Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Steroid Hormones and Receptors"'
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/ddec95047f1f4551aa3026a2ff16a47e
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/eeaa7dd8c8484341aafd89c216c14b74
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Steroid hormones govern the complex, cyclic changes of the endometrium, predominantly through their receptors. An interplay between steroid hormones and epigenetic mechanisms controls the dynamic endometrial gene regulation. Abnormalities in expressi
Externí odkaz:
https://doaj.org/article/79e09a113dbe47f2a03c4b3f6f113052
Autor:
Paola Aguiari, Anna Milanesi, Astgik Petrosyan, Yan-Yun Liu, Laura Perin, Sheue-Yann Cheng, Gregory A. Brent
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Journal of the Endocrine Society
Scientific Reports
Journal of the Endocrine Society
Myopathic changes, including muscular dystrophy and weakness, are commonly described in hypothyroid and hyperthyroid patients. Thyroid hormone signaling, via activation of thyroid nuclear receptor alpha (THRA), plays an essential role in maintaining
Publikováno v:
Journal of the Endocrine Society
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
The glucocorticoid receptor (GR) is a ligand-regulated transcription factor (TF) that controls the tissue- and gene-specific transactivation and transrepression of thousands of target genes. Distinct GR DNA binding sequences with activating or repres
Publikováno v:
Journal of the Endocrine Society
Steroid fatty acyl esters (FAEs) are a class of steroid conjugates that are abundant in circulation, have long half-lives, and are stored in lipid-rich tissues. Steroid-FAEs are present in many species, but their functions are poorly understood. They
Autor:
Fred C. G. J. Sweep, Paul N. Span, Adina F. Turcu, Mariska A M Schröder, Hedi L Claahsen-van der Grinten, Antonius E. van Herwaarden, Richard J. Auchus, Patrick O’Day
Publikováno v:
Journal of the Endocrine Society
Context Testicular adrenal rest tumors (TART) are a common complication in males with classic 21-hydroxylase deficiency (21OHD). TART are likely to contribute to the androgen excess in 21OHD patients, but a direct quantification of steroidogenesis fr
Publikováno v:
Journal of the Endocrine Society
Bile acids (BAs) have gained traction not just as emulsifiers of fat, but also as hormones. Nuclear receptor Farnesoid X receptor (FXR) is the master regulator of BAs and can also control glucose and lipid metabolism. We examined if FXR contributed t
Autor:
Olga Astapova, Stephen R. Hammes
Publikováno v:
Journal of the Endocrine Society
Androgens are important in female reproduction, as evident from studies of mouse ovary-specific androgen receptor knockout models characterized by sub-fertility and diminished ovarian reserve. Androgen activity specifically promotes granulosa cell pr
Publikováno v:
Journal of the Endocrine Society
Estrogen receptor alpha (ERα), a transcription factor implicated in induction of cell growth in breast cancer, is a therapeutic target that is expressed in >70% of breast tumors. The transcriptional activity of ERα is controlled by ligands and incr