Zobrazeno 1 - 10
of 1 201
pro vyhledávání: '"Steroid refractory"'
Autor:
Zicheng Gao, Zhiping Fan, Zhi Liu, Xu Ye, Yunxin Zeng, Li Xuan, Fen Huang, Ren Lin, Jing Sun, Qifa Liu, Na Xu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundSteroid-resistant (SR) lower gastrointestinal (LGI) tract graft-versus-host disease (GVHD) is the predominant cause of morbidity and mortality from GVHD after allogeneic hematopoietic stem cell transplantation (allo-HSCT). The role of vedol
Externí odkaz:
https://doaj.org/article/5e38a3e192fb498caca6938fc045f775
Autor:
Haixia Fu, Xueyan Sun, Ren Lin, Yu Wang, Li Xuan, Han Yao, Yuanyuan Zhang, Xiaodong Mo, Meng lv, Fengmei Zheng, Jun Kong, Fengrong Wang, Chenhua Yan, Tingting Han, Huan Chen, Yao Chen, Feifei Tang, Yuqian Sun, Yuhong Chen, Lanping Xu, Kaiyan Liu, Xi Zhang, Qifa Liu, Xiaojun Huang, Xiaohui Zhang
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background For patients with steroid-refractory acute graft-versus-host disease (SR-aGVHD), effective second-line regimens are urgently needed. Mesenchymal stromal cells (MSCs) have been used as salvage regimens for SR-aGVHD in the past. How
Externí odkaz:
https://doaj.org/article/c450aca802824f03b9e1a77e5f228c85
Autor:
Cong Cheng, Dao-Xing Deng, Xiao-Hui Zhang, Lan-Ping Xu, Yu Wang, Chen-Hua Yan, Huan Chen, Yu-Hong Chen, Wei Han, Feng-Rong Wang, Jing-Zhi Wang, Yu-Qian Sun, Xiao-Jun Huang, Xiao-Dong Mo
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Intestinal steroid refractory acute graft-versus-host disease (SR-aGVHD) is the major cause of mortality in allogeneic hematopoietic stem cell transplantation (allo-HSCT). This retrospective cohort study aimed to identify the relationship between dif
Externí odkaz:
https://doaj.org/article/b19da2776ae4414c8af664ab9f440daa
Autor:
Halvard Bonig, Mareike Verbeek, Peter Herhaus, Krischan Braitsch, Gernot Beutel, Christoph Schmid, Nadine Müller, Gesine Bug, Michaela Döring, Arend von Stackelberg, Johanna Tischer, Francis Ayuk, Gerald Wulf, Udo Holtick, Lisa-Marie Pfeffermann, Bernd Jahrsdörfer, Hubert Schrezenmeier, Selim Kuci, Zyrafete Kuci, Anke Zens, Michael Tribanek, Robert Zeiser, Sabine Huenecke, Peter Bader
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Patients with steroid-refractory acute graft-versus-host disease (aGvHD) not tolerating/responding to ruxolitinib (RR-aGvHD) have a dismal prognosis. Methods We retrospectively assessed real-world outcomes of RR-aGvHD treated with
Externí odkaz:
https://doaj.org/article/1942e01c115d422bbf46c4611ede54dd
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 15, p 4509 (2024)
Acute Severe Ulcerative Colitis (ASUC) is a severe form of ulcerative colitis relapse which requires hospitalization and intensive medical intervention to avoid colectomy. The timely recognition of patients at risk of corticosteroid failure and the e
Externí odkaz:
https://doaj.org/article/76050d00a41c480cb47dfa335faa48f7
Autor:
Yijun Cai, Amir Ali, Elan Filler, Rua Bayati, Tanjia Toma, Omar Zaki, George Yaghmour, Abdullah Ladha, Karrune Woan, Eric Tam, Preet M. Chaudhary
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Graft-versus-host disease (GVHD) is a common complication in patients receiving allogeneic hematopoietic stem cell transplantation (HSCT). GVHD is characterized as either acute or chronic based on symptomatology and histopathological findings. Despit
Externí odkaz:
https://doaj.org/article/b13c05542f3543b3a18cab7a43e213c0
Autor:
Olaf Penack, Christophe Peczynski, William Boreland, Jessica Lemaitre, Ksenia Afanasyeva, Brian Kornblit, Manuel Jurado, Carmen Martinez, Annalisa Natale, Jose Antonio Pérez-Simón, Lucia Brunello, Daniele Avenoso, Stefan Klein, Zubeyde Nur Ozkurt, Concha Herrera, Stina Wichert, Patrizia Chiusolo, Eleni Gavriilaki, Grzegorz W. Basak, Hélène Schoemans, Christian Koenecke, Ivan Moiseev, Zinaida Peric
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionExtracorporal Photophoresis (ECP) is in clinical use for steroid-refractory and steroid-dependent acute GVHD (SR-aGVHD). Based on recent Phase-III study results, ruxolitinib has become the new standard of care for SR-aGVHD. Our aim was to
Externí odkaz:
https://doaj.org/article/c87c15a038f44831ac8aefe6cd59a145
Autor:
Francesca Gottardi, Davide Leardini, Edoardo Muratore, Francesco Baccelli, Sara Cerasi, Francesco Venturelli, Andrea Zanaroli, Tamara Belotti, Arcangelo Prete, Riccardo Masetti
Publikováno v:
Frontiers in Transplantation, Vol 2 (2023)
Systemic steroids are still the first-line approach in acute graft-versus-host disease (aGvHD), and the backbone of chronic GvHD management. Refractoriness to steroid represent a major cause of morbidity and non-relapse mortality after hematopoietic
Externí odkaz:
https://doaj.org/article/adc6fd013b8647ef80a014582d89437d
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
The use of immune checkpoint inhibitors (ICIs) for treating several types of cancer is increasing, but they may be associated with immune-related adverse events (irAEs). Pancreatitis is a rare irAE, mostly responsive to steroid treatment. There are n
Externí odkaz:
https://doaj.org/article/2d15be14dfa74d859193b42bd4ab04a2
Autor:
Aylin Lindemann, Dominik Roth, Kristina Koop, Clemens Neufert, Sebastian Zundler, Raja Atreya, Markus F. Neurath, Moritz Leppkes
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Background and aimsAcute severe steroid-refractory ulcerative colitis remains a medically challenging condition with frequent need of surgery. It can be treated with the calcineurin inhibitor cyclosporine A with the need for therapeutic drug monitori
Externí odkaz:
https://doaj.org/article/1cd45e5b0692471ea658653720605cdf