Zobrazeno 1 - 10
of 249
pro vyhledávání: '"Steroid-induced osteonecrosis of the femoral head"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract This study aimed to investigate the regulatory mechanisms that influenced autophagy in Steroid-induced necrosis of the femoral head (SONFH) by constructing a competing endogenous RNA (ceRNA) network. Blood sample data from the SONFH patients
Externí odkaz:
https://doaj.org/article/6faf94e023ad4130aca9c6cf436ea55c
Autor:
Daqi Jia, Yue Zhang, Huaqiang Li, Chunfang Guo, Yipeng Wu, Xiangwen Shi, Li Yang, Jieyu Mo, Xia Liu, Yongqing Xu
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-12 (2024)
Abstract Background Femoral head necrosis is a common orthopedic disease that results in significant physical disability in patients. Early prediction and diagnosis of steroid-induced osteonecrosis of the femoral head (SONFH) are crucial for the prev
Externí odkaz:
https://doaj.org/article/ad83215b505b409ba0b93bd5f5aeedf0
Publikováno v:
EFORT Open Reviews, Vol 9, Iss 11, Pp 1013-1022 (2024)
The pathogenesis of steroid-induced osteonecrosis of the femoral head (SONFH) remains unclear; however, emerging evidence suggests that mitochondrial injury plays a significant role. This review aims to elucidate the involvement of mitochondrial dysf
Externí odkaz:
https://doaj.org/article/5dcd40ef3d4d42d9ab4ee43fadca744f
Autor:
Longyu Li, Shangkun Zhao, Zikuan Leng, Songfeng Chen, Yifang Shi, Lijun Shi, Jinfeng Li, Keya Mao, Hai Tang, Bin Meng, Yisheng Wang, Guowei Shang, Hongjian Liu
Publikováno v:
Annals of Medicine, Vol 56, Iss 1 (2024)
Background Osteonecrosis of the femoral head (ONFH) is a refractory orthopedic disease with a high disability rate. Long-term administration of steroids is the most common pathogenic factor for non-traumatic ONFH. Early diagnosis of steroid-induced o
Externí odkaz:
https://doaj.org/article/19c0afc5d9904d60868838659f03c49e
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-15 (2024)
Abstract Inflammatory reactions are involved in the development of steroid-induced osteonecrosis of the femoral head(ONFH). Studies have explored the therapeutic efficacy of inhibiting inflammatory reactions in steroid-induced ONFH and revealed that
Externí odkaz:
https://doaj.org/article/0175f6db8f324896a81216d0886c130d
Publikováno v:
Zhongguo quanke yixue, Vol 26, Iss 29, Pp 3674-3682 (2023)
Background Steroid-induced osteonecrosis of the femoral head (SONFH) is common and disabling. The efficacy of Huoxue Tongluo Capsule has been consistently demonstrated in the prevention and treatment of osteonecrosis of the femoral head, but there is
Externí odkaz:
https://doaj.org/article/824fdff1a24140238bc0628dc28ff19c
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Oxidative stress was closely related to the occurrence and development of Steroid-induced osteonecrosis of the femoral head (SIONFH). 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a important index of oxidative stress. The aim of this s
Externí odkaz:
https://doaj.org/article/29783647568f4d12a0a9391b6a2265e1
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Osteonecrosis of the femoral head (ONFH) is becoming a prevalent global health problem. 4-Hydroxynonenal (4-HNE) serves as a common marker of oxidative stress. This study aims to study the potential role of 4-HNE in the progressio
Externí odkaz:
https://doaj.org/article/52dd2841a81c486cbeb71c026b9a9a67
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Purpose Steroid-induced necrosis of the femoral head (SONFH) is a refractory orthopedic hip disease occurring in young and middle-aged people, with glucocorticoids being the most common cause. Previous experimental studies have shown that ce
Externí odkaz:
https://doaj.org/article/83f57a91ba95468590bc637b1193c6ec
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-12 (2023)
Abstract Background Steroid-induced osteonecrosis of the femoral head (SONFH) is the necrosis of the femur bone caused by prolonged and massive use of corticosteroids. The present study probed into the significance of Astragalus polysaccharide (APS)
Externí odkaz:
https://doaj.org/article/d79d65a7879a48c9a66a967e0a2d555f