Zobrazeno 1 - 10
of 15 044
pro vyhledávání: '"Steroidogenesis"'
Autor:
Muhammad Ameen Jamal, Yixiao Cheng, Deling Jiao, Wen Cheng, Di Zou, Xia Wang, Taiyun Wei, Jianxiong Guo, Kaixiang Xu, Heng Zhao, Shaoxia Pu, Chang Yang, Yubo Qing, Baoyu Jia, Honghui Li, Rusong Zhao, Hong-Ye Zhao, Hong-Jiang Wei
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-18 (2024)
Abstract Background Infertility is a growing global health concern affecting millions of couples worldwide. Among several factors, an extreme body weight adversely affects reproductive functions. Leptin is a well-known adipokine that serves as an end
Externí odkaz:
https://doaj.org/article/568d092957b34cca8761e6cc29427490
Publikováno v:
Journal of Basic and Applied Zoology, Vol 85, Iss 1, Pp 1-14 (2024)
Abstract Background PCOS is a serious endocrine-metabolic condition characterized by hyperandrogenemia, anovulation, or oligo-ovulation, and links to obesity, insulin resistance, and an elevated risk of type 2 diabetes mellitus. The pathophysiology o
Externí odkaz:
https://doaj.org/article/f13e89c1bd644afda294ec35be5e02b9
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-6 (2024)
Abstract Background 17-Hydroxylase deficiency is the rarest form of congenital adrenal hyperplasia, a disorder that affects steroidogenesis, causing abnormal hormone levels. Studies have shown a clear association between 17-hydroxylase deficiency and
Externí odkaz:
https://doaj.org/article/746ee57f4c7f4370a2c39fa000c86d2d
Autor:
Alina Bilyalova, Airat Bilyalov, Nikita Filatov, Elena Shagimardanova, Andrey Kiyasov, Maria Vorontsova, Oleg Gusev
Publikováno v:
Laboratory Animal Research, Vol 40, Iss 1, Pp 1-11 (2024)
Abstract The study of adrenal disorders is a key component of scientific research, driven by the complex innervation, unique structure, and essential functions of the adrenal glands. This review explores the use of non-traditional animal models for s
Externí odkaz:
https://doaj.org/article/95da2d6437c7406c8fe39bbc6e080996
Autor:
Loise Serra, Anthony Estienne, Alice Bongrani, Christelle Ramé, Giovanni Caria, Claire Froger, Claudy Jolivet, Abel Henriot, Laurence Amalric, Emilie Corbin, Fabrice Guérif, Pascal Froment, Joëlle Dupont
Publikováno v:
Toxicology Reports, Vol 12, Iss , Pp 65-81 (2024)
Polycystic ovarian syndrome (PCOS), frequently associated to obesity, is the main reproductive disorder in women in age to procreate. Some evidence suggests that pesticides can result in alterations of the female reproductive system, including polycy
Externí odkaz:
https://doaj.org/article/b5fb94ad2f504dbaa7075e62ab010939
Autor:
Paraskevi Vazakidou, Sara Evangelista, Tianyi Li, Laetitia L. Lecante, Kristine Rosenberg, Jacco Koekkoek, Andres Salumets, Agne Velthut-Meikas, Pauliina Damdimopoulou, Séverine Mazaud-Guittot, Paul A. Fowler, Pim E.G. Leonards, Majorie B.M. van Duursen
Publikováno v:
Reproductive Biology and Endocrinology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Reproduction in women is at risk due to exposure to chemicals that can disrupt the endocrine system during different windows of sensitivity throughout life. Steroid hormone levels are fundamental for the normal development and fun
Externí odkaz:
https://doaj.org/article/e590b20a8cd549beab606e9ee9d68ed6
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e36466- (2024)
Vitamin D deficiency poses a widespread health challenge, shaped by environmental and genetic determinants. A recent discovery identified a genetic regulator, rs11542462, in the SDR42E1 gene, though its biological implications remain largely unexplor
Externí odkaz:
https://doaj.org/article/987e5fa029a7439c987df77458479158
Autor:
Marie-Christin Jäger, Víctor González-Ruiz, Friedrich L. Joos, Denise V. Winter, Julien Boccard, Thorsten Degenhardt, Steve Brand, Serge Rudaz, George R. Thompson, Alex Odermatt
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The triazole antifungals posaconazole and itraconazole can cause pseudohyperaldosteronism with hypertension and hypokalemia, edema, and gynecomastia by inhibiting steroid synthesis and metabolism. Mechanisms underlying pseudohyperaldosteronism includ
Externí odkaz:
https://doaj.org/article/afe101840dac4196825e2d8599c4e6ac
Autor:
Jianmin Sang, Zhongyao Ji, Huitao Li, Hong Wang, Hehua Quan, Yang Yu, Jingyun Yan, Zhixiang Mao, Yiyan Wang, Linxi Li, Ren-shan Ge, Han Lin
Publikováno v:
Environment International, Vol 190, Iss , Pp 108827- (2024)
Triclosan is a potent antibacterial compound widely used in everyday products. Whether triclosan affects Leydig cell function in adult male rats remains unknown. In this study, 0, 50, 100, or 200 mg/kg/day triclosan was gavaged to Sprague-Dawley male
Externí odkaz:
https://doaj.org/article/8c1c830780af4e758607ab19cd186dc6
Autor:
Ali Afzal, Yue Zhang, Hanan Afzal, Umair Ali Khan Saddozai, Lei Zhang, Xin-Ying Ji, Muhammad Babar Khawar
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Autophagy is an evolutionarily conserved cellular recycling process that maintains cellular homeostasis. Despite extensive research in endocrine contexts, the role of autophagy in ovarian and testicular steroidogenesis remains elusive. The significan
Externí odkaz:
https://doaj.org/article/de7d371306c645d98093b2f5aa2e1e89