Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Steve, Meaney"'
Autor:
Christopher J. Law, Steve Meaney
Publikováno v:
Experimental Results, Vol 3 (2022)
The phenomenon of antimicrobial resistance represents a major public health risk. The activity of integral membrane transporter proteins contributes to antimicrobial resistance in pathogenic bacteria and proton gradient-driven multidrug efflux repres
Externí odkaz:
https://doaj.org/article/38b60e841f6f4e6da3bfba6a4915e336
Publikováno v:
Experimental Results, Vol 3 (2022)
The unfolded protein response has recently been implicated as a mechanism by which 1,10-phenanthroline-containing coordination compounds trigger cell death. We explored the interaction of two such compounds—one containing copper and one containing
Externí odkaz:
https://doaj.org/article/77475985196b4fbfb1cf047c30068a1d
Publikováno v:
Marine Drugs, Vol 20, Iss 5, p 317 (2022)
Over the last decade, algae have been explored as alternative and sustainable protein sources for a balanced diet and more recently, as a potential source of algal-derived bioactive peptides with potential health benefits. This review will focus on t
Externí odkaz:
https://doaj.org/article/3d0e043a48f641d3bb7f3cb6bdd36839
Publikováno v:
Molecules, Vol 25, Iss 8, p 2005 (2020)
Seaweeds are a rich source of protein and can contain up to 47% on the dry weight basis. It is challenging to extract proteins from the raw biomass of seaweed due to resilient cell-wall complexes. Four species of macroalgae were used in this study-tw
Externí odkaz:
https://doaj.org/article/96e431ba5b6d4a2cba94a56695d41ce1
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 9, Pp 2489-2503 (2010)
Cholesterol is an essential component of both the peripheral and central nervous systems of mammals. Over the last decade, evidence has accumulated that disturbances in cholesterol metabolism are associated with the development of various neurologica
Externí odkaz:
https://doaj.org/article/1134b68b5793490684481921e83fee9a
Autor:
Steve Meaney, Maura Heverin, Ute Panzenboeck, Lena Ekström, Magnus Axelsson, Ulla Andersson, Ulf Diczfalusy, Irina Pikuleva, John Wahren, Wolfgang Sattler, Ingemar Björkhem
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 4, Pp 944-951 (2007)
Recently, we demonstrated a net blood-to-brain passage of the oxysterol 27-hydroxycholesterol corresponding to 4–5 mg/day. As the steady-state levels of this sterol are only 1–2 μg/g brain tissue, we hypothesized that it is metabolized and subse
Externí odkaz:
https://doaj.org/article/29855b943bef4c258274a21859ee3155
Autor:
Maura Heverin, Steve Meaney, Dieter Lütjohann, Ulf Diczfalusy, John Wahren, Ingemar Björkhem
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 5, Pp 1047-1052 (2005)
Side chain oxidizedoxysterols have a unique ability to traverse lipophilic membranes. We tested thehypothesis that there is a net flux of 27-hydroxycholesterol from the circulationinto the brain using plasma samples collected from the internal jugula
Externí odkaz:
https://doaj.org/article/11447fbf52b84111a71954b3b98ffed5
Autor:
Steve Meaney, Tracey L. Bonfield, Magnus Hansson, Amir Babiker, Mani S. Kavuru, Mary Jane Thomassen
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 12, Pp 2354-2360 (2004)
The conversion of cholesterol into the more polar metabolites 27-hydroxycholesterol (27-OH) and cholestenoic acid by the cytochrome P450 sterol 27-hydroxylase is a cholesterol-removal mechanism used by almost all cells. Most of the cholestenoic acid
Externí odkaz:
https://doaj.org/article/4d48a246a92b45fda1a6ed4719d995a0
Publikováno v:
Journal of Lipid Research, Vol 44, Iss 4, Pp 793-799 (2003)
The side chain oxidized oxysterol 24S-hydroxycholesterol (24-OH-chol) is formed almost exclusively in the brain, and there is a continuous passage of this oxysterol through the circulation to the liver. 27-Hydroxycholesterol (27-OH-chol) is produced
Externí odkaz:
https://doaj.org/article/fa6ec99c0a8c46fa8b2d49b6ba011426
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 12, Pp 2130-2135 (2002)
Oxysterols possess powerful biological activities. Some of their effects on the regulation of key enzymes are similar to those of cholesterol, but are much more potent. One of the critical properties of oxysterols is their ability to pass lipophilic
Externí odkaz:
https://doaj.org/article/e9ca9175657c495499984a61d83ba249