Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Steve, Roffler"'
Autor:
Jiho Kim, Chang Li, Hongjie Wang, Swarnendu Kaviraj, Sanjay Singh, Laxman Savergave, Arjun Raghuwanshi, Sucheol Gil, Audrey Germond, Audrey Baldessari, Bingmae Chen, Steve Roffler, Pascal Fender, Charles Drescher, Darrick Carter, André Lieber
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Our goal is to overcome treatment resistance in ovarian cancer patients which occurs in most cases after an initial positive response to chemotherapy. A central resistance mechanism is the maintenance of desmoglein-2 (DSG2) positive tight ju
Externí odkaz:
https://doaj.org/article/f750a078157146a4b349ea4bf8b95d18
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112502- (2022)
Antibodies that bind polyethylene glycol (PEG) can be induced by pegylated biomolecules and also exist in a significant fraction of healthy individuals who have never received pegylated medicines. The binding affinity of antibodies against PEG (anti-
Externí odkaz:
https://doaj.org/article/370a0caeb29b4be5863b7f130df53668
Autor:
Yaelle, Bavli, Bing-Mae, Chen, Guy, Gross, Alon, Hershko, Keren, Turjeman, Steve, Roffler, Yechezkel, Barenholz
Publikováno v:
Journal of Controlled Release. 354:316-322
The early and massive vaccination campaign in Israel with the mRNA-LNP Comirnaty® (Pfizer-BioNTech) vaccine against the SARS-CoV-2 virus made available large amounts of data regarding the efficacy and safety of this vaccine. Adverse reactions to mRN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1dfd9494c44e199cbfcb24e4160653d
https://doi.org/10.1016/j.jconrel.2022.12.039
https://doi.org/10.1016/j.jconrel.2022.12.039
Autor:
André Lieber, Charles Drescher, Steve Roffler, Darrick Carter, Ronald Berenson, Zongyi Li, Ruan van Rensburg, Roma Yumul, Qinghua Feng, Maximilian Richter, Hui Song, Jonas Persson, Hua Cao, Ines Beyer
Purpose: Epithelial junctions between tumor cells inhibit the penetration of anticancer drugs into tumors. We previously reported on recombinant adenovirus serotype 3–derived protein (JO-1), which triggers transient opening of intercellular junctio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837cbef618d001949edbf2366079da52
https://doi.org/10.1158/1078-0432.c.6522171.v1
https://doi.org/10.1158/1078-0432.c.6522171.v1
Autor:
André Lieber, Charles Drescher, Steve Roffler, Darrick Carter, Ronald Berenson, Zongyi Li, Ruan van Rensburg, Roma Yumul, Qinghua Feng, Maximilian Richter, Hui Song, Jonas Persson, Hua Cao, Ines Beyer
PDF file - 55K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b1f631ae197b7c6d2af8e9c4756406e
https://doi.org/10.1158/1078-0432.22451325
https://doi.org/10.1158/1078-0432.22451325
Autor:
Mansoureh Z. Mousavi, Huai-Yi Chen, Hsien-San Hou, Chou-Yuan-Yuan Chang, Steve Roffler, Pei-Kuen Wei, Ji-Yen Cheng
Publikováno v:
Biosensors, Vol 5, Iss 1, Pp 98-117 (2015)
Label-free detection of rare cells in biological samples is an important and highly demanded task for clinical applications and various fields of research, such as detection of circulating tumor cells for cancer therapy and stem cells studies. Surfac
Externí odkaz:
https://doaj.org/article/936ad04226df419a83508addc2b17fc6
Autor:
Maximilian Richter, Roma Yumul, Hongjie Wang, Kamola Saydaminova, Martin Ho, Drew May, Audrey Baldessari, Michael Gough, Charles Drescher, Nicole Urban, Steve Roffler, Chloé Zubieta, Darrick Carter, Pascal Fender, André Lieber
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 2, Iss , Pp - (2015)
A central treatment resistance mechanism in solid tumors is the maintenance of epithelial junctions between malignant cells that prevent drug penetration into the tumor. We have developed a small recombinant protein (JO-1) that triggers the transient
Externí odkaz:
https://doaj.org/article/50012c0aed7f41bb85ff4d5891529a9f
Autor:
Jer-Yuarn Wu, Bing-Mae Chen, Yi-Wen Chiu, Pei-Hua Yu, Tian-Lu Cheng, Daw-Yang Hwang, Tien-Ching Chang, And Steve Roffler, Yuan-Tsong Chen, Wen-Wei Lin
Publikováno v:
Pharmaceutics
Volume 12
Issue 1
Volume 12
Issue 1
Pre-existing antibodies that bind polyethylene glycol are present in about 40% of healthy individuals. It is currently unknown if pre-existing anti-polyethylene glycol (PEG) antibodies can alter the bioactivity of pegylated drugs with a single long P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dd19defbcdb6c5e08a5d4012776a54e
Autor:
Jonas Persson, Ines Beyer, Roma Yumul, ZongYi Li, Hans-Peter Kiem, Steve Roffler, André Lieber
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22303 (2011)
Monoclonal antibodies specific for cytotoxic T lymphocyte-associated antigen 4 (anti-CTLA4) are a novel form of cancer immunotherapy. While preclinical studies in mouse tumor models have shown anti-tumor efficacy of anti-CTLA4 injection or expression
Externí odkaz:
https://doaj.org/article/4d87b301d3fc48b78a9f3c76a4946082
Autor:
Mousavi, Mansoureh Z., Huai-Yi Chen, Hsien-San Hou, Chou-Yuan-Yuan Chang, Steve Roffler, Pei-Kuen Wei, Ji-Yen Cheng
Publikováno v:
Biosensors (2079-6374); 2015, Vol. 5 Issue 1, p98-117, 20p