Zobrazeno 1 - 10
of 260
pro vyhledávání: '"Sterol response element binding"'
Autor:
Qiufeng Zeng, Shiping Bai, Gregory S. Fraley, Liping Zhu, Xuemei Ding, Keying Zhang, Jianping Wang, Yue Xuan
Publikováno v:
Animal Nutrition
Animal Nutrition, Vol 7, Iss 4, Pp 1258-1270 (2021)
Animal Nutrition, Vol 7, Iss 4, Pp 1258-1270 (2021)
Sinapine derived from cruciferous plants could be converted into trimethylamine by intestinal microbiota. Its metabolite, trimethylamine N-oxide (TMAO), is closely linked to increased risk of cardiovascular disease and fat deposition in mammals. Hens
Autor:
Muhua Yang, Weidong Liu, Christina Pellicane, Christine Sahyoun, Biny K. Joseph, Christina Gallo-Ebert, Melissa Donigan, Devanshi Pandya, Caroline Giordano, Adam Bata, Joseph T. Nickels, Jr.
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 2, Pp 226-238 (2014)
Dysregulation of cholesterol homeostasis is associated with various metabolic diseases, including atherosclerosis and type 2 diabetes. The sterol response element binding protein (SREBP)-2 transcription factor induces the expression of genes involved
Externí odkaz:
https://doaj.org/article/e8ec46e393164b3f89563e1d830de6fa
Autor:
Chie Takahashi-Muto, Rieko Tanaka-Yachi, Tomoya Koike, Kazutaka Sakiya, Mana Nagase, Yoshimni Yabe, Haruka Takeuchi, Chikako Kiyose
Publikováno v:
Journal of Oleo Science. 70:1317-1323
This study aimed to determine if there are anti-inflammatory and anti-obesity effects of sweet basil, an herb, in mice. Sweet basil was administered as a powder to male C57BL/6JJcl mice, which were divided into three groups: the (control [C], high-fa
Publikováno v:
Current Research in Food Science, Vol 4, Iss, Pp 551-556 (2021)
Curcumin, the primary bioactive substance in turmeric, is known to be associated with weight loss. In this study, we employed Caenorhabditis elegans, a well-established in vivo nematode model to explore the role of curcumin in regulating lipid metabo
Akademický článek
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Publikováno v:
Journal of Lipid Research, Vol 53, Iss 11, Pp 2390-2404 (2012)
Prostacyclin and its prostacyclin receptor, the I Prostanoid (IP), play essential roles in regulating hemostasis and vascular tone and have been implicated in a range cardio-protective effects but through largely unknown mechanisms. In this study, th
Externí odkaz:
https://doaj.org/article/2912214bbe23461098e592318a1a7204
Autor:
Masayuki Shimada, Yasuhisa Yamashita, Asako Okamoto, Shingo Tonai, Risa Tanaka, Tomoya Nakanishi, Tomoko Kawai, Joo Yeon Lee, Manami Yamaoka
Publikováno v:
Endocrinology. 162
In the liver, the sterol response element binding protein (SREBP) and the SREBP cleavage-activated protein (SCAP) complex upregulate cholesterol biosynthesis by gene induction of de novo cholesterol synthetic enzymes (Hmgcr, Cyp51, and Dhcr7). Insuli
Publikováno v:
Open Biology, Vol 5, Iss 9 (2015)
We show that phospholipid anabolism does not occur uniformly during the metazoan cell cycle. Transition to S-phase is required for optimal mobilization of lipid precursors, synthesis of specific phospholipid species and endoplasmic reticulum (ER) hom
Externí odkaz:
https://doaj.org/article/bed6b15199054c1995463a69147f90c6
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11057
Winkel, L, Rasmussen, M, Larsen, L, Dalgaard, L T & Nielsen, J H 2022, ' Fetal Programming of the Endocrine Pancreas : Impact of a Maternal Low-Protein Diet on Gene Expression in the Perinatal Rat Pancreas ', International Journal of Molecular Sciences, vol. 23, no. 19, 11057 . https://doi.org/10.3390/ijms231911057
Winkel, L, Rasmussen, M, Larsen, L, Dalgaard, L T & Nielsen, J H 2022, ' Fetal Programming of the Endocrine Pancreas : Impact of a Maternal Low-Protein Diet on Gene Expression in the Perinatal Rat Pancreas ', International Journal of Molecular Sciences, vol. 23, no. 19, 11057 . https://doi.org/10.3390/ijms231911057
In rats, the time of birth is characterized by a transient rise in beta cell replication, as well as beta cell neogenesis and the functional maturation of the endocrine pancreas. However, the knowledge of the gene expression during this period of bet
Autor:
Elaine M. Quinet, Dawn A. Savio, Anita R. Halpern, Liang Chen, Christopher P. Miller, Ponnal Nambi
Publikováno v:
Journal of Lipid Research, Vol 45, Iss 10, Pp 1929-1942 (2004)
Liver X receptors (LXRs) play key roles in the regulation of cholesterol homeostasis by limiting cholesterol accumulation in macrophages within arterial wall lesion sites by a mechanism that includes the upregulation of ATP binding cassette transport
Externí odkaz:
https://doaj.org/article/946c2838a53544d99e8e748c4a7c5dcb