Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Stevan Shaw"'
Autor:
Suzanne Cole, Janine Murray, Catherine Simpson, Remi Okoye, Kerry Tyson, Meryn Griffiths, Dominique Baeten, Stevan Shaw, Asher Maroof
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for inducing IL-17 production in other human immune subsets remains incompletely understood. Mucosal associated invariant T (MAIT) cells uniformly express retin
Externí odkaz:
https://doaj.org/article/9977591d4c7042d0b21fe34563635126
Autor:
Dominique Baeten, Stevan Shaw, Mittal Shah, Asher Maroof, Panos Gikas, Gayatri Mittal, Richard Keen, Scott J Roberts
Publikováno v:
RMD Open, Vol 6, Iss 2 (2020)
Objectives Interleukin (IL)-17 signalling has been shown to be a key regulator of disease in ankylosing spondylitis (AS) with several IL-17 blockers currently clinically approved. Despite this, the role of IL-17 in bone pathology is poorly understood
Externí odkaz:
https://doaj.org/article/3c4af04ceda542ef8d125c3a054f81d0
Autor:
Ralph Adams, Asher Maroof, Terry Baker, Alastair D. G. Lawson, Ruth Oliver, Ross Paveley, Steve Rapecki, Stevan Shaw, Pavan Vajjah, Shauna West, Meryn Griffiths
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Interleukin (IL)-17A is a key driver of inflammation and the principal target of anti-IL-17 therapeutic monoclonal antibodies. IL-17A, and its structurally similar family member IL-17F, have been shown to be functionally dysregulated in certain human
Externí odkaz:
https://doaj.org/article/b1dbe735c4a147d884a03b1106dffb94
Autor:
Mesias Pedroza, Daniel J Schneider, Harry Karmouty-Quintana, Julie Coote, Stevan Shaw, Rebecca Corrigan, Jose G Molina, Joseph L Alcorn, David Galas, Richard Gelinas, Michael R Blackburn
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22667 (2011)
BackgroundChronic lung diseases are the third leading cause of death in the United States due in part to an incomplete understanding of pathways that govern the progressive tissue remodeling that occurs in these disorders. Adenosine is elevated in th
Externí odkaz:
https://doaj.org/article/55b1329ceccf4e169ad2b50505e6c82d
Autor:
Suzanne Cole, Avneet Manghera, Lachrissa Burns, Janine Barrett, Nicole Yager, Hefin Rhys, Andrew Skelton, John Cole, Carl S. Goodyear, Meryn Griffiths, Dominique Baeten, Marta Bertolini, Stevan Shaw, Hussein Al-Mossawi, Asher Maroof
Publikováno v:
Journal of Allergy and Clinical Immunology.
Autor:
Christopher Sayed, Seth B Forman, Christos C. Zouboulis, Lucian Ionescu, Dominique Baeten, George Schmieder, Sophie Glatt, Seth D Seegobin, Jamie Weisman, Stevan Shaw, R. Rolleri, Gregor B.E. Jemec
Publikováno v:
JAMA dermatology, 157(11), 1279-1288. American Medical Association
JAMA Dermatol
JAMA Dermatol
Importance Hidradenitis suppurativa (HS) is a chronic inflammatory disease with a high burden for patients and limited existing therapeutic options. Objective To evaluate the efficacy and safety of bimekizumab, a monoclonal IgG1 antibody that selecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b4c1d0ed65479af00e672e072431b06
https://pure.amc.nl/en/publications/efficacy-and-safety-of-bimekizumab-in-moderate-to-severe-hidradenitis-suppurativa-a-phase-2-doubleblind-placebocontrolled-randomized-clinical-trial(3a0da2c2-2eb5-44a6-8d23-19510f4b019b).html
https://pure.amc.nl/en/publications/efficacy-and-safety-of-bimekizumab-in-moderate-to-severe-hidradenitis-suppurativa-a-phase-2-doubleblind-placebocontrolled-randomized-clinical-trial(3a0da2c2-2eb5-44a6-8d23-19510f4b019b).html
Autor:
H Edwards, Ash Maroof, A El Baghdady, Xuan Li, Lucian Ionescu, Sandra Garcet, C Mistry, Pavan Vajjah, B Dizier, James G. Krueger, Mark I L Watling, M Page, Ruth Oliver, Sophie Glatt, Dominique Baeten, Stevan Shaw
Publikováno v:
British journal of dermatology. Wiley-Blackwell
Background: Bimekizumab is a monoclonal antibody that selectively inhibits both interleukin (IL)-17A and IL-17F, which is currently under investigation for treatment of moderate-to-severe plaque psoriasis. Maintenance dosing every 4 weeks is well est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c26482ef1ae45a1fc65b42dc0b19857d
https://pure.amc.nl/en/publications/bimekizumab-for-the-treatment-of-moderatetosevere-plaque-psoriasis(2fbd1a03-ee73-4a58-af39-d52b4a5db98c).html
https://pure.amc.nl/en/publications/bimekizumab-for-the-treatment-of-moderatetosevere-plaque-psoriasis(2fbd1a03-ee73-4a58-af39-d52b4a5db98c).html
Autor:
Dominique Baeten, Remi Okoye, Kerry Louise Tyson, Stevan Shaw, C. Simpson, Janine Murray, Meryn Griffiths, Asher Maroof, Suzanne Cole
Publikováno v:
Frontiers in Immunology
Frontiers in immunology, 11:585134. Frontiers Media S.A.
Frontiers in Immunology, Vol 11 (2020)
Frontiers in immunology, 11:585134. Frontiers Media S.A.
Frontiers in Immunology, Vol 11 (2020)
IL-23 is considered a critical regulator of IL-17 in Th17 cells; however, its requirement for inducing IL-17 production in other human immune subsets remains incompletely understood. Mucosal associated invariant T (MAIT) cells uniformly express retin