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Targeting Indoleamine 2,3-Dioxygenase in Cancer Models Using the Novel Small Molecule Inhibitor NTRC 3883-0.

Autor: Grobben Y; Netherlands Translational Research Center B.V., Oss, Netherlands., de Man J; Netherlands Translational Research Center B.V., Oss, Netherlands., van Doornmalen AM; Netherlands Translational Research Center B.V., Oss, Netherlands., Muller M; Netherlands Translational Research Center B.V., Oss, Netherlands., Willemsen-Seegers N; Netherlands Translational Research Center B.V., Oss, Netherlands., Vu-Pham D; Netherlands Translational Research Center B.V., Oss, Netherlands., Mulder WR; Netherlands Translational Research Center B.V., Oss, Netherlands., Prinsen MBW; Netherlands Translational Research Center B.V., Oss, Netherlands., de Wit J; Netherlands Translational Research Center B.V., Oss, Netherlands., Sterrenburg JG; Netherlands Translational Research Center B.V., Oss, Netherlands., van Cauter F; Netherlands Translational Research Center B.V., Oss, Netherlands., den Ouden JE; Department of Obstetrics and Gynaecology, Radboud University Medical Centre, Nijmegen, Netherlands., van Altena AM; Department of Obstetrics and Gynaecology, Radboud University Medical Centre, Nijmegen, Netherlands., Massuger LF; Department of Obstetrics and Gynaecology, Radboud University Medical Centre, Nijmegen, Netherlands., Uitdehaag JCM; Netherlands Translational Research Center B.V., Oss, Netherlands., Buijsman RC; Netherlands Translational Research Center B.V., Oss, Netherlands., Zaman GJR; Netherlands Translational Research Center B.V., Oss, Netherlands.

Publikováno v: Frontiers in immunology [Front Immunol] 2021 Jan 28; Vol. 11, pp. 609490. Date of Electronic Publication: 2021 Jan 28 (Print Publication: 2020).

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model.

Autor: Maia AR; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam., de Man J; Netherlands Translational Research Center B.V., Oss., Boon U; Division of Molecular Pathology and Cancer Genomics Centre., Janssen A; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam., Song JY; Division of Experimental Animal Pathology, The Netherlands Cancer Institute, Amsterdam., Omerzu M; Department of Medical Oncology., Sterrenburg JG; Netherlands Translational Research Center B.V., Oss., Prinsen MB; Netherlands Translational Research Center B.V., Oss., Willemsen-Seegers N; Netherlands Translational Research Center B.V., Oss., de Roos JA; Netherlands Translational Research Center B.V., Oss., van Doornmalen AM; Netherlands Translational Research Center B.V., Oss., Uitdehaag JC; Netherlands Translational Research Center B.V., Oss., Kops GJ; Department of Medical Oncology Department of Cancer Genomics Netherlands, UMC Utrecht, Utrecht, The Netherlands., Jonkers J; Division of Molecular Pathology and Cancer Genomics Centre Department of Cancer Genomics Netherlands, UMC Utrecht, Utrecht, The Netherlands., Buijsman RC; Netherlands Translational Research Center B.V., Oss., Zaman GJ; Netherlands Translational Research Center B.V., Oss guido.zaman@ntrc.nl., Medema RH; Division of Cell Biology, The Netherlands Cancer Institute, Amsterdam Department of Cancer Genomics Netherlands, UMC Utrecht, Utrecht, The Netherlands.

Publikováno v: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2015 Oct; Vol. 26 (10), pp. 2180-92. Date of Electronic Publication: 2015 Jul 07.