai, Steve A. Ward, David Waterhouse, Penelope A. Phillips-Howard, Nabie Bayoh, Eric Ochomo
Publikováno v: Lancet Infectious Diseases, 18, 6, pp. 615-639
Parasite
Smit, M R, Ochomo, E O, Aljayyoussi, G, Kwambai, T K, Abong'o, B O, Chen, T, Bousema, T, Slater, H C, Waterhouse, D, Bayoh, N M, Gimnig, J E, Samuels, A M, Desai, M R, Phillips-Howard, P A, Kariuki, S K, Wang, D, Ward, S A & ter Kuile, F O 2018, ' Safety and mosquitocidal efficacy of high-dose ivermectin when co-administered with dihydroartemisinin-piperaquine in Kenyan adults with uncomplicated malaria (IVERMAL) : a randomised, double-blind, placebo-controlled trial ', The Lancet Infectious Diseases, vol. 18, no. 6, pp. 615-626 . https://doi.org/10.1016/S1473-3099(18)30163-4
The Lancet Infectious Diseases, 18(6), 615-626. Lancet Publishing Group
Lancet Infectious Diseases, 18, 615-639
Background: Ivermectin is being considered for mass drug administration for malaria due to its ability to kill mosquitoes feeding on recently treated individuals. However, standard, single doses of 150–200 μg/kg used for onchocerciasis and lymphat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c253d302d4460754faf1ad8d1960e40
https://doi.org/10.1016/s1473-3099(18)30163-4
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10
Akademický článek
Sulfadoxine-pyrimethamine-based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in Malawi.
Autor: David J Bell, Suzgo K Nyirongo, Mavuto Mukaka, Ed E Zijlstra, Christopher V Plowe, Malcolm E Molyneux, Steve A Ward, Peter A Winstanley
Publikováno v: PLoS ONE, Vol 3, Iss 2, p e1578 (2008)
In Malawi, there has been a return of Plasmodium falciparum sensitivity to chloroquine (CQ) since sulfadoxine-pyrimethamine (SP) replaced CQ as first line treatment for uncomplicated malaria. When used for prophylaxis, Amodiaquine (AQ) was associated
Externí odkaz: https://doaj.org/article/827ae775f86b48e8bf74ea4dd2f16fe0
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